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ClinicalTrials.gov public records Last synced Sep 5, 2026, 5:18 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: RF device Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Subject Evaluation of a 1064nm Diode Laser/RF

NCT04090853
View directory record Official record
Conditions
Subcutaneous Fat Disorder
Interventions
Venus Bliss
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Denver, Colorado • Foxborough, Massachusetts • Woodmere, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2023 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Venous Thrombosis Prevention and Sleep Quality: A Comparison of the Kendall and the Recovery Health MAC Systems

NCT06042686
View directory record Official record
Conditions
Deep Venous Thrombosis of Deep Femoral Vein
Interventions
RF Health MAC Device
Device
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
50 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2023 · Synced Sep 5, 2026, 5:18 PM EDT
Not yet recruiting Not applicable Interventional

Study of the TheraBionic P1 Device in Patients With Metastatic Triple Negative Breast Cancer After Progression

NCT07672431
View directory record Official record
Conditions
Triple Negative Breast Cancer
Interventions
TheraBionic P1
Device
Lead sponsor
Barbara Ann Karmanos Cancer Institute
Other
Eligibility
22 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 5, 2026, 5:18 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Comparing UroLift Experience Against Rezūm

NCT04338776
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
UroLift, Rezum
Device
Lead sponsor
NeoTract, Inc.
Industry
Eligibility
50 Years and older · Male only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
7
States / cities
Los Angeles, California • Royal Oak, Michigan • Garden City, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Not applicable Interventional Results available

Feasibility Study To Collect Safety And Preliminary Efficacy Data For A Radiofrequency Microneedling Device

NCT05254210
View directory record Official record
Conditions
Wrinkles, Fine Lines, Crepey Skin, Acne Scars, Active Acne, Enlarged Pores, Loose Skin
Interventions
RF Device (Potenza™)
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
West Hollywood, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Safety and Efficacy of the Apollo™ System for Treatment of Wrinkles and Rhytides

NCT01283711
View directory record Official record
Conditions
Facelift
Interventions
apollo device
Device
Lead sponsor
Pollogen
Industry
Eligibility
35 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Palm Beach Gardens, Florida
Source: ClinicalTrials.gov public record
Updated May 16, 2013 · Synced Sep 5, 2026, 5:18 PM EDT
Not listed No phase listed Observational

Post Approval NovaSure Essure Labeling Study

NCT01934244
View directory record Official record
Conditions
Menorrhagia
Interventions
NovaSure Endometrial Ablation
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
14
States / cities
Chandler, Arizona • Arvada, Colorado • Sarasota, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2018 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Not applicable Interventional

Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic Subjects

NCT04285554
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
iRF System Hepatic Denervation
Device
Lead sponsor
Metavention
Industry
Eligibility
22 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
8
States / cities
Birmingham, Alabama • Stanford, California • Orlando, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of the ToothWave -12 Weeks Calculus Study

NCT04092075
View directory record Official record
Conditions
Gingivitis, Plaque, Calculus, Dental
Interventions
RF-utilizing powered toothbrush, Control placebo with no RF
Device
Lead sponsor
Home Skinovations Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Sep 5, 2026, 5:18 PM EDT
Active, not recruiting Not applicable Interventional

Study on Using Radiofrequency to Treat Moderate to Severe Acne

NCT06315166
View directory record Official record
Conditions
Moderate to Severe Acne Vulgaris
Interventions
triLift/Legend Pro+ Fractional RF System
Device
Lead sponsor
Pollogen
Industry
Eligibility
18 Years to 25 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Grosse Pointe, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Phase 1 Interventional

RF Ablation of Atrial Fibrillation

NCT00265629
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
RF catheter ablation
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Not applicable Interventional Results available

Wire Instrumentation Using Radiofrequency Energy to Impact Transseptal Efficiency

NCT04645342
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Baylis Versacross RF wire, Baylis RF needle
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Sep 5, 2026, 5:18 PM EDT
Not listed Not applicable Interventional

