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ClinicalTrials.gov public records Last synced Oct 21, 2026, 3:46 PM EDT

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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
Conditions
Fibromyalgia
Interventions
Prolonged Nightly Fasting, Health Education Control
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Head and Neck Cancer
Interventions
Questionnaires, Quantitative Sensory Testing
Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
838 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
2
States / cities
Houston, Texas
Conditions
Sensation Disorders, Sensation, Phantom, Pain, Postoperative, Pain, Chronic, Numbness, Sensory Disorder, Sensory Defect, Phantom Pain, Phantom Sensation
Interventions
Sensory testing
Diagnostic Test
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2033
U.S. locations
2
States / cities
Boston, Massachusetts • New York, New York
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Exploring Pain Modulation With TMS and Repeated Pain Conditioning in Healthy Individuals

NCT06726018
Conditions
Healthy Adult
Interventions
Conditioned Pain Modulation (CPM)
Behavioral
Lead sponsor
Priyanka Rana, PT, MPT, PhD
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
El Paso, Texas
Conditions
Genotype, Pain, Genetic Variation, Quantitative Sensory Testing (QST), GCH1
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 99 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Neuropathy;Peripheral
Interventions
Abbott® DRG / Abbott®/Medtronic® SCS, Control Group
Device · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Measuring Attention During Immersive Virtual Reality Distraction

NCT06615245
Conditions
Distraction
Interventions
No VR vs. immersive high tech VR, Plausible control vs immersive High Tech VR
Behavioral
Lead sponsor
Hunter Hoffman
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Intellectual Disability
Interventions
TSA2 Thermosensory Stimulator
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
8 Years to 30 Years
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Radiculopathy, Lower Extremity Radicular Pain
Interventions
Quantitative Sensory Testing (QST), Epidural Steroid Injection (ESI)
Device · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Impact of Cerebellar Mass Resection on Pain Processing

NCT02261649
Conditions
Cerebellar Neoplasm
Interventions
Medoc Advanced Medical Systems PATHWAY Model ATS, Cold water bath, MRI scanner, Questionnaires
Device · Procedure · Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
6 Years to 38 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Waltham, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Music Therapy on Nociceptive Processing

NCT03692247
Conditions
Pain, Chronic Pain
Interventions
Smartphone-based Music Intervention
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Brookline, Massachusetts
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Explosive Synchronization of Brain Network Activity in Chronic Pain

NCT04606095
Conditions
Fibromyalgia, Healthy Volunteers
Interventions
EEG, Neuroimaging EEG/fMRI (Aim 1), HD-tDCS treatments, Sham HD-tDCS treatments, Neuroimaging EEG/fMRI (Aim 3)
Diagnostic Test · Device
Lead sponsor
University of Michigan
Other
Eligibility
19 Years to 74 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Diabetic Polyneuropathy, Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetes Complications
Interventions
Exposure: Corneal nerve fibre morphology by the CCM Procedure
Other
Lead sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Other
Eligibility
18 Years and older
Enrollment
624 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Results available

Peripheral Sensory Input in Central Post Stroke Pain (CPSP)

NCT02148588
Conditions
Central Post Stroke Pain
Interventions
Ultrasound-guided peripheral nerve block with 2% lidocaine
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Recruiting Not applicable Interventional Accepts healthy volunteers

Pain in Aging Former Athletes, Master's Athletes, and Nonathletes

NCT07502742
Conditions
Pain, Pain Management, Athlete, Exercise Training, Sports Medicine, Strength Training Effects, Aerobic Exercise, Strength Training, Aging, Quality of Life, Sports
Interventions
Moderate-Intensity Strength Exercise Intervention, Moderate-Intensity Aerobic Exercise Intervention
Other
Lead sponsor
Marquette University
Other
Eligibility
35 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Pain, Pain, Neuropathic
Interventions
Neurodynamic Slider Mobilization, Neurodynamic Tensioner Mobilization, Sham Neurodynamic Mobilization
Other
Lead sponsor
Brenau University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Gainesville, Georgia
Conditions
Parkinson's Disease, Tourette's Syndrome, Tic Disorders, Dystonia, Movement Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Eye-tracking Device, Pulsed vibrator, Gait Trainer Treadmill (GTT), Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA, iMobility, QMAT, Treadmill Test, Arm Intellistretch Device, Transcranial Sonography (TCS), Behavioral tasks, TMS single/paired pulse, MEG, EEG, MRI techniques, Peripheral Nerve Stimulation, EMG, Trancutaneous spinal direct current stimulation (tsDCS)
Procedure · Device · Other + 1 more
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
1,273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Chronic Pancreatitis, Chronic Pain
Interventions
Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
Diagnostic Test
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
3
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Pittsburgh, Pennsylvania
Completed Not applicable Interventional

Cordotomy for Refractory Cancer Pain

NCT02345629
Conditions
Advanced Cancers, Pain
Interventions
Cordotomy, Pain/Symptom Questionnaire, Sharpness Sensory Testing, Heat Pain Sensory Testing
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Generalized Hypersensitivity in Patients With Fibromyalgia Syndrome

NCT04415866
Conditions
Fibromyalgia
Interventions
Paced Auditory Serial Addition task (PASAT)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Sleep Disruption Hyperalgesia

NCT01794689
Conditions
Sleep Deprivation, Pain
Interventions
Morphine, Saline Placebo, Forced Awakenings, Uninterrupted Sleep
Drug · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 48 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Glioblastoma Multiforme, Glioma
Interventions
Thalidomide, CPT-11, MRI Scan, Quantitative Sensory Tests (QST)
Drug · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Houston, Texas
Conditions
Peripheral Neuropathy, Chemotherapy-induced Peripheral Neuropathy
Interventions
Acupuncture, Sham Acupuncture, Usual Care Group, questionnaires
Procedure · Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Commack, New York • New York, New York
Not yet recruiting Not applicable Interventional

Light Bulb Stimuli to Reduce Chronic Pain

NCT07825792
Conditions
Fibromyalgia, Musculoskeletal Pain
Interventions
S-Cone Stimulating Chromatic Light, Equal-Energy White Light
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina