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Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Pathophysiology of Orthostatic Intolerance

NCT00608725
Conditions
Tachycardia, Postural Orthostatic Tachycardia Syndrome
Interventions
DAXOR, QSweat, Intrinsic Heart Rate
Radiation · Procedure · Drug
Lead sponsor
Satish R. Raj
Other
Eligibility
18 Years to 80 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Autonomic Nervous System Diseases, Orthostatic Hypotension, Dopamine Beta-Hydroxylase Deficiency, Orthostatic Intolerance
Interventions
Standing or upright tilt, Microneurography, QSweat, neck cuff stimulation, phenylephrine,isoproterenol,nitroprusside,propranolol,edrophonium,atropine,tyramine, clonidine,yohimbine,metoclopramide,alpha-methyldopa, BodPod, Eye exam, Sleep study, Pain response testing, Metabolic chamber, Brain function studies, Bicycle Exercise Test
Procedure · Device · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
12 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee