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ClinicalTrials.gov public records Last synced Oct 25, 2026, 2:58 PM EDT

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Showing 553–576 of 909 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Reconstructive Surgery Clear all
Completed Not applicable Interventional

Immediate Vaginal Reconstruction After Oncologic Resection: Surgical Outcomes, Patient Satisfaction and Sexual Function

NCT00588081
View directory record Official record
Conditions
Vaginal Cancer
Interventions
QOL
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Natrelle(TM) Cohesive Round Silicone-Filled Breast Implants

NCT00689871
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Revision of Augmentation or Reconstruction
Interventions
Natrelle(TM) Silicone-Filled Breast Implants
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
715 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 13, 2014 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Not applicable Interventional

Evaluation of a 3-D Tomosynthesis Mammography System Used in Conjunction With Conventional 2-D Digital Mammography

NCT00754598
View directory record Official record
Conditions
Breast Cancer
Interventions
Tomosynthesis digital mammography imaging system
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
5
States / cities
New Haven, Connecticut • Iowa City, Iowa • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2022 · Synced Oct 25, 2026, 2:58 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments

NCT03288207
View directory record Official record
Conditions
Obesity
Interventions
AMRA(r) Researcher Image reconstruction software, MRI: radiofrequency coils (Device Manufacturer: Siemens Medical Solutions USA, Inc.), MRI: Research pulse sequences (Device Manufacturer: NIH), MRI: Image Reconstruction and Analysis Software (Device Manufacturer: NIH), Bluetooth-enabled glucometer, Remote tailored-to-place coaching (TPC), Standard remote coaching (SRC), Run-in physical-activity monitoring, Ambulatory blood-pressure monitor, Polysomnography equipment
Device · Other
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years to 75 Years · Female only
Enrollment
325 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 25, 2026, 2:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessing the Results of Lip Surgery in Patients With Cleft Lip and Palate

NCT00070811
View directory record Official record
Conditions
Cleft Lip, Cleft Lip and Palate
Interventions
Lip revision surgery
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
3 Months to 21 Years
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 4, 2013 · Synced Oct 25, 2026, 2:58 PM EDT
Recruiting Not applicable Interventional

A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products

NCT06979804
View directory record Official record
Conditions
ACL Reconstruction, Meniscus Tears, Anterior Cruciate Ligament Rupture
Interventions
Semiconducting fabric sleeves, Non-semiconducting fabric sleeves
Device
Lead sponsor
Illinois Center for Orthopaedic Research and Education
Other
Eligibility
16 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Westmont, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Half-Dose Molecular Breast Imaging With Wide Beam Reconstruction Processing

NCT01653964
View directory record Official record
Conditions
Breast Cancer
Interventions
Molecular breast imaging
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years and older · Female only
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Oct 25, 2026, 2:58 PM EDT
Completed No phase listed Observational

High Image Matrix CT Reconstruction

NCT02610465
View directory record Official record
Conditions
Healthy Subjects, Pulmonary-Related Conditions, Cardiac-Related Conditions
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 99 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 25, 2026, 2:58 PM EDT
Recruiting Phase 2 Interventional

Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery

NCT07020312
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Hip Arthroscopy
Interventions
Visualization training with neurofeedback, Standard post-surgical rehabilitation therapy
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Phase 4 Interventional

The Role of Antibiotics in Full Thickness Skin Graft Survival for Facial Reconstructive Surgery

NCT01912651
View directory record Official record
Conditions
Facial Defect
Interventions
cephalexin
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 25, 2026, 2:58 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure

NCT06575166
View directory record Official record
Conditions
Ventral Hernia, Incisional Hernia, Parastomal Hernia
Interventions
Abdominal wall tension, Intra-abdominal pressure
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Not applicable Interventional Results available

Werewolf Flow 50 During ACL Reconstruction

NCT04998656
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Arthrofibrosis of Knee
Interventions
Werewolf FLOW 50, Control
Device · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 18 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Aurora, Colorado • Broomfield, Colorado • Highlands Ranch, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Not applicable Interventional Results available

