Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:51 PM EDT

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Showing 169–192 of 448 matching trials from the live ClinicalTrials.gov search.
Conditions
Head and Neck Neoplasia
Interventions
Ultra-sound guided radio-frequency ablation
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Primary Tumors, Metastatic Tumors
Interventions
Radiofrequency Tumor Ablation
Procedure
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Not listed
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Ventricular Arrythmia
Interventions
Intramural Needle Ablation, Ablation
Device · Procedure
Lead sponsor
Vivek Reddy
Other
Eligibility
15 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Breast Cancer
Interventions
Percutaneous Removal and Margin Ablation
Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Heart Diseases, Arrhythmia, Atrial Fibrillation
Interventions
NAVISTAR® THERMOCOOL® Catheter, Antiarrhythmic drug
Device · Drug
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
13
States / cities
Greenbrae, California • Orlando, Florida • Maywood, Illinois + 9 more
Conditions
Atrial Fibrillation Chronic, Persistent Atrial Fibrillation
Interventions
Cryo or Radiofrequency (RF) Ablation only of Pulmonary Veins, Cryo or RF Ablation of Pulmonary Veins plus Ablation of the PLAW
Procedure
Lead sponsor
Arash Aryana, MD
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Sacramento, California
Conditions
Osteoarthritis, Knee, Pain, Nerve; Lesion
Interventions
genicular nerve diagnostic block with lidocaine (local anesthetic), genicular nerve radiofrequency ablation
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
30 Years to 80 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Results available

VenaSeal Sapheon Closure System Pivotal Study (VeClose)

NCT01807585
Conditions
Great Saphenous Vein (GSV) With Venous Reflux Disease
Interventions
VenaSeal SCS, ClosureFast Radiofrequency Ablation (RFA), Roll-in (VenaSeal SCS)
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
21 Years to 70 Years
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
10
States / cities
Scottsdale, Arizona • San Diego, California • Greenwood Village, Colorado + 7 more
Conditions
Colorectal Neoplasms
Interventions
MEDI6469
Drug
Lead sponsor
Providence Health & Services
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Atrial Fibrillation, Persistent or Longstanding Persistent Atrial Fibrillation
Interventions
AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
15
States / cities
Long Beach, California • Los Angeles, California • Oakland, California + 11 more
Conditions
Barrett's Esophagus, GERD
Interventions
Endoscopy, Radiofrequency ablation protocol, Endoscopic mucosal resection protocol
Procedure
Lead sponsor
Valley Health System
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Paramus, New Jersey
Conditions
Skin Disorders
Interventions
Topical combination therapy
Other
Lead sponsor
Venus Concept
Industry
Eligibility
21 Years to 75 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Newport Beach, California
Conditions
Soft Tissue Neoplasms
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Ventricular Tachycardia, Heart Diseases
Interventions
High power ablation, Standard ablation power
Procedure
Lead sponsor
Federal Research Clinical Center of Federal Medical & Biological Agency, Russia
Government
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Austin, Texas
Conditions
Osteoarthritis of the Knee
Interventions
t-RFA, C-RFA, Control
Procedure
Lead sponsor
Lyman Medical Research Foundation, Inc.
Other
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Coeur d'Alene, Idaho • Spokane, Washington
Completed No phase listed Observational

Bronchial Thermoplasty 10+ Year Study

NCT03243292
Conditions
Asthma
Interventions
Bronchial Thermoplasty
Other
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
6
States / cities
Los Angeles, California • Detroit, Michigan • Saint Paul, Minnesota + 3 more
Terminated Not applicable Interventional Results available

Radiofrequency Ablation for Amiodarone-induced Thyrotoxicosis

NCT03720210
Conditions
Amiodarone-Induced Thyrotoxicosis
Interventions
RFA
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Suspended Not applicable Interventional

PNS vs RFA for Facet Joint Pain

NCT05952518
Conditions
Facet Joint Pain
Interventions
Sprint PNS system, Radiofrequency Ablation
Device · Procedure
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Breast Cancer
Interventions
Radiofrequency Ablation
Device
Lead sponsor
University of Arkansas
Other
Eligibility
50 Years to 100 Years · Female only
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
6
States / cities
Tucson, Arizona • Little Rock, Arkansas • San Diego, California + 3 more
Conditions
Thyroid
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Paroxysmal Atrial Fibrillation
Interventions
FARAPULSE Pulsed Field Ablation System, RadioFrequency and Cryoballoon Ablation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
706 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
34
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 23 more
Conditions
Atrial Fibrillation
Interventions
Cardioblate System Surgical Ablation System, Surgical RF Ablation
Device · Procedure
Lead sponsor
Medtronic Cardiovascular
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
15
States / cities
Phoenix, Arizona • Concord, California • Los Angeles, California + 12 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Renuvion APR Device to Improve the Appearance of Lax Tissue in the Neck and Submental Region

NCT04146467
Conditions
Lax Skin
Interventions
Renuvion APR Device
Device
Lead sponsor
Apyx Medical
Industry
Eligibility
35 Years to 65 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
6
States / cities
San Diego, California • Washington D.C., District of Columbia • Montclair, New Jersey + 3 more
Conditions
Liver Cancer, Metastatic Cancer
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Chicago, Illinois