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ClinicalTrials.gov public records Last synced Sep 10, 2026, 5:54 PM EDT

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Showing 1–24 of 263 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Quality of Life measures Clear all
Enrolling by invitation No phase listed Observational

Effect of Treatment Modality on Psychosocial Functioning of Survivors of Unilateral Retinoblastoma

NCT03662776
View directory record Official record
Conditions
Survivors of Unilateral Retinoblastoma
Interventions
BASC-3 survey, PROMIS survey
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
8 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
2
States / cities
New York, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2026 · Synced Sep 10, 2026, 5:54 PM EDT
Active, not recruiting Not applicable Interventional Results available

Sickle Cell Disease (SCD) Bone Pain Study

NCT05283148
View directory record Official record
Conditions
Sickle Cell Disease, Sickle Cell Anemia, Low Bone Density, Osteoporosis, Osteopenia, Vertebral Fracture, Vertebral Compression, Osteonecrosis, Ischemic Necrosis, Avascular Necrosis
Interventions
Dual-energy X-ray absorptiometry, Vertebral fracture analysis, Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Sep 10, 2026, 5:54 PM EDT
Completed Not applicable Interventional

Pelvic Physical Therapy for Sexual Dysfunction in Gynecologic Oncology Survivors

NCT05242770
View directory record Official record
Conditions
Gynecologic Cancer, Sexual Dysfunction
Interventions
Control Arm, Physical Therapy Arm, European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30), Female Sexual Function Index (FSFI), Exit Interview
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 10, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

Implementing BREASTChoice Into Practice

NCT04491591
View directory record Official record
Conditions
Breast Reconstruction, Breast Cancer
Interventions
Breast Reconstruction Education and Support Tool (BREASTChoice), Attention Control Website, Clinician Survey
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
St Louis, Missouri • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2024 · Synced Sep 10, 2026, 5:54 PM EDT
Completed No phase listed Observational

Assessment of Patterns of Patient Reported Outcomes in Adults With Congenital Heart Disease - International Study II

NCT04902768
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
This is an observational study, there is no intervention
Other
Lead sponsor
KU Leuven
Other
Eligibility
18 Years and older
Enrollment
8,415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
10
States / cities
San Francisco, California • Stanford, California • Gainesville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 10, 2026, 5:54 PM EDT
Recruiting Not applicable Interventional

Evaluating Whether a Nausea Band Reduces Symptoms in Those With Chronic Nausea Vomiting

NCT07720323
View directory record Official record
Conditions
Chronic Nausea, Chronic Nausea and Vomiting Syndrome
Interventions
EmeTerm wearable TENS device
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 10, 2026, 5:54 PM EDT
Completed Phase 3 Interventional Results available

Reducing Diagnostic Error to Improve Patient Safety in COPD and Asthma (REDEFINE Study)

NCT03137303
View directory record Official record
Conditions
COPD Asthma
Interventions
Spirometry at initial visit, Albuterol, Spirometry at 12-month follow-up
Device · Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
40 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced Sep 10, 2026, 5:54 PM EDT
Completed Not applicable Interventional

Comparing Distress Screening + Consultation With Enhanced Usual Care for Caregivers of Cancer Patients

NCT03856086
View directory record Official record
Conditions
Cancer Caregivers
Interventions
Baseline questionnaire, NCCN Problem List, FACT-GP, HADS, CSS-CG
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 10, 2026, 5:54 PM EDT
Completed Not applicable Interventional

Home COPD and Open Ventilation Evaluation (HOPE) Study

NCT03691181
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Ventilation
Device
Lead sponsor
Landon Pediatric Foundation
Other
Eligibility
40 Years to 100 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2018 · Synced Sep 10, 2026, 5:54 PM EDT
Active, not recruiting Phase 2 Interventional

Hyperpolarized Xenon-129 MRI: a New Multi-dimensional Biomarker to Determine Pulmonary Physiologic Responses to COPD Therapeutics

NCT03002389
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Anoro Ellipta, Arnuity Ellipta
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 85 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Keswick, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 17, 2024 · Synced Sep 10, 2026, 5:54 PM EDT
Completed No phase listed Observational

Targeted Literature Review and Subject Interviews in Wiskott-Aldrich Syndrome (WAS)

NCT03399461
View directory record Official record
Conditions
Wiskott-Aldrich Syndrome
Interventions
Patient Interview guide, Caregiver interview guide, Sociodemographic questionnaire, Pediatric quality of life (PedsQL) questionnaire, Clinical questionnaire
Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
12 Years to 30 Years · Male only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Collegeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Sep 10, 2026, 5:54 PM EDT
Active, not recruiting No phase listed Observational

Quality of Life in Patients With Bladder Cancer

NCT00745355
View directory record Official record
Conditions
Bladder Cancer
Interventions
Quality Of Life questionnaires
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 10, 2026, 5:54 PM EDT
Recruiting Phase 2 Interventional

Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score

NCT02476786
View directory record Official record
Conditions
Breast Cancer, Cancer of Breast, Breast Neoplasms, Cancer of the Breast
Interventions
FACT-B, Goserelin, Anastrozole, Exemestane, Fulvestrant, Tamoxifen, Archived tissue collection
Behavioral · Drug · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
70 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2032
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 10, 2026, 5:54 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1

NCT00853580
View directory record Official record
Conditions
Neurofibromatosis Type 1
Interventions
Lovastatin ™, placebo
Drug · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
8 Years to 15 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
11
States / cities
Birmingham, Alabama • Los Angeles, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated Mar 11, 2018 · Synced Sep 10, 2026, 5:54 PM EDT
Withdrawn Not applicable Interventional

Breast Reconstruction Following Breast Cancer in Very High Risk Patients

NCT03261323
View directory record Official record
Conditions
Breast Cancer, Malignant Neoplasm of Breast
Interventions
Immediate Breast Reconstruction, Delayed Breast Reconstruction, Breast-Q questionnaire
Procedure · Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
19 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Sep 10, 2026, 5:54 PM EDT
Withdrawn Not applicable Interventional

Sensation, Motion, and Quality of Life on Natalizumab and Off Natalizumab

NCT05172466
View directory record Official record
Conditions
Relapsing-remitting Multiple Sclerosis (RRMS)
Interventions
BeCare application
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 24, 2022 · Synced Sep 10, 2026, 5:54 PM EDT
Completed No phase listed Observational

Interventional Validation of an MDS-Specific Measure of Quality of Life: Assessing the Responsiveness of the Quality of Life in Myelodysplasia Scale (QUALMS-1) to Different Hypomethylating Agent Regimens for Low and Intermediate Risk Disease

NCT02378701
View directory record Official record
Conditions
Leukemia
Interventions
QUALMS-1 Questionnaire, FACT-An Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
6
States / cities
Tampa, Florida • Baltimore, Maryland • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Sep 10, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

Deployment of American Heart Association Heart Failure Protocols and Content Within the Intel® Health Guide System

NCT01275846
View directory record Official record
Conditions
Heart Failure
Interventions
Health Guide using AHA heart failure protocols and content
Device
Lead sponsor
American Heart Association
Other
Eligibility
Not listed
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Warrensville Heights, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Sep 10, 2026, 5:54 PM EDT
Not listed No phase listed Observational

Creation of Home-based Asthma Real-World Measures With Mobile Health Study

NCT04462224
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Sep 10, 2026, 5:54 PM EDT
Recruiting No phase listed Observational

PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery

NCT06089083
View directory record Official record
Conditions
Malignant Female Reproductive System Neoplasm, Gynecologic Cancer, Gynecologic Neoplasm
Interventions
Physical function assessment, Self-reported Assessments and Questionnaires, Surgery (Standard of Care, Non-Interventional)
Other · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
2
States / cities
San Francisco, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 10, 2026, 5:54 PM EDT
Recruiting Phase 2 Interventional

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

NCT05307939
View directory record Official record
Conditions
HPV, Oropharynx Cancer, HPV-Related Carcinoma, HPV-Related Malignancy, HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions
HPV ctDNA Assay, MRI Studies, EORTC QLQ H&N 35 and C30, MDADI-HN, COST-FACIT, Intensity-Modulated Radiation Therapy (Arm A), Chemoradiation (Arm B)
Diagnostic Test · Behavioral · Radiation + 1 more
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
8
States / cities
Miami, Florida • Basking Ridge, New Jersey • Middletown, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 10, 2026, 5:54 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Optimizing Health Related Quality of Life Measurement in Adolescent and Young Adult Oncology

NCT06897137
View directory record Official record
Conditions
Malignant Solid Neoplasm, Hematopoietic Neoplasms, Lymphatic System Neoplasm
Interventions
Surveys/Questionnaires
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
15 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 10, 2026, 5:54 PM EDT
Completed Not applicable Interventional Results available

Technology-Supported Physical Activity Intervention for Metastatic Breast Cancer Survivors: Fit2ThriveMB

NCT04129346
View directory record Official record
Conditions
Metastatic Breast Cancer, Obesity
Interventions
Fit2ThriveMB App, Fitbit, Physical Activity Coaching Calls, Healthy Living Coaching Calls, Cancer.net app
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 9, 2022 · Synced Sep 10, 2026, 5:54 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

A Study to Measure the Degree and Effectiveness of the Various vSculpt Operating Modes

NCT02856490
View directory record Official record
Conditions
Sexual Dysfunction, Stress Incontinence
Interventions
vSculpt, InTone
Device
Lead sponsor
Joylux, Inc.
Other
Eligibility
48 Years to 60 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Sep 10, 2026, 5:54 PM EDT