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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Radiofrequency Ablation Clear all
Enrolling by invitation No phase listed Observational

Endoscopic Ultrasound Radiofrequency Ablation, Database Repository

NCT04693754
View directory record Official record
Conditions
Pancreatic Neoplasm
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
14 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 1, 2026, 7:12 PM EDT
Completed Not applicable Interventional

Cordotomy for Refractory Cancer Pain

NCT02345629
View directory record Official record
Conditions
Advanced Cancers, Pain
Interventions
Cordotomy, Pain/Symptom Questionnaire, Sharpness Sensory Testing, Heat Pain Sensory Testing
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced Sep 1, 2026, 7:12 PM EDT
Terminated Phase 2 Interventional Results available

Effect of Dexlansoprazole 60 mg QD and 60 mg BID on Recurrence of Intestinal Metaplasia in Subjects Who Have Achieved Complete Eradication of Barrett's Esophagus With Radiofrequency Ablation

NCT02162758
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Dexlansoprazole, Dexlansoprazole Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
6
States / cities
Jacksonville, Florida • Chapel Hill, North Carolina • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Sep 1, 2026, 7:12 PM EDT
Completed Phase 4 Interventional Results available

Does Intensive Acid Suppression Reduce Esophageal Inflammation and Recurrent Barrett's Esophagus Following Ablation?

NCT01093755
View directory record Official record
Conditions
Inflammation, Barrett's Esophagus
Interventions
dexlansoprazole, Omeprazole
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Sep 1, 2026, 7:12 PM EDT
Completed No phase listed Observational

Balloon Cryotherapy vs. Radiofrequency Ablation Pain Study

NCT03387982
View directory record Official record
Conditions
Barrett Esophagus
Interventions
Not listed
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
Queens, New York • Danville, Pennsylvania • Charleston, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Sep 1, 2026, 7:12 PM EDT
Completed Phase 2 Interventional

Radiofrequency Ablation in Relieving Pain in Patients With Bones Metastases

NCT00029029
View directory record Official record
Conditions
Metastatic Cancer, Pain
Interventions
pain therapy, radiofrequency ablation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
6
States / cities
Chicago, Illinois • Baltimore, Maryland • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Sep 1, 2026, 7:12 PM EDT
Terminated Not applicable Interventional Results available

Minimally Invasive Prostatic Vapor Ablation for the Treatment of BPH in Large Prostates (Rezūm XL)

NCT03605745
View directory record Official record
Conditions
BPH With Urinary Obstruction, BPH, BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
Interventions
Prostatic Vapor Ablation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
50 Years and older · Male only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
9
States / cities
Scottsdale, Arizona • St. Petersburg, Florida • Jeffersonville, Indiana + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Sep 1, 2026, 7:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Laparoscopic Radiofrequency Ablation (RFA) of Symptomatic Uterine Fibroids

NCT00874029
View directory record Official record
Conditions
Uterine Fibroids, Uterine Myomas
Interventions
Halt Procedure
Device
Lead sponsor
Acessa Health, Inc.
Industry
Eligibility
25 Years and older · Female only
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
9
States / cities
Phoenix, Arizona • Los Angeles, California • Pasadena, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2014 · Synced Sep 1, 2026, 7:12 PM EDT
Enrolling by invitation No phase listed Observational

Measuring Symptom Relief After Radiofrequency Ablation of the Thyroid

NCT05501041
View directory record Official record
Conditions
Thyroid
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Sep 1, 2026, 7:12 PM EDT
Enrolling by invitation Not applicable Interventional

A Randomized Controlled Trial Comparing Posterior Nasal Nerve Ablation Procedures for Chronic Rhinitis

NCT07706595
View directory record Official record
Conditions
Chronic Rhinitis, Non-allergic Rhinitis
Interventions
RhinAer, Neuromark, Clarifix
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 1, 2026, 7:12 PM EDT
Completed Phase 3 Interventional Results available

Medtronic Concomitant Utilization of Radio Frequency for Atrial Fibrillation CURE-AF/Persistent

NCT00506493
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Cardioblate Surgical Ablation System, Surgical RF Ablation
Device · Procedure
Lead sponsor
Medtronic Cardiac Surgery
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
15
States / cities
Phoenix, Arizona • Concord, California • Los Angeles, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 1, 2026, 7:12 PM EDT
Recruiting Not applicable Interventional

Feasibility Study for the SIRA-1000, SIRA® RFA Electrosurgical Device as an Adjunct to Breast Conserving Surgery

