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ClinicalTrials.gov public records Last synced Nov 10, 2026, 9:04 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2089–2112 of 2,213 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Reduced Activity Clear all

Conditions: Nicotine Use Disorder, Substance Use Disorders
Interventions: Active TI-NDBS, Sham TI-NDBS, tDCS; Device · Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Bloomington, Indiana

Conditions: Obesity
Interventions: Small changes weight loss program; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cardiovascular Diseases, Atherosclerosis, Postmenopause, Heart Diseases
Interventions: Diet, fat-restricted, Exercise; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 52 Years to 60 Years · Female only
Enrollment: 508 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2010
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Impulsivity, Compulsive Overeating, Obesity
Interventions: Device: Active Transcranial Direct Current Stimulation (tDCS) coupled with cognitive training, Device: Sham Transcranial Direct Current Stimulation (tDCS) coupled with cognitive training; Device
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Burnout Syndrome, Surgery, Stress
Interventions: Mindfulness Based Stress Reduction - modified, Active listening and reading; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Anger, Aggression
Interventions: ACT with RAGE-Control; Behavioral
Lead sponsor: Gonzalez-Heydrich, Joseph, M.D.; Individual
Eligibility: 8 Years to 17 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Alzheimer Disease, Physical Activity
Interventions: Beat-accentuated, personalized music stimulation (BMS), Strength Training (ST), Aerobic exercise (AE); Behavioral
Lead sponsor: Emory University; Other
Eligibility: 65 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Atlanta, Georgia • Greensboro, North Carolina

Conditions: Breast Cancer, Obesity, Weight Changes
Interventions: behavioral dietary intervention, exercise intervention, telephone-based intervention, counseling intervention, educational intervention, immunoenzyme technique, laboratory biomarker analysis, questionnaire administration, study of socioeconomic and demographic variables, evaluation of cancer risk factors, support group therapy; Behavioral · Other · Procedure
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 30 Years to 50 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2004
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cannabis Use Disorder
Interventions: Approach Bias Modification (ABM), Sham ABM, Psychosocial therapy for cannabis use disorder.; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Crohn's Disease
Interventions: Vedolizumab, Upadacitinib, Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 396 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 19
States / cities: La Jolla, California • Los Angeles, California • Colorado Springs, Colorado + 12 more

Conditions: Smoking Cessation
Interventions: Internet-All Nations Breath of Life (I-ANBL), Honoring the Gift of Heart Health, Nicotine gum, Patch, or Lozenge or Zyban® or Chantix®; Other · Drug
Lead sponsor: Won Choi, PhD, MPH; Other
Eligibility: 18 Years and older
Enrollment: 251 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 2
States / cities: Kansas City, Kansas • Pablo, Montana

Conditions: Overweight, Obesity
Interventions: Online Weight Management Program with Coaching and Patient Navigator Support; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 20 Years and older
Enrollment: 5,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: PTSD, Post Traumatic Stress Disorder
Interventions: OTX-601 Digital Therapeutic, OTX-003 Comparator app; Device
Lead sponsor: Oui Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Schizophrenia
Interventions: Brexpiprazole (OPC-34712), Aripiprazole, Placebo; Drug
Lead sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.; Industry
Eligibility: 13 Years to 17 Years
Enrollment: 316 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Sedentary Behaviors, Screen Time, Physical Activity, Glucose Metabolism, Sleep Quality, HbA1c Level
Interventions: Non-Sedentary Behavior Habit Formation, Sedentary Screen Time Reduction Smartphone App; Behavioral
Lead sponsor: Arizona State University; Other
Eligibility: 23 Years to 64 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Tempe, Arizona • San Luis Obispo, California

Conditions: Breast Cancer
Interventions: Reduced Sedentary Time Intervention (RSTI); Behavioral
Lead sponsor: Baystate Medical Center; Other
Eligibility: 20 Years to 80 Years · Female only
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Obesity, Overweight and Obesity, Overweight
Interventions: Tirzepatide; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Smoking, Smoking Cessation, Motivation, Nicotine Dependence
Interventions: Nicotine Patch, Nicotine Gum, Motivational Interviewing, Smoking Reduction, No Intervention, Nicotine Patch + Nicotine Gum; Drug · Behavioral · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 99 Years
Enrollment: 517 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Metabolic Disorders, Physical Inactivity, Vascular Disease Risk
Interventions: reduced physical activity; Other
Lead sponsor: Miami University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Oxford, Ohio

Conditions: Type 2 Diabetes
Interventions: Dietary, Physical Activity, Self-Regulatory Approaches; Behavioral
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 21 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: HIV
Interventions: Disclosure Intervention, Attention Control Case Management; Behavioral
Lead sponsor: University of South Florida; Other
Eligibility: 18 Years and older · Male only
Enrollment: 340 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: HIV-1-infection, ART, Cd4+ Lymphocyte Deficiency, Lymphoid Tissue; Infection, Interleukin
Interventions: FT538, Vorinostat; Biological · Drug
Lead sponsor: Masonic Cancer Center, University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Autosomal Dominant Polycystic Kidney, Overweight and Obesity
Interventions: Daily caloric restriction, Standard advice control; Behavioral · Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 65 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Cerebrovascular Accident
Interventions: Hand Mentor; Device
Lead sponsor: Kinetic Muscles; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 2
States / cities: Phoenix, Arizona • Atlanta, Georgia

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Temporal Interference Neurostimulation and Addiction

A Small Changes Weight Loss Program and Message Dissemination Via Facebook in Chicago's West Side

Reduction of Triglycerides in Women on Hormone Replacement Therapy

tDCS for Impulsivity and Compulsivity in Obesity

Mindful Mental Training for Surgeons to Enhance Resilience and Performance Under Stress

Reducing Aggression in Children and Adolescent on an Inpatient Unit

Inspiring Seniors Towards Exercise Promotion to Protect Cognition

A Weight-Loss Program in Helping Obese Black Women Lose Weight

Approach Bias Modification for the Treatment of Cannabis Use Disorder

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

Web-based Smoking Cessation Program for Tribal College Students

Partnerships for Reducing Overweight and Obesity with Patient-Centered Strategies 2.0

Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms

Trial to Evaluate the Short-term Safety & Efficacy of Brexpiprazole Monotherapy in the Treatment of Adolescents With Schizophrenia

StandUPTV Habits: Feasibility Trial for Maintaining Reductions in Sedentary Screen Time

A Home-Based Study to Enhance Activity in Breast Cancer Survivors

Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity

Identifying Treatments to Motivate Smokers to Quit

Interactive Roles of Cardiorespiratory Fitness and Adiposity on Glucose and Vascular Control After Physical Inactivity

Development of Self-Regulation in Individuals With Type 2 Diabetes

Intervention to Assist MSM Disclose HIV Status to Casual Sex Partners

Ph1 Study of FT538 Alone and With Vorinostat for Persistent Low-Level HIV Viremia

Daily Caloric Restriction in ADPKD

Study of Hand Therapy 3 to 24 Months After Stroke