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ClinicalTrials.gov public records Last synced Nov 1, 2026, 6:21 PM EST

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Showing 1537–1560 of 2,209 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Reduced Activity Clear all
Recruiting Phase 4 Interventional

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)

NCT07145866
View directory record Official record
Conditions
Nicotine Dependence, Transcranial Magnetic Stimulation, Vaping, Smoking Cessation, Smoking (Tobacco) Addiction
Interventions
Varenicline, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham, Nicotine Cessation Counseling, D-cycloserine
Drug · Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Nov 1, 2026, 6:21 PM EST
Completed Not applicable Interventional

Pain Management Following Musculoskeletal Injury

NCT01689675
View directory record Official record
Conditions
Musculoskeletal Strain, Musculoskeletal Sprain, Injury of Musculoskeletal System
Interventions
Computer based pain management
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Baltimore, Maryland • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Nov 1, 2026, 6:21 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of an Entrepreneurship Program for American-Indian Youth

NCT02157493
View directory record Official record
Conditions
Depressive Symptoms, Substance Use
Interventions
Arrowhead Business Group Curriculum, Recreational League Control Condition
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
13 Years to 15 Years
Enrollment
449 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Nov 1, 2026, 6:21 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Parents and Children Together Preventing Diabetes (PACT PD)

NCT01819493
View directory record Official record
Conditions
Diabetes Prevention
Interventions
Lifestyle Intervention, Standard Family-Based intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
8 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Nov 1, 2026, 6:21 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Transcranial Direct Current Stimulation Intensity on Leg Muscle Fatigability in Healthy Adults

NCT04321304
View directory record Official record
Conditions
Healthy
Interventions
Sham transcranial direct current stimulation, Transcranial direct current stimulation at 2 mA, Transcranial direct current stimulation at 4 mA
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 30 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Nov 1, 2026, 6:21 PM EST
Terminated Not applicable Interventional Results available

Celliant Socks to Increase Tissue Oxygenation and Complete Wound Closure in Diabetic Foot Wounds

NCT04709419
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Celliant Diabetic Medical Socks, Control (placebo) Medical Socks
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
22 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2025 · Synced Nov 1, 2026, 6:21 PM EST
Completed Not applicable Interventional Results available

An Evaluation of MBSR and CBT for Veterans With Chronic Pain

NCT04486066
View directory record Official record
Conditions
Chronic Pain, Pain
Interventions
Mindfulness-Based Stress Reduction, Cognitive Behavioral Therapy for Chronic Pain, Usual Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Nov 1, 2026, 6:21 PM EST
Completed Not applicable Interventional

Precision-Based Approach to Matching Evidence-Based Interventions to Students With Externalizing Behaviors

NCT05752942
View directory record Official record
Conditions
Problem;Behaviour;Child
Interventions
Student Intervention Matching System (SIMS), group-based social skills training
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
9 Years to 12 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 3, 2023 · Synced Nov 1, 2026, 6:21 PM EST
Enrolling by invitation Not applicable Interventional

Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic Trauma

NCT06069154
View directory record Official record
Conditions
Rib Fracture, Rib Fracture Multiple
Interventions
Cryoneurolysis, Local anesthetic peripheral nerve block, Sham Cryoneurolysis, Sham peripheral nerve block
Device · Procedure
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
5
States / cities
La Jolla, California • Bethesda, Maryland • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Nov 1, 2026, 6:21 PM EST
Completed Phase 3 Interventional

Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin Syndrome

NCT06050122
View directory record Official record
Conditions
Gorlin Syndrome
Interventions
Patidegib Topical Gel, Patidegib Topical Gel with no active patidegib
Drug
Lead sponsor
Sol-Gel Technologies, Ltd.
Industry
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
24
States / cities
Rogers, Arkansas • Fremont, California • Los Angeles, California + 21 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Nov 1, 2026, 6:21 PM EST
Recruiting Phase 1 Interventional

IS-free Treg HaploHCT

NCT04678401
View directory record Official record
Conditions
Stem Cell Transplant Complications, Graft Vs Host Disease, Myeloid Leukemia, Acute, Myeloid Leukemia in Relapse (Disorder), Myelodysplastic Syndromes
Interventions
Radiation, Fludarabine, Thiotepa, Cyclophosphamide, Mesna, Treg-enriched donor cell, Unmodified donor T Cell, CD34+ Haplo Peripheral Blood Stem Cell, Melphalan
Radiation · Drug · Biological + 1 more
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Nov 1, 2026, 6:21 PM EST
Recruiting Not applicable Interventional

