Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 7, 2026, 6:17 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Radiofrequency ablation of lumbar medial branch nerves. Clear all

Conditions: Low Back Pain
Interventions: Conventional radiofrequency ablation (RFA), Cooled Radiofrequency Ablation (CRFA); Procedure
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 79 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Low Back Pain
Interventions: RFA at 90 degrees Celsius, RFA at 80 degrees Celsius, C-arm guided 20-gauge radiofrequency needle; Procedure · Device
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 199 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Back Pain Without Radiation, Low Back Pain, Lumbar Radiofrequency Neurotomy
Interventions: Parallel placement of 16 gauge electrodes, Perpendicular placement with 22 gauge electrodes; Procedure
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 40 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Chronic Low-back Pain
Interventions: iovera system, Radiofrequency ablation alone; Device
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Chronic Pain
Interventions: Office-based procedure indicated for chronic pain with music, Office-based procedure indicated for chronic pain without music; Procedure
Lead sponsor: Lake Erie College of Osteopathic Medicine; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Wesley Chapel, Florida • Zephyrhills, Florida

Conditions: Chronic Low Back Pain (CLBP)
Interventions: Lumbar radiofrequency ablation with conventional electrodes (LRFA-C), Lumbar radiofrequency ablation with multi-tined electrodes (LRFA-M), Simulated lumbar radiofrequency ablation; Procedure
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 3
States / cities: Atlanta, Georgia • Cleveland, Ohio • Salt Lake City, Utah

Conditions: Low Back Pain, Chronic
Interventions: Iovera Medial Branch Cryoneurolysis, Radiofrequency ablation (RFA); Device · Procedure
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Lumbar Facet Syndrome
Interventions: Cooled Radiofrequency Ablation of Medial Branch Nerves versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome; Procedure
Lead sponsor: University of Utah; Other
Eligibility: 21 Years and older
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Lumbar Spondylosis
Interventions: Radiofrequency ablation of lumbar medial branch nerves.; Procedure
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Chronic Low-back Pain
Interventions: Cooled Radiofrequency, Conventional Radiofrequency; Device
Lead sponsor: Avanos Medical; Other
Eligibility: 21 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 10
States / cities: Washington D.C., District of Columbia • Bloomington, Illinois • New Orleans, Louisiana + 7 more

Conditions: Lumbar Spondylosis
Interventions: Stratus Nimbus Electrosurgical RF Multi-Tined Expandable Electrode, Stryker Venom Radiofrequency Cannula; Device
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Low Back Pain, Facet Joint Pain
Interventions: iovera system, Radiofrequency ablation; Device
Lead sponsor: Medical Pain Management Services, PLLC; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Saratoga Springs, New York

Conditions: Low Back Pain
Interventions: Lumbar medial branch nerve radiofrequency ablation (LRFA), Simulated LRFA with targeted steroid injections, AcTIVE-CBT, TBSCE; Procedure · Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Low Back Pain, Lumbar Radiculopathy
Interventions: Facet intervention, Sacroiliac joint injection, Epidural steroid injection; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 346 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

A Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves for theTreatment of Lumbar Facet Syndrome

Effect of the Temperature Used in Thermal Radiofrequency Ablation

Parallel Versus Perpendicular Technique for Lumbar Medial Branch Radiofrequency Neurotomy

Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain

Effects of Musical Intervention on Patient Pain and Anxiety for Office-based Procedures

A Superiority Trial of Radiofrequency Ablation for Low Back Pain

A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain

A Prospective Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves Versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome

Comparative Effectiveness of Two Different Approaches to Radiofrequency Ablation of Lumbar Medial Branch Nerves

Cooled RFA vs Conventional RFA to Manage Chronic Facetogenic Low Back Pain

RFA Using Multi-Tined Electrodes vs.Traditional Electrodes for Lumbar Spondylosis

Cryoneurolysis for Facet Mediated Chronic Low Back Pain

Selecting Effective Combinations of Treatment for Low Back Pain

Predictive Factors for LBP Interventional Treatment Outcomes