Sientra Sponsored Silimed Gel-Filled Breast Implant Core Clinical Study

NCT00905645
View directory record Official record
Conditions
Breast Augmentation, Breast Reconstruction, Breast Revision
Interventions
Silimed Gel-Filled Mammary Implant
Device
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
18 Years and older · Female only
Enrollment
1,788 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2018
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2024 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Phase 4 Interventional Results available

Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction

NCT03704376
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury
Interventions
30 ml of 0.2% ropivacaine, 15 ml of 0.2% ropivacaine, 100 mcg clonidine, High-frequency linear ultrasound transducer
Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
16 Years to 30 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Oct 25, 2026, 2:58 PM EDT
Recruiting Not applicable Interventional

Melodi Matrix™ in Breast Reconstruction

NCT06027996
View directory record Official record
Conditions
Breast Reconstruction
Interventions
Absorbable Antibacterial Matrix
Device
Lead sponsor
Melodi Health, Inc.
Industry
Eligibility
22 Years and older · Female only
Enrollment
702 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
10
States / cities
Palo Alto, California • Ann Arbor, Michigan • Rochester, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Not applicable Interventional Results available

Tissue Expander Breast Reconstruction Study on Breast Volume and Shape Change

NCT01222390
View directory record Official record
Conditions
Contour Irregularity of Reconstructed Breast
Interventions
Contour Profile Tissue Expander
Device
Lead sponsor
Northwestern University
Other
Eligibility
25 Years to 85 Years · Female only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 25, 2026, 2:58 PM EDT
Terminated Phase 4 Interventional Results available

Impact of Topical Tranexamic Acid in Breast Reconstruction

NCT05807074
View directory record Official record
Conditions
Breast Cancer
Interventions
Tranexamic Acid, Saline
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of HMB Supplementation on Recovery Following ACL Surgery

NCT02602561
View directory record Official record
Conditions
ACL Injury
Interventions
HMB, Placebo
Dietary Supplement
Lead sponsor
Metabolic Technologies Inc.
Industry
Eligibility
18 Years to 49 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Oct 25, 2026, 2:58 PM EDT
Active, not recruiting Not applicable Interventional

Patient-Specific Decision Aid System for Shared Decision Making About Breast Reconstruction

NCT05130580
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Enhanced Consultation, Standard of Care Consultation, Conventional Imaging, Educational Intervention, Questionnaire Administration
Other · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
21 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 25, 2026, 2:58 PM EDT
Recruiting Not applicable Interventional

Shockwave in Postoperative Breast Reconstruction Fibrosis

NCT06919042
View directory record Official record
Conditions
Fibrosis Breast
Interventions
Pulsed Acoustic Cellular Expression therapy
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 25, 2026, 2:58 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Pectoralis (II) Block With Liposomal Bupivacaine vs Bupivacaine for Breast Surgery

NCT03383198
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Liposomal bupivacaine right injection, Liposomal bupivacaine left injection
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Not applicable Interventional Results available

Structural Fat Grafting for Craniofacial Trauma Using Manual Technique for Processing Fat Graft Material

NCT02267187
View directory record Official record
Conditions
Facial Injuries
Interventions
Fat Grafting, General Anesthesia, Coleman Cannulas, Tefla non-adherent gauze pad
Procedure · Drug · Device + 1 more
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 24, 2018 · Synced Oct 25, 2026, 2:58 PM EDT
Completed Phase 4 Interventional Results available

Acellular Dermal Matrix in Tissue Expander Breast Reconstruction: A Prospective, Randomized, Clinical Trial Comparing SurgiMend PRS and AlloDerm RTU

NCT01781299
View directory record Official record
Conditions
Breast Cancer, Mastectomy
Interventions
AlloDerm RTU, SurgiMend PRS
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 12, 2017 · Synced Oct 25, 2026, 2:58 PM EDT
Active, not recruiting Not applicable Interventional

Comparing Perioperative Education Modalities for ACL Reconstruction on Patient Satisfaction, Self-Efficacy, and Surgical Outcomes

NCT05273463
View directory record Official record
Conditions
ACL Injury, Anterior Cruciate Ligament Injuries
Interventions
Video-Based Intervention, Classroom-Based Intervention
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
15 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 25, 2026, 2:58 PM EDT