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ClinicalTrials.gov public records Last synced Oct 27, 2026, 12:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 388 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: RFA Clear all
Recruiting Not applicable Interventional

Low Voltage-Directed Catheter Ablation for Atrial Fibrillation

NCT03355456
View directory record Official record
Conditions
Atrial Fibrillation - Symptomatic
Interventions
Radiofrequency ablation
Procedure
Lead sponsor
Ohad Ziv
Other
Eligibility
18 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 27, 2026, 12:56 AM EDT
Completed No phase listed Observational

The Relative Prevalence and Severity of Autonomic Nervous System Dysfunction

NCT00919347
View directory record Official record
Conditions
Cardiovascular Autonomic Neuropathy, Diabetic Autonomic Neuropathy, Autonomic Dysfunction
Interventions
ANSAR ANX 3.0 Software
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 28, 2012 · Synced Oct 27, 2026, 12:56 AM EDT
Withdrawn Not applicable Interventional

Feasibility of Ultra-sound Guided Radiofrequency Ablation in the Management of Head and Neck Neoplasia.

NCT00381225
View directory record Official record
Conditions
Head and Neck Neoplasia
Interventions
Ultra-sound guided radio-frequency ablation
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2017 · Synced Oct 27, 2026, 12:56 AM EDT
Completed Not applicable Interventional Results available

SMART Clinical Study: Surgical Multi-center Assessment of RF Ablation for the Treatment of Vertebrogenic Back Pain

NCT01446419
View directory record Official record
Conditions
Low Back Pain
Interventions
Intracept Treatment, Sham Treatment
Device
Lead sponsor
Relievant Medsystems, Inc.
Industry
Eligibility
25 Years to 70 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
13
States / cities
Phoenix, Arizona • Daly City, California • Long Beach, California + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Oct 27, 2026, 12:56 AM EDT
Active, not recruiting Not applicable Interventional

Monopolar Current Cutting Knife vs Bipolar RFA Knife

NCT04919824
View directory record Official record
Conditions
Gastrointestinal Neoplasms
Interventions
Endoscopic Submucosal Dissection, Endoscopic Mucosal Resection
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 27, 2026, 12:56 AM EDT
Terminated Not applicable Interventional

Endorotor Resection In Refractory Barrett's Dysplasia Patients

NCT03364114
View directory record Official record
Conditions
Barrett's Esophagus With Dysplasia
Interventions
EndoRotor Mucosal Resection System, Continued Ablation
Device
Lead sponsor
Interscope, Inc.
Industry
Eligibility
30 Years to 89 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 27, 2026, 12:56 AM EDT
Completed Not applicable Interventional Results available

Irrigated Ablation System Evaluation for Atrial Fibrillation (AF)

NCT01056328
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
SJM Irrigated Cardiac Ablation System, FDA approved Open Irrigated RF Ablation System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
27
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 22 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Oct 27, 2026, 12:56 AM EDT
Completed Phase 2 Interventional Results available

Assess the Efficacy of Pembrolizumab Plus Radiotherapy or Ablation in Metastatic Colorectal Cancer Patients

NCT02437071
View directory record Official record
Conditions
Metastatic Colorectal Cancer
Interventions
Pembrolizumab, Radiotherapy, Radiofrequency ablation
Drug · Radiation · Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 27, 2026, 12:56 AM EDT
Terminated Not applicable Interventional

Radiofrequency (RF) Ablation for Atrial Fibrillation (AF) in Patients With Heart Failure With Preserved Ejection Fraction

NCT04327596
View directory record Official record
Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
RF ablation of AF using CARTO 3 and a Thermocool ST SF ablation catheter
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
50 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Oct 27, 2026, 12:56 AM EDT
Recruiting No phase listed Observational

Post-Market Real-World Evidence Registry for the NeuroOne OneRF® Ablation System for Epilepsy

NCT07546253
View directory record Official record
Conditions
Drug Resistant Epilepsy, Refractory Epilepsy
Interventions
Participants are not assigned an intervention as part of the study.
Other
Lead sponsor
NeuroOne Medical Technologies Corporation
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Miami, Florida • Livingston, New Jersey • New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 27, 2026, 12:56 AM EDT
Completed No phase listed Observational

Characterization of the Neo-squamous Epithelial Barrier

NCT03077594
View directory record Official record
Conditions
Barrett's Esophagus With Dysplasia
Interventions
Mucosal Impedance, Research Biopsies, Volumetric Laser Endomicroscopy
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
2
States / cities
Rochester, Minnesota • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 18, 2023 · Synced Oct 27, 2026, 12:56 AM EDT
Completed Phase 3 Interventional

Ablation of Clinical Ventricular Tachycardia Versus Addition of Substrate Ablation on the Long Term Success Rate of VT Ablation

NCT01045668
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Radiofrequency Catheter Ablation (RFCA)
Procedure
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2014 · Synced Oct 27, 2026, 12:56 AM EDT
Completed No phase listed Observational

