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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Referral to PTSD Treatment Clear all
Recruiting Not applicable Interventional

Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery

NCT07115030
View directory record Official record
Conditions
Opioid Use Disorder, Intimate Partner Violence (IPV), Post Traumatic Stress Disorder PTSD
Interventions
PCT+2HOPE
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
532 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Bridgeport, Connecticut • Enfield, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Behavioral Health for Caregivers and Children After Pediatric Injury

NCT06856057
View directory record Official record
Conditions
Quality of Life, PTSD, Depression Not Otherwise Specified, Child Externalizing Behavior
Interventions
Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
348 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
4
States / cities
Los Angeles, California • Lexington, Kentucky • Ann Arbor, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional

Testing the Effectiveness of a Therapist-Assisted Self-Management Program for Veterans Who Finished PTSD Therapy

NCT05797441
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder
Interventions
EMPOWER, Treatment As Usual
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
8
States / cities
Sepulveda, California • Tampa, Florida • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Recruiting Not applicable Interventional

Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers

NCT05751473
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Prolonged Exposure for Primary Care (PE-PC), EAP Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
14
States / cities
San Diego, California • Carrollton, Georgia • Ann Arbor, Michigan + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Recruiting Not applicable Interventional

Testing a Scalable Model of Care to Improve Patients Access to Mental Health Services After Traumatic Injury

NCT05497115
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression
Interventions
Trauma Resilience and Recovery Program
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Washington, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Enrolling by invitation Not applicable Interventional

Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails

NCT07490717
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder, Stimulant Use & Co-occuring Opioid Use Disorders, Co-occurring Mental and Substance Use Disorders, Medications for Opioid Use Disorder
Interventions
Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional Results available

Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans

NCT02657317
View directory record Official record
Conditions
Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder, Depression, Opioid Use Disorder
Interventions
FORT-A, VA Treatment as Usual
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 72 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Sep 26, 2026, 2:26 AM EDT
Active, not recruiting Not applicable Interventional

Testing a PTSD m-Health Intervention to Improve Alcohol Treatment Outcomes

NCT05564663
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Alcohol Use Disorder
Interventions
PTSD Coach App + Brief Support, Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Enrolling by invitation Not applicable Interventional

Strength at Home - Parents RCT

NCT06309329
View directory record Official record
Conditions
Parent-Child Relations
Interventions
Strength at Home Parents, VA treatment as usual
Behavioral
Lead sponsor
VISN 17 Center of Excellence
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional Results available

An Evaluation of MBSR and CBT for Veterans With Chronic Pain

NCT04486066
View directory record Official record
Conditions
Chronic Pain, Pain
Interventions
Mindfulness-Based Stress Reduction, Cognitive Behavioral Therapy for Chronic Pain, Usual Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Sep 26, 2026, 2:26 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Adaptation of the PCIP for Spanish Speaking Adolescents and Families

NCT05899322
View directory record Official record
Conditions
Post-Traumatic Stress Disorder in Adolescence, Post Traumatic Stress Disorder
Interventions
Primary Care Intervention for PTSD Spanish Speaking Adolescents, Waitlist Treatment as Usual
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 22 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation and Treatment of Substance Abuse in Veterans With PTSD Disability Claims

NCT01597856
View directory record Official record
Conditions
Attendance at Treatment, PTSD, Substance Use, and Attendance at Treatment
Interventions
SBIRT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
346 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
West Haven, Connecticut • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional Results available

Primary Care Treatment Integrating Motivation and Exposure

NCT03812146
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Alcohol-Related Disorders
Interventions
PC-TIME, PC-TAU
Behavioral
Lead sponsor
Syracuse VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Buffalo, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Sep 26, 2026, 2:26 AM EDT
Active, not recruiting Not applicable Interventional

A Deployment Focused Pragmatic Trial of Optimal Stepped Care Intervention Targeting PTSD and Comorbidity for Acutely Hospitalized Injury Survivors Treated in US Trauma Care Systems

NCT05632770
View directory record Official record
Conditions
PTSD, Physical Injury
Interventions
Stepped Collaborative Care, American College of Surgeons (ACS) Required Screening and Referral (Usual Care)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Not yet recruiting Not applicable Interventional

The Healing and Empowerment Actions for Recovery From Trauma (HEART) Trial

NCT07584252
View directory record Official record
Conditions
Trauma Blunt, Orthopedic
Interventions
Comprehensive trauma recovery programming (C-TRP), Standard of Care (Investigator Selected)
Behavioral · Other
Lead sponsor
Stephanie Di Stasi
Other
Eligibility
18 Years and older
Enrollment
804 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
7
States / cities
Aurora, Colorado • Baltimore, Maryland • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional

Dialectical Behavior Therapy for Pregnant Women

NCT03938350
View directory record Official record
Conditions
Perinatal Depression
Interventions
Dialectical Behavior Therapy (DBT) Skills Training
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 29, 2022 · Synced Sep 26, 2026, 2:26 AM EDT
Recruiting Not applicable Interventional

Testing an Integrated PTSD and Weight Management Intervention: A Hybrid Type 1 Trial

NCT07010757
View directory record Official record
Conditions
PTSD, Obesity
Interventions
HARPP, control arm for HARPP trial
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Active, not recruiting Not applicable Interventional

Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault

NCT06444295
View directory record Official record
Conditions
Posttraumatic Stress Symptom, Alcohol Drinking, Alcohol Problem
Interventions
Activity scheduling, Cognitive restructuring, Coaching calls, Non-core intervention components
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
464 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional

Efficacy Trial of Stress Check-Up

NCT03423394
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Motivational Enhancement Therapy, Treatment as Usual
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional

Treatment of Post-Traumatic Stress Disorder (PTSD) and Chronic Pain After Traumatic Orthopedic Injury

NCT00957164
View directory record Official record
Conditions
Chronic Pain, Post-traumatic Stress Disorder
Interventions
Brief Prolonged Exposure Protocol, Chronic Pain Management Treatment, Self-Care
Behavioral
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 70 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
4
States / cities
Arlington, Texas • Fort Sam Houston, Texas • Lackland Air Force Base, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2014 · Synced Sep 26, 2026, 2:26 AM EDT
Not listed Not applicable Interventional

Impact of Supported Employment Versus Standard Vocational Rehabilitation in Veterans With Post-traumatic Stress Disorder

NCT00728325
View directory record Official record
Conditions
PTSD
Interventions
Supported Employment (SE), Standard Vocational Rehabilitation (VRP)
Behavioral
Lead sponsor
Tuscaloosa Research & Education Advancement Corporation
Other
Eligibility
19 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
3
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 4, 2013 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional

Evaluating Supplementing Residential Substance Use Treatment With Written Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD) and Substance Use Disorders (SUD)

NCT05536908
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Residential Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 26, 2026, 2:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Relief of Symptoms of Post-traumatic Stress for Victims of Gun Violence

NCT03916614
View directory record Official record
Conditions
PTSD, Stress, Psychological, Gunshot Wound
Interventions
Screening Tool for Relief of Trauma (START), standard of care
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 13, 2022 · Synced Sep 26, 2026, 2:26 AM EDT
Recruiting Not applicable Interventional

Multifaceted Intervention to Restore Resilience and Overcome Risk

NCT06988787
View directory record Official record
Conditions
Military Sexual Trauma, Intimate Partner Violence, Brain Injury, Post Traumatic Stress Disorder
Interventions
webSTAIR, ExpoTx, PsychoEd
Behavioral · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 20, 2026 · Synced Sep 26, 2026, 2:26 AM EDT