- Conditions
- Emphysema
- Interventions
- Sildenafil 20 MG, Placebo Oral Tablet, Pulse wave velocity, Carotid artery compliance and stiffness, Pressure wave reflection
- Drug · Diagnostic Test
- Lead sponsor
- Eric A. Hoffman
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 162 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
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Showing 25–48
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Pulmonary Disease, Chronic Obstructive
- Interventions
- Tetrahydrobiopterin (BH4), Antioxidant Cocktail
- Drug · Dietary Supplement
- Lead sponsor
- Augusta University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2015
- U.S. locations
- 1
- States / cities
- Augusta, Georgia
- Conditions
- Chronic Kidney Disease, Cardiovascular Disease
- Interventions
- Lanthanum carbonate, placebo, Ascorbic Acid, Nitroglycerin, Flow-mediated dilation measurement, Aortic pulse-wave velocity, Endothelial cell collection
- Drug · Procedure
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 40 Years to 79 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Hypertension, Cardiovascular Diseases, Vascular Diseases
- Interventions
- 25 g of Freeze-dried Strawberry Powder, 50 g of Freeze-dried Strawberry Powder, Placebo Powder
- Dietary Supplement
- Lead sponsor
- Florida State University
- Other
- Eligibility
- 45 Years to 65 Years · Female only
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Tallahassee, Florida
- Conditions
- Hypotension, Arterial Stiffness
- Interventions
- SphygmoCor system
- Device
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Vascular Dilation, Arterial Stiffness
- Interventions
- BEET IT - Concentrate Beet root juice, BEET IT - Concentrate Beet root juice (nitrate depleted)
- Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 45 Years to 75 Years · Female only
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Pulmonary Disease, Chronic Obstructive (COPD), Cognitive Impairment
- Interventions
- Neuropsychological Assessment, Spirometry, Arterial Blood Gas, Diffusion Capacity of the Lung for Carbon Monoxide, 6 Minute Walk Test, Systemic Vascular Measures, Blood Biomarkers, Symptom Questionnaire Measures, Brain MRI
- Behavioral · Procedure · Diagnostic Test + 1 more
- Lead sponsor
- Karin Hoth
- Other
- Eligibility
- 30 Years to 85 Years
- Enrollment
- 170 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2025
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Vasodilation, Arterial Stiffness
- Interventions
- Acetylcholine, Sodium Nitroprusside, Ascorbic Acid
- Drug
- Lead sponsor
- Colorado State University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Fort Collins, Colorado
- Conditions
- Hypertension
- Interventions
- Bosentan, Placebo
- Drug
- Lead sponsor
- Augusta University
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 320 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2026
- U.S. locations
- 1
- States / cities
- Augusta, Georgia
- Conditions
- Healthy
- Interventions
- Pulse wave velocity measurement Photoplethysmogram, tonometer
- Device
- Lead sponsor
- Nonin Medical, Inc
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Cardiovascular Diseases, Hypertension
- Interventions
- Normotensive, Hypertensives
- Other · Drug
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 50 Years to 70 Years · Female only
- Enrollment
- 8 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Deep Vein Thrombosis, Pulmonary Embolism
- Interventions
- The Focus™ Neuromuscular Stimulation System
- Device
- Lead sponsor
- University at Buffalo
- Other
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2007
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Blood Pressure
- Interventions
- Freeze-dried Blueberry Powder, Placebo
- Dietary Supplement
- Lead sponsor
- Florida State University
- Other
- Eligibility
- 45 Years to 65 Years · Female only
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Tallahassee, Florida
- Conditions
- Obesity, Pre-hypertension, Hypertension
- Interventions
- Resistance exercise training, Hypocaloric diet, Resistance exercise training & diet
- Other
- Lead sponsor
- Florida State University
- Other
- Eligibility
- 40 Years to 65 Years · Female only
- Enrollment
- 41 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Tallahassee, Florida
- Conditions
- Fibromuscular Dysplasia of Arteries, Segmental Arterial Mediolysis, Spontaneous Coronary Artery Dissection, Atherosclerosis of Artery
- Interventions
- Shear Wave Elastography, Pulse Wave Imaging, Contrast-Enhanced Ultrasound, Strain Imaging, 3-D Volume Ultrasound
- Device · Drug · Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Hypertension, Prehypertension
- Interventions
- Intervention
- Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 271 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Arterial Stiffness
- Interventions
- Sleep Loss
- Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 20 Years to 29 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Breast Neoplasms
- Interventions
- Ultrasound- Virtual Touch Tissue Imaging Quantification
- Device
- Lead sponsor
- Heidelberg University
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 1,304 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Youngstown, Ohio
- Conditions
- End Stage Renal Disease
- Interventions
- there is no intervention
- Other
- Lead sponsor
- Children's National Research Institute
- Other
- Eligibility
- 3 Years to 21 Years
- Enrollment
- 150 participants
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Pre-Eclampsia
- Interventions
- StO2 and EndoPAT
- Diagnostic Test
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Type 2 Diabetes
- Interventions
- vitamin D3, cholecalciferol, Inactive comparator
- Dietary Supplement
- Lead sponsor
- Augusta University
- Other
- Eligibility
- 19 Years to 60 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Augusta, Georgia
- Conditions
- Obesity, Pre-hypertension, Hypertension
- Interventions
- Whole Body Vibration Training, Hypocaloric diet, Whole body vibration training & diet
- Other
- Lead sponsor
- Florida State University
- Other
- Eligibility
- 45 Years to 65 Years · Female only
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Tallahassee, Florida
- Conditions
- Obesity, Pre-hypertension, Hypertension
- Interventions
- Stretching Training
- Other
- Lead sponsor
- Florida State University
- Other
- Eligibility
- 50 Years to 65 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011
- U.S. locations
- 1
- States / cities
- Tallahassee, Florida
- Conditions
- Atherosclerotic Cardiovascular Disease
- Interventions
- Coronary Artery Calcium Scan, Carotid Artery Ultrasound, Lipoprotein(a) Measurement, Vascular Function Testing
- Diagnostic Test
- Lead sponsor
- St. Jude Children's Research Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 650 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee