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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:53 PM EDT

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Showing 1–24 of 39 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Real-time fMRI feedback Clear all
Terminated No phase listed Observational Accepts healthy volunteers

fMRI Neurofeedback for Motor Rehabilitation

NCT02089776
View directory record Official record
Conditions
Stroke, fMRI
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Investigating Electroencephalographic Predictors of Default Mode Network Anticorrelation in Healthy Adults

NCT05592600
View directory record Official record
Conditions
Healthy
Interventions
Neurofeedback
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Brain Signal Feedback Paradigm to Enhance Motor Learning After Stroke

NCT02856035
View directory record Official record
Conditions
Stroke
Interventions
Neural feedback plus FES and motor training
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 88 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2020 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Suicide Specific Rumination in Veterans

NCT06481033
View directory record Official record
Conditions
Depression, Suicide, Mood Disorders
Interventions
Real Time fMRI Neurofeedback
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Terminated Not applicable Interventional Results available

Neurofeedback of Amygdala Activity for Post-traumatic Stress Disorder

NCT03574974
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Experimental Feedback, Control Feedback
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional Results available

Neurofeedback During Naturalistic Stimuli to Reduce Craving in Heroin Addiction

NCT07344233
View directory record Official record
Conditions
Opioid Use Disorder, Substance Use Disorder, Heroin Use Disorder
Interventions
Real-time fMRI Neurofeedback, Sham Real-time fMRI Neurofeedback
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 64 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Rt-fMRI Neurofeedback and AH in Schizophrenia

NCT03504579
View directory record Official record
Conditions
Audio Visual Hallucinations, Neurofeedback, Schizophrenia, Superior Temporal Gyrus
Interventions
rt-fMRI neurofeedback
Other
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Brockton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Oct 29, 2026, 4:53 PM EDT
Recruiting Not applicable Interventional

Amygdala Neurofeedback for Depression - Large Scale Clinical Trial

NCT05703256
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Amygdala real-time fMRI neurofeedback, Sham feedback
Device
Lead sponsor
Kymberly Young
Other
Eligibility
18 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Recruiting Not applicable Interventional

Non-Invasive Neurofeedback Training to Alleviate Tinnitus Distress

NCT07788638
View directory record Official record
Conditions
Tinnitus Aggravated, Tinnitus, Tinnitus, Subjective
Interventions
neurofeedback-guided brain connectivity modulation, sham neurofeedback-guided brain connectivity modulation
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke

NCT06598150
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Shoulder Abduction
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Neurofeedback for Tourette Syndrome

NCT01702077
View directory record Official record
Conditions
Tourette Syndrome, Chronic Tic Disorder
Interventions
Neurofeedback, Sham feedback
Procedure
Lead sponsor
Yale University
Other
Eligibility
11 Years to 19 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Oct 29, 2026, 4:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Migraine in Adolescents

NCT05654012
View directory record Official record
Conditions
Migraine
Interventions
MRI, Thermal Stimuli, Pressure stimuli, Pain ratings, Pressure pain thresholds (PPT), Conditioned pain modulation (CPM) efficiency, Hormonal assessment, Migraine-related measures, Neural assessments, Pubertal status
Device · Behavioral · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
10 Years to 13 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Neurofeedback for Borderline Personality Disorder

NCT05398627
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Amygdala Neurofeedback
Device
Lead sponsor
Kymberly Young
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dyadic Neurofeedback for Development of Healthy Emotion Regulation in Youth

NCT05472545
View directory record Official record
Conditions
Emotional Regulation
Interventions
Neurofeedback
Behavioral
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
14 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional Results available

Treating Phobia With Multivoxel Neuro-reinforcement

NCT03655262
View directory record Official record
Conditions
Phobia
Interventions
Unconscious Neuro-reinforcement
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 29, 2026, 4:53 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

The Impact of Real-time Functional Magnetic Resonance Imaging (fMRI) Feedback on Response to Nicotine Cues

NCT01411007
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2016 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Real-Time Functional Magnetic Resonance Imaging Neurofeedback to Improve Motor Function in Cerebellar Ataxia

NCT05436249
View directory record Official record
Conditions
Healthy
Interventions
Neurofeedback treatment, At-home therapy
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Measuring the Impact of Real Time fMRI Neurofeedback in Borderline Personality Disorder

NCT04306341
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
real time fMRI neurofeedback
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Oct 29, 2026, 4:53 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in Depression

NCT05933148
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Siemens 7T MRI, Sham Neurofeedback
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Withdrawn Not applicable Interventional

Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD

NCT04543513
View directory record Official record
Conditions
PTSD, Cognitive Function
Interventions
Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
Other
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Real-Time fMRI Feedback Effects on Pain Perception

NCT01588197
View directory record Official record
Conditions
Cognitive Pain Control
Interventions
Attention/Distraction Strategy, Stimulus Quality/Severity Strategy, Control Strategy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 14, 2019 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain Network Modulation and Alcohol Use

NCT04828577
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Real Time Neurofeedback
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Recruiting Not applicable Interventional

Unconscious Reduction of Fear Through Decoded Neuro-Reinforcement

NCT06420557
View directory record Official record
Conditions
Phobia
Interventions
Unconscious Neuro-reinforcement
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 29, 2026, 4:53 PM EDT
Completed Not applicable Interventional

Comparing Real-time fMRI Neurofeedback Versus Sham for Altering Limbic and Eating Disturbances in Anorexia Nervosa

NCT04220112
View directory record Official record
Conditions
Anorexia, Anorexia Nervosa
Interventions
Real-Time Functional Magnetic Resonance Imaging (RT-fMRI), Sham Procedure
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Oct 29, 2026, 4:53 PM EDT