Low Voltage Electrical Stimulation for Depression in Parkinson's Patients

NCT06467695
View directory record Official record
Conditions
Parkinson Disease, Depressive Symptoms
Interventions
BIOPAC Stimsola, BIOPAC Stimsola Sham (zero amps)
Device
Lead sponsor
University of South Alabama
Other
Eligibility
19 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Nov 1, 2026, 6:21 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy

NCT07122739
View directory record Official record
Conditions
Healthy
Interventions
Active Real-time fMRI Neurofeedback, Sham Real-time fMRI neurofeedback
Behavioral
Lead sponsor
Trustees of Princeton University
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Nov 1, 2026, 6:21 PM EST
Recruiting Not applicable Interventional

ESP Block in MIS Lumbar Spine Surgery

NCT05856539
View directory record Official record
Conditions
Patients With Spinal Stenosis Indicated for MIS TLIF
Interventions
Erector spinae plane (ESP) block
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Nov 1, 2026, 6:21 PM EST
Completed Phase 1 Interventional

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

NCT04374877
View directory record Official record
Conditions
Advanced Solid Tumor, Clear Cell Renal Cell Carcinoma, Hepatocellular Carcinoma, Non-small Cell Lung Cancer
Interventions
CHS-388, Pembrolizumab, Toripalimab
Drug
Lead sponsor
Coherus Oncology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
18
States / cities
Duarte, California • Los Angeles, California • San Francisco, California + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Nov 1, 2026, 6:21 PM EST
Recruiting Phase 2 Interventional

Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal Therapy

NCT07215273
View directory record Official record
Conditions
Invasive Mould Infection
Interventions
EL219, Active Comparator- IV Antifungal (LAmB or voriconazole)
Drug
Lead sponsor
Elion Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
11
States / cities
Birmingham, Alabama • Sacramento, California • Augusta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Nov 1, 2026, 6:21 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Burnout Reduction and Engagement App-based Trial of Headspace (BREATHE)

NCT05036356
View directory record Official record
Conditions
Burnout, Professional
Interventions
Headspace App
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 9, 2022 · Synced Nov 1, 2026, 6:21 PM EST
Completed Phase 2 Interventional

A Pilot Trial to Determine the Efficacy of Lactobacillus Rhamnosus for Reducing Colonization by Methicillin-resistant Staphylococcus Aureus (MRSA) (PROSE)

NCT01112995
View directory record Official record
Conditions
Infection
Interventions
Lactobacillus rhamnosus, Sugar pill (placebo)
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Nov 1, 2026, 6:21 PM EST
Terminated Not applicable Interventional Results available

Accelerated rTMS for the Reduction of Nicotine Craving

NCT03352609
View directory record Official record
Conditions
Nicotine Use Disorder, Nicotine Dependence
Interventions
Active rTMS with MagVenture MagPro double blind rTMS system, Sham rTMS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Nov 1, 2026, 6:21 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

HIV Prevention Among Latino MSM: Evaluation of a Locally Developed Intervention

NCT01626898
View directory record Official record
Conditions
Risk Reduction Behavior
Interventions
HOLA en Grupos, General Health intervention (comparison intervention )
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Male only
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2016 · Synced Nov 1, 2026, 6:21 PM EST
Active, not recruiting Not applicable Interventional

Pilot MBSR for People With HS

NCT07903948
View directory record Official record
Conditions
Hidradenitis Suppurativa (HS)
Interventions
Mindfulness-Based Stress Reduction
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 29, 2026 · Synced Nov 1, 2026, 6:21 PM EST
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Study to Assess the Effectiveness of a Heat Risk Reduction Decision Support Platform and the Barriers and Facilitators of Its Implementation With 30 US Local Health Department Sites

NCT06971978
View directory record Official record
Conditions
Extreme Heat, Heat Health, Extreme Heat Waves, Heat, Emergency Preparedness, Disaster Management, Disaster Planning, Disasters
Interventions
Online decision support platform to support evidence-based heat health risk assessment and extreme heat event preparedness planning, Heat and health risk assessment and preparedness information
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Nov 1, 2026, 6:21 PM EST
Recruiting Phase 2 Interventional

The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking

NCT04084860
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
CI-581a, CI-581b, MBRP, MET
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Nov 1, 2026, 6:21 PM EST
Active, not recruiting Phase 4 Interventional

L-arginine to Reduce Sympathetic Nerve Activity in CKD Patients

NCT03982160
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
L-Arginine, Placebo
Drug · Other
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
35 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
2
States / cities
Newark, Delaware • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Nov 1, 2026, 6:21 PM EST