Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 5, 2026, 9:29 AM EDT

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Showing 1–24 of 55 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Cardiovascular Risk Factor
Interventions
PhysioWave Cardiovascular Analyzer, AtCor XCEL PWA & PWV, Detecto SOLO
Device
Lead sponsor
PhysioWave, Inc.
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Walnut Creek, California
Completed No phase listed Observational Accepts healthy volunteers

High Resolution Phenotyping in Healthy Humans

NCT00943774
Conditions
Pressor Response, Baroreflex Sensitivity, Blood Pressure Variability, Heart Rate Variability, Arterial Catecholamines
Interventions
Physiological maneuvers
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Hypertension, Cardiovascular Diseases, Vascular Diseases
Interventions
25 g of Freeze-dried Strawberry Powder, 50 g of Freeze-dried Strawberry Powder, Placebo Powder
Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tallahassee, Florida
Conditions
Low Back Pain
Interventions
Spinal Manipulation, Light Massage, Pulsed Ultrasound
Procedure
Lead sponsor
University of Western States
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Black Women's Life Experience On Cardiovascular Health Via Ongoing Monitoring

NCT06150989
Conditions
Cardiovascular Diseases, Heart Disease Risk Factors
Interventions
Observational Group
Behavioral
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Arlington, Texas
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Sodium Nitrite to Treat Arterial Aging

NCT02022670
Conditions
Vascular Aging
Interventions
Placebo, Sodium Nitrite
Drug
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years to 79 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boulder, Colorado
Recruiting Not applicable Interventional Accepts healthy volunteers

The Validation Study of Bioelectronics

NCT05397951
Conditions
Healthy, Health Behavior
Interventions
Multi-modality Noninvasive Biosensor, Oximeter, Portable Blood Pressure Monitor, Vicorder Pulse Wave Velocity Monitor
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed No phase listed Observational Accepts healthy volunteers

COPD-Related Physiology and the Brain

NCT03269721
Conditions
Pulmonary Disease, Chronic Obstructive (COPD), Cognitive Impairment
Interventions
Neuropsychological Assessment, Spirometry, Arterial Blood Gas, Diffusion Capacity of the Lung for Carbon Monoxide, 6 Minute Walk Test, Systemic Vascular Measures, Blood Biomarkers, Symptom Questionnaire Measures, Brain MRI
Behavioral · Procedure · Diagnostic Test + 1 more
Lead sponsor
Karin Hoth
Other
Eligibility
30 Years to 85 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Blood Pressure
Interventions
Freeze-dried Blueberry Powder, Placebo
Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Tallahassee, Florida
Terminated Not applicable Interventional Accepts healthy volunteers

Acute Sleep Loss and Arterial Stiffness

NCT05940467
Conditions
Arterial Stiffness
Interventions
Sleep Loss
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
20 Years to 29 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Secondary Hyperparathyroidism, Chronic Kidney Disease
Interventions
Paricalcitol, Ergocalciferol
Drug
Lead sponsor
Salem Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Salem, Virginia
Completed Not applicable Interventional Accepts healthy volunteers

Effects of High Functional Resistance Training Program on Arterial Stiffness

NCT06935318
Conditions
Training Study
Interventions
Exercise, Control
Other
Lead sponsor
Salisbury University
Other
Eligibility
18 Years to 40 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Salisbury, Maryland
Conditions
Hypotension, Arterial Stiffness
Interventions
SphygmoCor system
Device
Lead sponsor
University of Iowa
Other
Eligibility
50 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Black Forest Cocoa Flavanol Supplementation and Health Trial

NCT07747714
Conditions
Endothelial Function, Oxidative Stress, Inflamation, Vascular Health
Interventions
Cocoa Flavanol Supplement, Low-Flavanol Control Powder
Dietary Supplement
Lead sponsor
The Black Forest LLC
Industry
Eligibility
30 Years to 75 Years · Male only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Miami, Florida
Conditions
Hypertension
Interventions
LCZ696, Olmesartan, LCZ696 matching placebo, Olmesartan matching placebo, amlodipine, hydrochlorothiazide
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
60 Years and older
Enrollment
454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
11
States / cities
Clearwater, Florida • Chicago, Illinois • Baltimore, Maryland + 8 more
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Targeting ER Stress in Vascular Dysfunction

NCT04001647
Conditions
Vasodilation, Arterial Stiffness
Interventions
Acetylcholine, Sodium Nitroprusside, Ascorbic Acid
Drug
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Fort Collins, Colorado
Recruiting Not applicable Interventional Accepts healthy volunteers

Sitting Interruption and Whole-body Cardiovascular Health

NCT05316571
Conditions
Sedentary Behavior, Sedentary Time
Interventions
One 5-Minute Walking Bout Each Hour, One 15-Minute Standing Bout Each Hour, One 5-Minute Walking Bout and One 15-Minute Standing Bout Each Hour, Uninterrupted Sitting
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
30 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Atherosclerotic Cardiovascular Disease
Interventions
Coronary Artery Calcium Scan, Carotid Artery Ultrasound, Lipoprotein(a) Measurement, Vascular Function Testing
Diagnostic Test
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Memphis, Tennessee
Completed Phase 4 Interventional Results available

Phosphate Lowering in CKD Trial

NCT02209636
Conditions
Chronic Kidney Disease, Cardiovascular Disease
Interventions
Lanthanum carbonate, placebo, Ascorbic Acid, Nitroglycerin, Flow-mediated dilation measurement, Aortic pulse-wave velocity, Endothelial cell collection
Drug · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 79 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Post-Op Complication, Arterial Stiffness
Interventions
Not listed
Lead sponsor
Kenichi Ueda
Other
Eligibility
40 Years to 100 Years
Enrollment
543 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Not applicable Interventional Results available

Effect of Reducing Sedentary Behavior on Blood Pressure

NCT03307343
Conditions
Hypertension, Prehypertension
Interventions
Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 65 Years
Enrollment
271 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Endothelin Receptor Function and Acute Stress

NCT02116335
Conditions
Hypertension
Interventions
Bosentan, Placebo
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 50 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Breast Neoplasms
Interventions
Ultrasound- Virtual Touch Tissue Imaging Quantification
Device
Lead sponsor
Heidelberg University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Youngstown, Ohio
Conditions
Focus is on Healthy Subjects
Interventions
measure ascending aortic blood flow with pulse wave Doppler
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Charlottesville, Virginia