Clinical Study to Evaluate Alexandrite Laser for the Treatment of Acne Scars

NCT04807179
View directory record Official record
Conditions
Acne Scars
Interventions
Experimental: RF Device Arm
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Los Angeles, California • New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Sep 5, 2026, 5:18 PM EDT
Terminated Not applicable Interventional Results available

Radio Frequency (RF) Device for Reduction in Size of Localized Areas of the Body

NCT00953160
View directory record Official record
Conditions
Cellulite
Interventions
Cutera Radio Frequency Device
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
5
States / cities
Danville, California • Dublin, California • Sacramento, California + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2023 · Synced Sep 5, 2026, 5:18 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System

NCT06157567
View directory record Official record
Conditions
Skin Laxity, Wrinkle, Skin Condition
Interventions
Profound Matrix
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
4
States / cities
Jacksonville, Florida • Marlborough, Massachusetts • Fayetteville, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 5, 2026, 5:18 PM EDT
Not listed Phase 3 Interventional

Clinical Trial of the SonRtip Lead and Automatic AV-VV Optimization Algorithm in the PARADYM RF SonR CRT-D

NCT01534234
View directory record Official record
Conditions
Heart Failure NYHA Class III and Ambulatory IV
Interventions
PARADYM RF SONR
Device
Lead sponsor
MicroPort CRM
Industry
Eligibility
18 Years and older
Enrollment
1,039 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
31
States / cities
Birmingham, Alabama • Phoenix, Arizona • Culver City, California + 21 more
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Sep 5, 2026, 5:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies

NCT02120625
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar MB RFN
Device
Lead sponsor
Nimbus Concepts, LLC
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Greenwood Village, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Early Feasibility Study of the SENSE Device

NCT03827720
View directory record Official record
Conditions
Hemorrhagic Stroke, Ischemic Stroke
Interventions
SENSE Device
Device
Lead sponsor
Sense Diagnostics, LLC
Industry
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multi-Center Pilot Study of Cutera truSculpt Device

NCT03782545
View directory record Official record
Conditions
Treatment for Cellulite on the Stomach and Flanks
Interventions
Cutera truSculpt Device
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
3
States / cities
Sacramento, California • Glencoe, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 5, 2026, 5:18 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Electrical Muscle Stimulation with 1064 Nm Diode Laser and RF/PEMF for Non-invasive Body Contouring and Fat Reduction.

NCT05256771
View directory record Official record
Conditions
Fat Reduction, Muscle Tone Increased
Interventions
EMS, 1064 nm diode laser, RF/PEMF
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
3
States / cities
San Diego, California • Hackensack, New Jersey • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Sep 5, 2026, 5:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study to Test the SENSE Device in Military-Age Patients With Traumatic Brain Injury

NCT05155800
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
SDx3
Device
Lead sponsor
Sense Diagnostics, LLC
Industry
Eligibility
22 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Atlanta, Georgia • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Sep 5, 2026, 5:18 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Radio-Frequency Microneedling Device

NCT06228144
View directory record Official record
Conditions
Healthy
Interventions
Candela Profound System with Dermal Handpiece, Experimental Dermal Cooling Device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 5, 2026, 5:18 PM EDT
Completed No phase listed Observational

Connecting Audio and Radio Sensing Systems to Improve Care at Home

NCT05344950
View directory record Official record
Conditions
Colorectal Cancer, Bladder Cancer, Ovarian Cancer, Cervical Cancer, Uterine Cancer
Interventions
Audio + Radio (AURA)
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Chapel Hill, North Carolina • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 5, 2026, 5:18 PM EDT
Completed Not applicable Interventional

Safety and Efficacy of Transcranial Electromagnetic Treatment Against Alzheimer's Disease

NCT02958930
View directory record Official record
Conditions
Alzheimer Disease, Alzheimer Disease, Late Onset
Interventions
MemorEM 1000
Device
Lead sponsor
NeuroEM Therapeutics, Inc.
Industry
Eligibility
63 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Sep 5, 2026, 5:18 PM EDT