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ClinicalTrials.gov public records Last synced Oct 24, 2026, 8:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 409–432 of 909 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Reconstructive Surgery Clear all
Completed No phase listed Observational

Thumb Carpometacarpal Joint Denervation Versus Trapeziectomy

NCT03558204
View directory record Official record
Conditions
Thumb Osteoarthritis
Interventions
Denervation of the thumb CMC joint, trapeziectomy with ligament reconstruction (LRTI)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Timeline
2018 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 9, 2023 · Synced Oct 24, 2026, 8:54 AM EDT
Completed Not applicable Interventional

Low-Intensity Blood Flow Restriction Training as a Pre-Operative Rehabilitative Modality to Improve Post-Operative Outcomes for ACL Reconstruction

NCT04302558
View directory record Official record
Conditions
ACL Injury
Interventions
Exercise Blood Flow Restriction training, SHAM Exercise Blood Flow Restriction training
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years to 40 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 3, 2023 · Synced Oct 24, 2026, 8:54 AM EDT
Terminated Not applicable Interventional Results available

Moderated Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction

NCT02911909
View directory record Official record
Conditions
Anterior Cruciate Ligament Tear
Interventions
Delfi, Standard rehabilitation
Device · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 30 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Oct 24, 2026, 8:54 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction

NCT05161221
View directory record Official record
Conditions
Pain, Postoperative, ACL
Interventions
OxyCODONE 5 mg Oral Tablet, Naproxen 500 Mg, Tylenol Pill, Liposomal bupivacaine, Femoral Nerve Catheter
Drug · Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2021 · Synced Oct 24, 2026, 8:54 AM EDT
Completed Phase 1 Interventional

Twice Daily Enoxaparin Prophylaxis in Reconstructive Surgery Patients

NCT02687204
View directory record Official record
Conditions
Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus
Interventions
Twice daily enoxaparin prophylaxis, Real time dose adjustment
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 19, 2018 · Synced Oct 24, 2026, 8:54 AM EDT
Recruiting No phase listed Observational

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

NCT06883396
View directory record Official record
Conditions
Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder
Interventions
Medial Patellofemoral Ligament (MPFL) Reconstruction
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
10 Years to 35 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
16
States / cities
Redwood City, California • Gainesville, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 24, 2026, 8:54 AM EDT
Not yet recruiting Phase 1 Interventional

Restoration of Knee Extension After ACL Reconstruction

NCT07685561
View directory record Official record
Conditions
Knee, ACL
Interventions
Standard Physical Therapy, Ermi Knee Extensionater
Behavioral · Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
14 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 24, 2026, 8:54 AM EDT
Not listed No phase listed Observational

Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis: Patient Experiences and Reported Outcomes.

NCT06243718
View directory record Official record
Conditions
Diaphragmatic Paralysis, Pain, Chest, Breath Shortness
Interventions
Not listed
Lead sponsor
Advanced Reconstructive Surgery Alliance
Government
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Red Bank, New Jersey • Shrewsbury, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Oct 24, 2026, 8:54 AM EDT
Recruiting Not applicable Interventional

Tissue Reinforcement for Breast Reconstruction (TRBR) Pivotal Clinical Study (REDEFINE)

NCT06556654
View directory record Official record
Conditions
Breast Reconstruction Surgery
Interventions
TRBR Device
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
22 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
20
States / cities
Scottsdale, Arizona • Tucson, Arizona • Irvine, California + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Oct 24, 2026, 8:54 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

NATRELLE® 410 X-Style and L-Style Breast Implants Continued Access Study

NCT01870869
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Implant Revision
Interventions
Anatomically shaped, silicone-filled breast implants with low height/projection or extra-full projection
Device
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,951 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
58
States / cities
Beverly Hills, California • Campbell, California • Long Beach, California + 45 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2020 · Synced Oct 24, 2026, 8:54 AM EDT
Completed Not applicable Interventional

Abdominal Scar Improvement in Microsurgical Breast Reconstruction

NCT05377723
View directory record Official record
Conditions
Cicatrix, Breast Reconstruction
Interventions
Neodyne Device
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 24, 2026, 8:54 AM EDT
Not listed Phase 2 Interventional

Vascularized Composite Allotransplantation of the Hand

NCT00711373
View directory record Official record
Conditions
Upper Extremity Injuries
Interventions
Allogeneic hand transplantation
Procedure
Lead sponsor
Christina L. Kaufman PhD
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Oct 24, 2026, 8:54 AM EDT
Recruiting Early Phase 1 Interventional

MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)

NCT04572256
View directory record Official record
Conditions
ACL Injury, Meniscus Tear, Post-traumatic Osteoarthritis
Interventions
Montelukast, Placebo
Drug
Lead sponsor
Austin V Stone
Other
Eligibility
25 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 24, 2026, 8:54 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Botulinum Toxin A (Botox) in Tissue Expander Breast Reconstruction

NCT01591746
View directory record Official record
Conditions
Breast Cancer, Pain, Postoperative, BRCA1 Mutation, BRCA2 Mutation, Breast Diseases, Neoplasms
Interventions
Botulinum Toxin Type A, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Oct 24, 2026, 8:54 AM EDT
Completed No phase listed Observational

Computer Modeling With Reconstruction of Maxillofacial Skeleton

NCT00583856
View directory record Official record
Conditions
Maxillofacial Injury
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
11 Years to 50 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 20, 2010 · Synced Oct 24, 2026, 8:54 AM EDT
Not listed Not applicable Interventional

Hand Ligament Reconstructions With Knee Collateral Ligament Allografts

NCT05060900
View directory record Official record
Conditions
Hand Injuries, Wrist Injuries, Ligament Injury, Ligament Rupture, Ligament Avulsion
Interventions
Ligament Reconstruction with Allograft Ligament
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 24, 2026, 8:54 AM EDT
Active, not recruiting Not applicable Interventional

A Study of Near-Infrared Fluorescence Imaging With ICG During Reconstructive Gynecologic Surgery

NCT05071976
View directory record Official record
Conditions
Gynecologic Surgery
Interventions
ICG-NIR angiography
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 24, 2026, 8:54 AM EDT
Terminated Not applicable Interventional Results available

Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device

NCT02532517
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
CODMAN ENTERPRISE® Vascular Reconstruction Device and Delivery System
Device
Lead sponsor
Cerenovus, Part of DePuy Synthes Products, Inc.
Industry
Eligibility
21 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
11
States / cities
Englewood, Colorado • Gainesville, Florida • Jacksonville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2020 · Synced Oct 24, 2026, 8:54 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Regional Anesthesia Block in Fibula Free Flap Reconstruction

NCT03906838
View directory record Official record
Conditions
Anesthesia, Local, Surgery, Opioid Use, Pain, Postoperative, Head and Neck Neoplasms
Interventions
Ropivacaine injection
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 24, 2026, 8:54 AM EDT
Active, not recruiting Not applicable Interventional

An Investigational Surgical Procedure (Vascularized Lymph Node Transfer) in Reducing the Risk of Lymphedema in Patients With Breast Cancer Undergoing Breast Reconstruction

NCT03990610
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Mammoplasty, Vascularized Lymph Node Transfer
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 24, 2026, 8:54 AM EDT
Completed Phase 2 Interventional Results available

Study of GBT009 for Treatment of Incisional Wounds Following Breast Reconstruction Surgery

NCT01053897
View directory record Official record
Conditions
Scar Formation
Interventions
GBT009, Placebo
Biological
Lead sponsor
Garnet BioTherapeutics, Inc.
Industry
Eligibility
18 Years to 70 Years · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Chicago, Illinois • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2013 · Synced Oct 24, 2026, 8:54 AM EDT
Not listed Not applicable Interventional

Dermacell ADM Without Basement Membrane

NCT03667560
View directory record Official record
Conditions
Breast Cancer
Interventions
Dermacell ADM without basement membrane, FlexHD
Procedure
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Oct 24, 2026, 8:54 AM EDT
Active, not recruiting Not applicable Interventional

Anterior Cruciate Ligament Reconstruction Hybrid Remnant Repair

NCT05494073
View directory record Official record
Conditions
Anterior Cruciate Ligament Tear
Interventions
ACL Reconstruction with Hybrid Remnant Repair, ACL Reconstruction without Hybrid Remnant Repair
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
13 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 8, 2025 · Synced Oct 24, 2026, 8:54 AM EDT
Withdrawn No phase listed Observational

Clinical Safety and Efficacy of Infrared Neural Stimulation During Nerve Transfers

NCT04601337
View directory record Official record
Conditions
Infrared Neural Stimulation (INS)
Interventions
Infrared Neural Stimulation
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Oct 24, 2026, 8:54 AM EDT