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Showing 25–44 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Quadratus lumborum block Clear all
Recruiting Phase 4 Interventional

QL Block in Laparoscopic Myomectomy

NCT05979493
View directory record Official record
Conditions
Postoperative Pain, Fibroid Uterus
Interventions
Bupivacain, Saline
Drug
Lead sponsor
Joseph Findley MD
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Beachwood, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Phase 4 Interventional Results available

QL Block With Exparel in Colectomy

NCT03827291
View directory record Official record
Conditions
Laparotomy, Colectomy
Interventions
Exparel, Thoracic epidural analgesia
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

QL vs LP Blocks for Analgesia Following THA

NCT04402437
View directory record Official record
Conditions
Surgery
Interventions
LP Block, QL Block
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 28, 2026, 9:01 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Impact of Quadratus Lumborum Block on Recovery Profile After Ventral Hernia Repair

NCT03794882
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use
Interventions
Quadratus Lumborum Block, Standard Medical Management
Combination Product · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Not applicable Interventional Results available

QL vs PENG for Analgesia After Hip Arthroplasty

NCT05710107
View directory record Official record
Conditions
Block, Hip Replacement, Postoperative Pain
Interventions
PENG + LFC Block, QL Block
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Sep 28, 2026, 9:01 PM EDT
Withdrawn Phase 4 Interventional

Volume vs Concentration: Quadratus Lumborum Blocks With High Volume/Low Concentration or Low Volume/ High Concentration in Nephrectomies

NCT04077398
View directory record Official record
Conditions
Analgesia, Postoperative Pain, Block
Interventions
Ropivacaine 0.5% Injectable Solution
Drug
Lead sponsor
Bruce Ben-David
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Sep 28, 2026, 9:01 PM EDT
Withdrawn Phase 4 Interventional

Rescue Quadratus Lumborum Blocks for Post-cesarean Pain

NCT04397458
View directory record Official record
Conditions
Morphine, Analgesics, Analgesics, Opioid, Peripheral Nervous System Agents
Interventions
Saline, Bupivacaine, Dexamethasone
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Sep 28, 2026, 9:01 PM EDT
Recruiting Not applicable Interventional

Efficacy of Perioperative Opioid Sparing Techniques on Time to Initiation of Chemotherapy

NCT07153614
View directory record Official record
Conditions
Perioperative Opioid Sparing Techniques
Interventions
Intrathecal Morphine Block, Bilateral Quadratus Lumborum Block, Bilateral Transverse Abdominis Plane Block
Procedure
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Quadratus Lumborum Block Versus Transversus Abdominus Plane Block for Pain Management After Donor Nephrectomy

NCT03476850
View directory record Official record
Conditions
Kidney Donor
Interventions
QL Block, TAP Block
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Sep 28, 2026, 9:01 PM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Lidocaine Infusion or Quadratus Lumborum Block and Intrathecal Morphine, Versus Intrathecal Morphine Alone

NCT03658109
View directory record Official record
Conditions
Gynecologic Cancer
Interventions
Lidocaine Bolus Infusion, QL block, Saline Bolus Infusion, Simulated QL block
Drug · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 69 Years · Female only
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 9, 2021 · Synced Sep 28, 2026, 9:01 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Quadratus Lumborum vs Erector Spinae Supplementary Blocks With Lumbar Plexus Blocks for Hip PAO

NCT04481451
View directory record Official record
Conditions
Pain, Postoperative, Regional Anesthesia, Hip Dysplasia
Interventions
Erector spinae block with ropivacaine 0.2%, Quadratus lumborum block with ropivacaine 0.2%, Ropivacaine
Procedure · Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
15 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 28, 2026, 9:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

ESP vs QL for Total Abdominal Hysterectomy

NCT04074226
View directory record Official record
Conditions
Postoperative Pain
Interventions
Erector Spinae Plane block, Quadratus Lumborum Block
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Phase 4 Interventional Results available

The Role of Quadratus Lumborum Blocks Following Minimally Invasive Hysterectomy

NCT05480111
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Local anesthesia at incision site, Sham QL, Sham Local, QL
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Phase 4 Interventional Results available

Efficacy Of Quadratus Lumborum II Block For Laparoscopic Sleeve Gastrectomy

NCT04073056
View directory record Official record
Conditions
Morbid Obesity, High BMI
Interventions
Bupivacaine
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Phase 4 Interventional Results available

Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement

NCT03801265
View directory record Official record
Conditions
Hip Osteoarthritis
Interventions
Lumbar plexus block, Quadratus lumborum type 3 block, Ropivacaine injection
Procedure · Drug
Lead sponsor
Sharad Khetarpal
Other
Eligibility
18 Years to 90 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Quadratus Lumborum Block for Analgesia Following Hip Arthroscopy

NCT03557125
View directory record Official record
Conditions
Surgery
Interventions
QL Block, Saline Skin Wheel
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Quadratus Lumborum Block Versus Control for Total Hip Arthroplasty

NCT03408483
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
Quadratus Lumborum Block (QLB), Standard of Care
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Sep 28, 2026, 9:01 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain

NCT04368364
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Intrathecal morphine sulfate (ITM), Bupivacaine hydrochloride, ropivacaine hydrochloride
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2022 · Synced Sep 28, 2026, 9:01 PM EDT
Terminated Phase 3 Interventional Results available

Comparison of Quadratus Lumborum Block Types

NCT04588389
View directory record Official record
Conditions
Pain, Opioid Use, Lumbar Disc Herniation
Interventions
Ropivacaine injection Location 1, Ropivacaine injection Location 2, Multimodal Pharmacological Management
Drug
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
40 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Sep 28, 2026, 9:01 PM EDT
Completed Phase 3 Interventional Results available

Comparing Liposomal Bupivacaine Versus Standard Bupivacaine in Colorectal Surgery

NCT03702621
View directory record Official record
Conditions
Colorectal Surgery
Interventions
liposomal Bupivacaine, Bupivacaine Hydrochloride
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Sep 28, 2026, 9:01 PM EDT