NCT07206121
View directory record Official record
Conditions
Breast Cancer, Breast-conserving Surgery, Breast Cancer - Infiltrating Ductal Carcinoma, ER/PR+Her2neu, Grade I, II, III
Interventions
Radiofrequency ablation alone, Radiofrequency ablation Electrosurgical Device
Device
Lead sponsor
Innoblative Designs, Inc.
Industry
Eligibility
50 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 1, 2026, 7:12 PM EDT
Completed Not applicable Interventional Results available

Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach

NCT02393885
View directory record Official record
Conditions
Atrial Fibrillation, Persistent or Longstanding Persistent Atrial Fibrillation
Interventions
AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
15
States / cities
Long Beach, California • Los Angeles, California • Oakland, California + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Sep 1, 2026, 7:12 PM EDT
Recruiting Phase 2 Interventional

Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

NCT06732388
View directory record Official record
Conditions
Barrett Esophagus, Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8, Esophageal Adenocarcinoma
Interventions
Biopsy Procedure, Biospecimen Collection, Endoscopic Procedure, Itraconazole, Placebo Administration, Questionnaire Administration, Radiofrequency Ablation
Procedure · Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
6
States / cities
Kansas City, Kansas • Ann Arbor, Michigan • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 1, 2026, 7:12 PM EDT
Terminated Not applicable Interventional

nContactSurgical Numeris-AF Tethered Coagulation System for Treatment of Persistent & LSP AF

NCT00950092
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Numeris-AF Tethered Coagulation System with VisiTrax
Device
Lead sponsor
nContact Surgical Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Venice, Florida • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 2, 2014 · Synced Sep 1, 2026, 7:12 PM EDT
Completed Phase 3 Interventional Results available

AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial Fibrillation

NCT00560885
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
AtriCure Bipolar System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
9
States / cities
Sacramento, California • Indianapolis, Indiana • Grand Rapids, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2013 · Synced Sep 1, 2026, 7:12 PM EDT
Completed Not applicable Interventional Results available

Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL)

NCT03057548
View directory record Official record
Conditions
Atrial Fibrillation Chronic, Persistent Atrial Fibrillation
Interventions
Cryo or Radiofrequency (RF) Ablation only of Pulmonary Veins, Cryo or RF Ablation of Pulmonary Veins plus Ablation of the PLAW
Procedure
Lead sponsor
Arash Aryana, MD
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 1, 2026, 7:12 PM EDT
Completed No phase listed Observational

Cryotherapy -BEATS-RF Ablation Trial

NCT01882478
View directory record Official record
Conditions
Barrett's Esophagus With Persistent Dysplasia or, Early Esophageal Adenocarcinoma Post Radio Frequency Ablation
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Sep 1, 2026, 7:12 PM EDT
Completed Not applicable Interventional Results available

Comparison of Percutaneous Closure to Manual Compression for Hemostasis

NCT04180540
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Percutaneous Closure, Manual Compression
Device · Other
Lead sponsor
Michael S. Lloyd
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Sep 1, 2026, 7:12 PM EDT
Recruiting Not applicable Interventional

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

NCT07214376
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Hypertension, Vascular Diseases, Cardiovascular Diseases, Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
Interventions
Pulmonary Artery Denervation (PADN), Sham procedure control
Device
Lead sponsor
Pulnovo Medical, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
6
States / cities
Tucson, Arizona • Houma, Louisiana • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 1, 2026, 7:12 PM EDT
Recruiting Phase 2 Interventional

Venous Ethanol for Ventricular Tachycardia

NCT05511246
View directory record Official record
Conditions
Ventricular Tachycardia, Ischemic Cardiomyopathy
Interventions
Venous ethanol, Catheter ablation
Drug · Procedure
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 1, 2026, 7:12 PM EDT
Not listed Phase 4 Interventional

Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS)

NCT03228823
View directory record Official record
Conditions
Ventricular Premature Beats, Contractions, or Systoles, Cardiomyopathies
Interventions
Radiofrequency ablation, Amiodarone (Antiarrhythmic drug)
Procedure · Drug
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
10
States / cities
Los Angeles, California • San Francisco, California • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Sep 1, 2026, 7:12 PM EDT
Withdrawn Phase 4 Interventional

Catheter Ablation for Recently Diagnosed Paroxysmal Atrial Fibrillation

NCT01505296
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Antiarrhythmic drug, Catheter ablation
Drug · Procedure
Lead sponsor
Valley Health System
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 15, 2014 · Synced Sep 1, 2026, 7:12 PM EDT
Terminated No phase listed Observational

Quality of Life in Patients Post Radiofrequency Ablation

NCT00165997
View directory record Official record
Conditions
Radiofrequency Catheter Ablation, Quality of Life, Arrhythmia
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
5 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2013 · Synced Sep 1, 2026, 7:12 PM EDT