Barrett's Esophagus & Gastroesophageal Reflux Disease

NCT00513331
View directory record Official record
Conditions
Barrett's Esophagus, GERD
Interventions
Endoscopy, Radiofrequency ablation protocol, Endoscopic mucosal resection protocol
Procedure
Lead sponsor
Valley Health System
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 1, 2014 · Synced Oct 27, 2026, 12:56 AM EDT
Completed Not applicable Interventional

SERF VT Ablation Early Feasibility Study (EFS)

NCT03628534
View directory record Official record
Conditions
Ventricular Tachycardia, Arrythmia, Heart Diseases, Cardiovascular Diseases
Interventions
Saline Enhanced Radiofrequency (SERF) ablation
Device
Lead sponsor
Thermedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
Maywood, Illinois • Rochester, Minnesota • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Oct 27, 2026, 12:56 AM EDT
Withdrawn Early Phase 1 Interventional

Comparison of Ventricular Tachycardia Ablation Strategies in Patients With Ischemic Cardiomyopathy

NCT04512911
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Endocardial ablation, Endocardial- Epicardial ablation, Antiarrhythmic medications
Procedure · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 27, 2026, 12:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

CARTO® 3 System and Real Time Intracardiac Ultrasound

NCT01716663
View directory record Official record
Conditions
Atrial Fibrillation, Paroxysmal AF
Interventions
Catheter Ablation
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
26
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Santa Barbara, California + 23 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2014 · Synced Oct 27, 2026, 12:56 AM EDT
Completed Phase 3 Interventional Results available

Endoscopic Biliary Co-axial Stent Placement Plus/Minus Use of Radiofrequency Ablation (RFA) for Clearance of Occluded Self Expandable Metal Stents (SEMS) in Patients With Distal Biliary Obstruction From Unresectable Biliary-pancreatic Malignancies

NCT02340728
View directory record Official record
Conditions
Pancreatic Cancer, Unresectable Biliary-pancreatic Malignancies
Interventions
ERCP with SEMS plus radiofrequency ablation, ERCP with SEMS alone (standard of care)
Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Oct 27, 2026, 12:56 AM EDT
Withdrawn No phase listed Observational

Preop Cooled Radiofrequency Ablation for Total Knee Replacement

NCT03893292
View directory record Official record
Conditions
Postoperative Pain, Knee Osteoarthritis
Interventions
Total knee replacement, COOLIEF
Procedure · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2020 · Synced Oct 27, 2026, 12:56 AM EDT
Recruiting Not applicable Interventional

Feasibility Study for the SIRA-1000, SIRA® RFA Electrosurgical Device as an Adjunct to Breast Conserving Surgery

NCT07206121
View directory record Official record
Conditions
Breast Cancer, Breast-conserving Surgery, Breast Cancer - Infiltrating Ductal Carcinoma, ER/PR+Her2neu, Grade I, II, III
Interventions
Radiofrequency ablation alone, Radiofrequency ablation Electrosurgical Device
Device
Lead sponsor
Innoblative Designs, Inc.
Industry
Eligibility
50 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 27, 2026, 12:56 AM EDT
Terminated No phase listed Observational

The Intracept Global Registry ( TIGR ) - Pilot Study

NCT04449835
View directory record Official record
Conditions
Low Back Pain
Interventions
Intracept Procedure
Procedure
Lead sponsor
Relievant Medsystems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 5, 2023 · Synced Oct 27, 2026, 12:56 AM EDT
Terminated Not applicable Interventional

Endoscopic Resection or Ablation for Patients With Dysplasia or Cancer Requiring Treatment of Barrett's Esophagus

NCT01572987
View directory record Official record
Conditions
Barrett's Esophagus, Esophageal Neoplasms
Interventions
Radiofrequency Ablation(RFA) by HALO device., Endoscopic mucosal resection(EMR) by mucosectomy kit.
Device
Lead sponsor
Midwest Biomedical Research
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
3
States / cities
Chicago, Illinois • St Louis, Missouri • New York, New York
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 27, 2026, 12:56 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Software-Aided Imaging (Morfeus) for Confirming Tumor Coverage With Ablation in Patients With Liver Tumors, the COVER-ALL Study

NCT04083378
View directory record Official record
Conditions
Malignant Liver Neoplasm
Interventions
Ablation Therapy, Image-Guided Therapy, Quality-of-Life Assessment, Questionnaire Administration
Procedure · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 27, 2026, 12:56 AM EDT
Completed Not applicable Interventional

A Trial of High Power-Short Duration Versus Standard Power-Long Duration Radiofrequency Ablation for Treatment of Atrial Fibrillation

NCT04148664
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation Paroxysmal, Atrial Fibrillation, Persistent
Interventions
Catheter ablation with Standard RF ablation settings, Catheter ablation with High Power Short Duration RF ablation settings
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 27, 2026, 12:56 AM EDT