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Showing 1–24 of 141 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Reduced carbohydrate diet Clear all
Recruiting Not applicable Interventional

Living Well With Lymphoma

NCT06047626
View directory record Official record
Conditions
Lymphoma
Interventions
Fatigue Reduction Diet, General Health Curriculum
Other
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Liking Adaptation to Beverages With Varying Sweetness Levels After Prolonged Exposure

NCT04609657
View directory record Official record
Conditions
Sweetness Liking Adaptation
Interventions
Flavored carbonated soft drink (CSD)
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
25 Years to 55 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 23, 2022 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders

NCT06554873
View directory record Official record
Conditions
Smoking Cessation, Harm Reduction
Interventions
Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product, NJOY e-cigarette, on!
Drug · Other
Lead sponsor
Rose Research Center, LLC
Industry
Eligibility
22 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Charlotte, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Not applicable Interventional

Extension Family Lifestyle Intervention Project (E-FLIP for Kids)

NCT01820338
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Child Tx Contacts, Behavioral Parent-Tx Contacts, Dietary and Physical Activity Information
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
8 Years to 12 Years
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 19, 2015 · Synced Sep 11, 2026, 8:17 PM EDT
Active, not recruiting Not applicable Interventional

Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia

NCT06998238
View directory record Official record
Conditions
Overweight and Obesity, Hyperandrogenemia, Insulin Resistance
Interventions
Mediterranean-based, carbohydrate restricted, calorie reduced diet
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Validation of Biomarkers of Exposure and Host Response

NCT00468234
View directory record Official record
Conditions
Cigarette Smoker
Interventions
nicotine polacrilex, nicotine transdermal system, nicotine inhaler
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Sep 11, 2026, 8:17 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health

NCT02706262
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Metabolically abnormal obese - Mediterranean diet, Metabolically abnormal obese - Low carbohydrate ketogenic diet, Metabolically abnormal obese - Plant-based, very-low-fat diet, Annual Follow-up Visits
Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 11, 2026, 8:17 PM EDT
Recruiting Not applicable Interventional

Efficacy of Viome's Precision Nutrition Program Towards Reducing HbA1c

NCT05465616
View directory record Official record
Conditions
Diabetes, Pre Diabetes
Interventions
Viome's Precision Nutrition Program (VPNP)
Dietary Supplement
Lead sponsor
Viome
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Bothell, Washington
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Nutritional Counseling Tool in Reducing the Amount and Frequency of Sugar Intake

NCT06673342
View directory record Official record
Conditions
Dental Cavity, Caries,Dental
Interventions
Nutritional Counseling
Behavioral
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Sep 11, 2026, 8:17 PM EDT
Recruiting Not applicable Interventional

Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes

NCT05899166
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Ketogenic diet, food delivery and education, Standard diet, food delivery and education
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
5 Years to 12 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Role of Carbohydrate Modification in Weight Management Among Obese Children

NCT00215111
View directory record Official record
Conditions
Childhood Obesity
Interventions
Low carbohydrate, reduced glycemic load, and a control diet
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 12 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2015 · Synced Sep 11, 2026, 8:17 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Think AHEAD (A Healthy Eating And Drinking) Study

NCT01044134
View directory record Official record
Conditions
Obesity
Interventions
Dietary counseling
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2015 · Synced Sep 11, 2026, 8:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Groceries for Residents of Southeastern USA to Stop Hypertension

NCT06891911
View directory record Official record
Conditions
Hypertension, Elevated Blood Pressure, Cardiovascular Diseases, Dietary Intervention
Interventions
Dietitian-Assisted DASH groceries, Self-directed shopping
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Pain in Amputees Reduced by Administration of Diet Examination

NCT05460845
View directory record Official record
Conditions
Amputation, Phantom Limb Pain, Residual Limb Pain
Interventions
Low-Carbohydrate Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Sep 11, 2026, 8:17 PM EDT
Active, not recruiting Not applicable Interventional

Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD

NCT04861571
View directory record Official record
Conditions
NAFLD
Interventions
Dietary intervention with very low calorie diet (VLCD), Control Arm
Dietary Supplement · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1

NCT00158171
View directory record Official record
Conditions
Smoking Cessation, Tobacco Use Disorder
Interventions
Nicotine Replacement Therapies, Nicotine patch, Folic Acid
Drug · Dietary Supplement
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
13 Years to 18 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Sep 11, 2026, 8:17 PM EDT
Recruiting Phase 2 Interventional

SMART Diets for MASLD

NCT07459504
View directory record Official record
Conditions
Metabolic-dysfunction Associated Steatotic Liver Disease
Interventions
Essential Amino Acids Supplementation intervention, Low sugar diet
Drug · Other
Lead sponsor
Michigan State University
Other
Eligibility
11 Years to 17 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 11, 2026, 8:17 PM EDT
Not yet recruiting Phase 4 Interventional

Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment

NCT07809854
View directory record Official record
Conditions
Cigarette Smoking, Veterans
Interventions
Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling, Healthy Changes Counseling
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a High-Protein Diet and/or High-Intensity Training on Metabolic Syndrome

NCT01622634
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Sprint Interval Exercise, Higher PRO Diet, Higher CARB Diet
Behavioral · Other
Lead sponsor
University of Georgia
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Sep 11, 2026, 8:17 PM EDT
Recruiting Phase 4 Interventional

Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

NCT07058155
View directory record Official record
Conditions
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
Interventions
Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), Lifestyle Counseling - Diet & Physical-Activity Program
Procedure · Drug · Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Phase 4 Interventional

Effects of Saxagliptin on Adipose Tissue Inflammation in Humans

NCT02285985
View directory record Official record
Conditions
Type 2 Diabetes Mellitus (T2DM)
Interventions
Saxagliptin, Placebo
Drug
Lead sponsor
Phoenix VA Health Care System
Federal
Eligibility
21 Years to 70 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 21, 2024 · Synced Sep 11, 2026, 8:17 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Low-CArbohydrate Diet and SGLT2-INhibitOr to Achieve Moderate Ketosis in Healthy Volunteers

NCT05662865
View directory record Official record
Conditions
Ketones, Metabolism
Interventions
SGLT2 inhibitor, Controlled, Adaptive Study Diet
Drug · Other
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 11, 2026, 8:17 PM EDT
Terminated Not applicable Interventional

Mediterranean Diet and Protein-Sparing Modified Diet for Metabolic Syndrome in Liver Transplant Recipients

NCT02174783
View directory record Official record
Conditions
Liver Transplantation, Metabolic Syndrome X, Obesity
Interventions
Control group, Mediterranean diet, Protein-Sparing Modified Fast (PSMF)
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Sep 11, 2026, 8:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Reduced Carbohydrate Diet Intervention for Polycystic Ovary Syndrome (PCOS)

NCT01028989
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
Reduced Glycemic Load Diet, Standard Diet
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 50 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Sep 11, 2026, 8:17 PM EDT