Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 7, 2026, 11:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–43 of 19 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Pupillometry Clear all
Recruiting No phase listed Observational

Characterization of Acute Pain

NCT07336264
View directory record Official record
Conditions
Acute Pain, Postoperative, Postoperative Pain, Acute Pain
Interventions
AlgometRx Nociometer
Device
Lead sponsor
Children's National Research Institute
Other
Eligibility
6 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 7, 2026, 11:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Intramuscular (IM) Oxytocin on Pupil Diameter and Heart Rate Variability (HRV)

NCT04105998
View directory record Official record
Conditions
Chronic Pain Due to Injury
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 66 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 9, 2022 · Synced Sep 7, 2026, 11:41 PM EDT
Recruiting No phase listed Observational

Measuring Analgesic Interventions

NCT03794362
View directory record Official record
Conditions
Pain
Interventions
Not listed
Lead sponsor
Julia Finkel
Other
Eligibility
7 Years to 21 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 7, 2026, 11:41 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age

NCT05391555
View directory record Official record
Conditions
Opioid Toxicity, Pupillary Miosis, Respiratory Depression
Interventions
Remifentanil Hydrochloride, Pupillometry measurement
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2025 · Synced Sep 7, 2026, 11:41 PM EDT
Not listed No phase listed Observational

Chromatic Pupillometry to Assess the Melanopsin-Light Pathway in Progressive Supranuclear Palsy

NCT03330353
View directory record Official record
Conditions
PSP - Progressive Supranuclear Palsy, PD - Parkinson's Disease, AD - Alzheimer's Disease, ALS (Amyotrophic Lateral Sclerosis)
Interventions
Pupillometry
Diagnostic Test
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
55 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Sep 7, 2026, 11:41 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects

NCT02083315
View directory record Official record
Conditions
Pain, Acute
Interventions
TRV130 1.5 mg, TRV130 3 mg, TRV130 4.5 mg, Morphine 10 mg, Placebo
Drug
Lead sponsor
Trevena Inc.
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Sep 7, 2026, 11:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

QST-Pupillometry in Sickle Cell Disease Patients

NCT02242058
View directory record Official record
Conditions
SCD With Severe Phenotype (HbSS, HbSβ0 Thalassemia, HbSOARab)
Interventions
Quantitative sensory testing
Other
Lead sponsor
Julia Finkel
Other
Eligibility
13 Years to 30 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2020 · Synced Sep 7, 2026, 11:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Ambient Light on the Parameters of the Pupillary Light Reflex

NCT01207817
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Pupillometry
Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 22, 2010 · Synced Sep 7, 2026, 11:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Investigation of Pupillometry as Guide for Extubation Readiness in Anesthetized Children

NCT04947397
View directory record Official record
Conditions
Anesthesia, Laryngospasm on Emergence
Interventions
Pupillometry
Diagnostic Test
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Years to 10 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 7, 2026, 11:41 PM EDT
Completed Not applicable Interventional

Optimal Time for In-situ Dry Needling to Affect the Autonomic Nervous System

NCT03728751
View directory record Official record
Conditions
Healthy
Interventions
Dry needling
Procedure
Lead sponsor
Florida Gulf Coast University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Hobart, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 1, 2018 · Synced Sep 7, 2026, 11:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Safety Study Looking at the Effects of Stendra on Vision

NCT02033200
View directory record Official record
Conditions
Vision
Interventions
Stendra 200 mg, Placebo
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
18 Years to 45 Years · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 12, 2015 · Synced Sep 7, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Spatial Cues, Task Demands, and Auditory Selective Attention

NCT07765186
View directory record Official record
Conditions
Bilateral Cochlear Implants, Hearing Loss, Bilateral, Healthy
Interventions
Existing bilateral cochlear implants, Normal Hearing Control
Device · Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 7, 2026, 11:41 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Relationships Among Pupil Responses to Light, Circadian Rhythms, and Sleep

NCT07753889
View directory record Official record
Conditions
Circadian Rhythm, Pupillometry, Sleep
Interventions
Ocular light exposure from portable light box
Other
Lead sponsor
Elizabeth B Klerman MD PhD
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2035
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 7, 2026, 11:41 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Utility of Pupillary Metrics in Diagnosis and Management of Concussion in Children

NCT04540445
View directory record Official record
Conditions
Brain Concussion, Reflex, Pupillary, Post-Concussion Syndrome, Brain Injuries, Traumatic
Interventions
Pupillary Assessment
Other
Lead sponsor
Children's Hospital of Orange County
Other
Eligibility
5 Years to 17 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Sep 7, 2026, 11:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessing Variability of the Ventilatory Response to Duffin's Rebreathing Procedure

NCT05168501
View directory record Official record
Conditions
Ventilation, Reproducibility, Physiology
Interventions
Rebreathing procedure
Other
Lead sponsor
Food and Drug Administration (FDA)
Federal
Eligibility
18 Years to 50 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 14, 2024 · Synced Sep 7, 2026, 11:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cortical Contributions to Frequency Following Responses and Modulation

NCT05010473
View directory record Official record
Conditions
Language
Interventions
Speech and non-speech sound stimulation
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
13 Years to 25 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 7, 2026, 11:41 PM EDT
Completed Phase 4 Interventional Results available

Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia

NCT01325493
View directory record Official record
Conditions
Idiopathic Scoliosis, Spondylolisthesis
Interventions
Ketamine, Normal Saline
Drug
Lead sponsor
Julia Finkel
Other
Eligibility
10 Years to 18 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Sep 7, 2026, 11:41 PM EDT
Enrolling by invitation Not applicable Interventional

Cortical Contributions to FFR: Post-Op Outcomes

NCT05214092
View directory record Official record
Conditions
Language
Interventions
Speech sound stimulation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 25 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 7, 2026, 11:41 PM EDT
Terminated Not applicable Interventional Results available

Infrared Pupillometry During General Anesthesia to Predict Pain

NCT02058511
View directory record Official record
Conditions
Postoperative Pain, Objective Assessment of Sedation
Interventions
Anesthesia Premedication, Induction and Maintenance, Pupillometry after administration of anesthetic drugs
Drug · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 7, 2026, 11:41 PM EDT