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ClinicalTrials.gov public records Last synced Sep 6, 2026, 5:32 AM EDT

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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Pyloromyotomy Clear all
Active, not recruiting Not applicable Interventional

Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes

NCT04696159
View directory record Official record
Conditions
Diabetes Mellitus, Gastroparesis With Diabetes Mellitus, Gastroparesis
Interventions
Pyloromyotomy
Procedure
Lead sponsor
Matthew Allemang
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Assess Optimal Postoperative Feeding Regiments Following Pyloromyotomy

NCT02415049
View directory record Official record
Conditions
Postoperative Feeding Following Pyloromyotomy
Interventions
Incremental Feeds, Ad lib feeds
Other
Lead sponsor
Indiana University
Other
Eligibility
2 Weeks to 10 Weeks
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 12, 2016 · Synced Sep 6, 2026, 5:32 AM EDT
Active, not recruiting Not applicable Interventional

Combined Role of Gastric Peroral Endoscopic Myotomy and Gastric Electrical Stimulator

NCT07526935
View directory record Official record
Conditions
Gastroparesis
Interventions
GES + Upper endoscopy, GES on + Upper endscopy, GES off + G-POEM, GES on + G-POEM
Device · Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 6, 2026, 5:32 AM EDT
Withdrawn Not applicable Interventional

Management of Symptomatic Gastric Sleeve Stenosis After Laparoscopic Sleeve Gastrectomy

NCT04781946
View directory record Official record
Conditions
Gastric Stenosis
Interventions
Endoscopic pneumatic balloon dilation, Gastric peroral endoscopic myotomy (G-POEM), Roux-en-Y gastric bypass (RYGB)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Phase 3 Interventional

Laparoscopic Versus Open Pyloromyotomy for Infants With Idiopathic Hypertrophic Pyloric Stenosis

NCT00195949
View directory record Official record
Conditions
Hypertrophic Pyloric Stenosis
Interventions
Laparoscopic pyloromyotomy
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
Up to 12 Weeks
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 5, 2007 · Synced Sep 6, 2026, 5:32 AM EDT
Recruiting Phase 2Phase 3 Interventional

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

NCT06721520
View directory record Official record
Conditions
Esophageal Cancer Surgery, Esophagectomy, Delayed Gastric Emptying Following Procedure, Esophageal Diseases, Esophageal Achalasia, Pylorus Dysfunction, Esophageal Dysmotility
Interventions
Botulinum Toxin A (Botox ), Pyloromyotomy
Biological · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Peroral Endoscopic Myotomy (POEM) for Esophageal Motility

NCT02314741
View directory record Official record
Conditions
Achalasia
Interventions
POEM Procedure
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2018 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Different Feeding Methods After Pyloromyotomy

NCT01509417
View directory record Official record
Conditions
Emesis
Interventions
ad lib feedings after pyloromyotomy, FLAP diet after pyloromyotomy
Other
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Day to 3 Months
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 28, 2013 · Synced Sep 6, 2026, 5:32 AM EDT
Terminated Not applicable Interventional Results available

A Study to Evaluate Safety and Effectiveness of G-POEM for Gastroparesis

NCT04869670
View directory record Official record
Conditions
Gastroparesis
Interventions
Gastric peroral endoscopic myotomy., Sham Gastric peroral endoscopic myotomy.
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 6, 2026, 5:32 AM EDT
Active, not recruiting Not applicable Interventional

Endoscopic Myotomy of the Pylorus To Improve Emptying and Symptoms Trial

NCT05039424
View directory record Official record
Conditions
Gastroparesis
Interventions
Endoscopic per-oral pyloromyotomy (POP), Diagnostic esophagogastroduodenoscopy (EGD) without pyloric disruption
Procedure
Lead sponsor
Matthew Allemang
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 6, 2026, 5:32 AM EDT
Recruiting No phase listed Observational

Gastroparesis Outcome Longitudinal Database Enrolled Numerically

NCT03876288
View directory record Official record
Conditions
Gastroparesis
Interventions
GI Neuromodulation, Immunotherapy, Pyloric Therapies
Device · Drug · Procedure
Lead sponsor
University of Louisville
Other
Eligibility
Not listed
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2028
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Changes in Cerebral Oxygenation During Laparoscopic Pyloromyotomy

NCT03650842
View directory record Official record
Conditions
Pyloric Stenosis
Interventions
Near infrared spectroscopy (NIRS)
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 5, 2019 · Synced Sep 6, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Endoscopic Pyloromyotomy for Refractory Gastroparesis

NCT03356067
View directory record Official record
Conditions
Gastroparesis
Interventions
Gastric endoscopic peroral pyloromyotomy, Esophago-gastro-duodenoscopy
Procedure
Lead sponsor
Institute for Clinical and Experimental Medicine
Government
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Sep 6, 2026, 5:32 AM EDT
Completed No phase listed Observational Results available

Institutional Audit of the Use of Intravenous Acetaminophen in Infants Undergoing Pyloromyotomy

NCT02359305
View directory record Official record
Conditions
Pyloric Stenosis
Interventions
Acetaminophen
Drug
Lead sponsor
Arlyne Thung
Other
Eligibility
Not listed
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Sep 6, 2026, 5:32 AM EDT
Terminated Not applicable Interventional Results available

Conventional Direct Laryngoscopy Vs. Video Laryngoscopy With The C-MAC For Pyloromyotomy

NCT02775214
View directory record Official record
Conditions
Pyloric Stenosis, Intubation, Pediatric
Interventions
Video Laryngoscopy
Device
Lead sponsor
Indiana University
Other
Eligibility
Up to 6 Months
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Sep 6, 2026, 5:32 AM EDT