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Showing 1–24 of 249 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Pulse oximeter Clear all
Completed No phase listed Observational Accepts healthy volunteers

Pulse Oximetry Performance Comparison in Newborns

NCT06637917
View directory record Official record
Conditions
Newborn, Birth, Preterm
Interventions
OxySoftN™ Neonatal-Adult SpO2 Sensor with N600X Nellcor™ Patient Monitoring System, LNCS® NEO SpO2 Sensor with RAD-97™ Pulse CO-Oximeter, 1041PTS (or similar) Kendall™ Neonatal Electrodes with IntelliVue MP5 Portable Patient Monitor
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
29 Weeks and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Los Angeles, California • St Louis, Missouri • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 2, 2026, 4:42 PM EDT
Completed No phase listed Observational

Verification of Pulse Oximetry in Neonatal Population

NCT00751439
View directory record Official record
Conditions
Respiratory Distress Syndrome
Interventions
Not listed
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
1 Day to 30 Days
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 10, 2010 · Synced Sep 2, 2026, 4:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pulse Oximeter Validation Study for the Perin Health Patch

NCT07027150
View directory record Official record
Conditions
Hypoxia
Interventions
Chest Worn Pulse Oximeter
Device
Lead sponsor
Perin Health Devices
Industry
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vital USA Respiratory Rate Validation In Adults

NCT04292639
View directory record Official record
Conditions
Respiratory Complication
Interventions
The Vital Detect Pulse Oximeter
Device
Lead sponsor
Vital USA, Inc.
Industry
Eligibility
18 Years to 52 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

EmbracePlus SpO2 Accuracy Validation

NCT04964609
View directory record Official record
Conditions
Oximetry
Interventions
EmbracePlus
Device
Lead sponsor
Empatica, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2022 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Early Phase 1 Interventional

Effect of Changing Physiological Conditions on Myogenic Oscillations: Pilot Study

NCT03719001
View directory record Official record
Conditions
Vascular Diseases
Interventions
Phenylephrine, Dexmedetomidine, Clevidipine, tetanic stimulus, Increased venous pressure, Calcium Chloride
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Sep 2, 2026, 4:42 PM EDT
Terminated No phase listed Interventional Results available

Validation of RPVi as a Parameter to Predict Fluid Responsiveness

NCT03706430
View directory record Official record
Conditions
Surgery, Anesthesia
Interventions
Pulse CO-Oximeter sensor
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Accuracy of Methemoglobin Measurement for Rainbow Universal Pulse Oximeter Sensor

NCT03125005
View directory record Official record
Conditions
Healthy
Interventions
Rainbow Universal Pulse Oximeter Sensor
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
2
States / cities
Irvine, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 26, 2017 · Synced Sep 2, 2026, 4:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Accuracy of Pulse Oximeters With Profound Hypoxia During Motion

NCT04814342
View directory record Official record
Conditions
Hypoxia
Interventions
Pulse oximeter
Device
Lead sponsor
Nihon Kohden
Industry
Eligibility
18 Years to 50 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional Results available

Use of Remote Monitoring for COVID-19 Patient

NCT04425720
View directory record Official record
Conditions
COVID
Interventions
LifeSignals Biosensor 1AX*, Standard of Care
Device · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 23, 2022 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional

Home Pulse Oximeter Use in Patients With COVID-19

NCT04373161
View directory record Official record
Conditions
Sars-CoV2, COVID-19, COVID
Interventions
Home Pulse Oximetry Monitoring
Device
Lead sponsor
Swedish Hospital
Other
Eligibility
18 Years and older
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Sep 2, 2026, 4:42 PM EDT
Not listed Not applicable Interventional

Assessing the Performance of Wesper Lab for Sleep Apnea Diagnosis in Pediatric Populations

NCT06218186
View directory record Official record
Conditions
Sleep Apnea, Sleep Apnea Syndromes in Children, Sleep Apnea Syndromes
Interventions
Medical Device: Wesper Lab Home Sleep Test
Device
Lead sponsor
Wesper Inc
Industry
Eligibility
2 Years to 21 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Edmond, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Sep 2, 2026, 4:42 PM EDT
Completed No phase listed Observational

Accuracy of Peripheral Pulse Oximetry Versus Arterial Co-oximeter in Children With Cyanotic Heart Disease

NCT02237014
View directory record Official record
Conditions
Cyanotic Heart Disease
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
Up to 10 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2017 · Synced Sep 2, 2026, 4:42 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neonatal Pulse Oximetry Disparities Due to Skin Pigmentation

NCT06063148
View directory record Official record
Conditions
Skin Pigment, Pulse Oximetry
Interventions
Enrolled Participant
Device
Lead sponsor
University of California, Davis
Other
Eligibility
Up to 10 Days
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Sacramento, California • Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 2, 2026, 4:42 PM EDT
Completed No phase listed Observational Results available

Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO18)

NCT05807464
View directory record Official record
Conditions
Hypoxia
Interventions
Pulse Oximeter
Device
Lead sponsor
Nihon Kohden
Industry
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Accuracy of Noninvasive Hemoglobin Measurement (SpHb) Using Rainbow DCI Pulse Oximeter Sensor

NCT03124693
View directory record Official record
Conditions
Healthy, Surgery
Interventions
Rainbow DCI pulse oximeter sensor
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
3
States / cities
Irvine, California • Loma Linda, California • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2017 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

INVSENSOR00013 Respiratory Rate Clinical Performance Study

NCT03440619
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00013
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Digital Ankle Brachial Index (ABI) as a Screening Tool in Detecting Peripheral Arterial Disease

NCT03161327
View directory record Official record
Conditions
Peripheral Artery Disease, Amputation, Smoking, Diabetes, Hypercholesterolemia, Hypertension
Interventions
ABI using QuantaFlo™
Device
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 90 Years
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Sep 2, 2026, 4:42 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Rad-67 Repeatability and Reproducibility

NCT04196907
View directory record Official record
Conditions
Healthy
Interventions
Rad-67 Pulse CO-Oximeter and DCI Mini sensor
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Sep 2, 2026, 4:42 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00006

NCT03435211
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00006
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Tissue Oxygenation Measurement Using Multimodal Devices

NCT05784103
View directory record Official record
Conditions
Oxygen Saturation
Interventions
Clarifi Modulum, Perimed PeriFlux 5000, Apple Watch Oxygen Sensor, Innovo iP 900AP
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Indianapolis, Indiana • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 2, 2026, 4:42 PM EDT
Completed No phase listed Observational

Pulse Oximetry Errors in Hospitalized Patients Across Varying Skin Pigmentation

NCT05554510
View directory record Official record
Conditions
Hypoxemia, Pulse Oximetry, Skin Pigment
Interventions
Observational
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
757 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2025 · Synced Sep 2, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Desaturation Validation of INVSENSOR00031

NCT03783780
View directory record Official record
Conditions
Healthy
Interventions
INVSENSOR00031
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 2, 2026, 4:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Dysfunctional Hemoglobin

NCT02262195
View directory record Official record
Conditions
Elevated Levels of Carboxyhemoglobin and Methemoglobin
Interventions
Elevated levels of carboxyhemoglobin
Other
Lead sponsor
Nonin Medical, Inc
Industry
Eligibility
18 Years to 45 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2015 · Synced Sep 2, 2026, 4:42 PM EDT