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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Refraction Clear all
Active, not recruiting Not applicable Interventional

Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear

NCT06009458
View directory record Official record
Conditions
Myopia
Interventions
Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
Device
Lead sponsor
Acuity Polymers, Inc.
Industry
Eligibility
7 Years and older
Enrollment
387 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
9
States / cities
Mission Viejo, California • Oakland, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 4, 2026, 2:19 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Handheld Device Compared With a Standard Eye Care Diagnostic Device in Measuring Ophthalmic Refraction

NCT04693247
View directory record Official record
Conditions
Refractive Errors, Vision Disorders
Interventions
EQ103
Device
Lead sponsor
EyeQue Corp.
Industry
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Newark, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2022 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Monofocal IOL Visual Outcomes When Targeting Mini Monovision

NCT05069415
View directory record Official record
Conditions
Cataract, Presbyopia
Interventions
Eyhance IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Sarasota, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

visuALL Field Analyzer (vFA) Compared to Standard Humphrey Automated Perimetry

NCT03804684
View directory record Official record
Conditions
Glaucoma, Open-Angle
Interventions
Standard Automatic Perimetry Humphrey Field Analyzer, visuALL Field Analyzer
Diagnostic Test
Lead sponsor
Wills Eye
Other
Eligibility
21 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Sep 4, 2026, 2:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Investigation on Assessing the Repeatability and Reproducibility of Central and Peripheral Refractive Error

NCT06209476
View directory record Official record
Conditions
Refractive Error
Interventions
Experimental
Diagnostic Test
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Sep 4, 2026, 2:19 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Corneal Sensation and Incidence of Dry Eye Post Refractive Cataract Extraction With FemtoSecond Laser

NCT01441895
View directory record Official record
Conditions
Cataract, Dry Eye
Interventions
Not listed
Lead sponsor
Ophthalmic Consultants of Long Island
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Rockville Centre, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2016 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Influence of DisCoVisc Ophthalmic Viscosurgical Device (OVD) on Intraoperative Aberrometry Readings

NCT03751033
View directory record Official record
Conditions
Cataract
Interventions
BSS, DiscoVisc
Device
Lead sponsor
Clinical Research Consultants, Inc.
Industry
Eligibility
22 Years to 95 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Los Angeles, California • Brecksville, Ohio • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Trial of Overminus Spectacle Therapy for Intermittent Exotropia

NCT02807350
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Overminus treatment, Non-overminus treatment
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 10 Years
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
59
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 50 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Safety and Effectiveness of the Calhoun Vision Light Adjustable Intraocular Lens (LAL)

NCT00845520
View directory record Official record
Conditions
Cataracts
Interventions
Lens implantation -1.00 D postop target, Lens implantation 0.00 D postop target
Device
Lead sponsor
Calhoun Vision, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
5
States / cities
Los Altos, California • Los Angeles, California • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of a Hand-held Device Plus Mobile App Versus Standard Eye Care Devices in Measuring Refractive Error of the Eye

NCT03929588
View directory record Official record
Conditions
Refractive Errors, Astigmatism
Interventions
Hand-held device supported by a mobile application, Phoropter, Autorefractor
Device
Lead sponsor
EyeQue Corp.
Industry
Eligibility
30 Years to 65 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Inglewood, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2022 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Toric Intraocular Lens Following Cataract Surgery

NCT01140477
View directory record Official record
Conditions
Cataract, Astigmatism
Interventions
Toric Accommodating Lens, Accommodating Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 7, 2014 · Synced Sep 4, 2026, 2:19 AM EDT
Terminated Phase 1 Interventional Results available

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Participants With Diabetic Macular Edema

NCT04292912
View directory record Official record
Conditions
Macular Edema
Interventions
GSK2798745
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
6
States / cities
Sacramento, California • Lake Worth, Florida • Winter Haven, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Sep 4, 2026, 2:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Proof of Concept Study for First-Sight Refractive Error Correction: Direct Comparison to Manifest Refraction and Autorefraction Results

NCT01342393
View directory record Official record
Conditions
Refractive Error
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 10, 2012 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

VisionApp - Refraction and Presbyopia

NCT07570602
View directory record Official record
Conditions
Presbyopia, Refractive Errors
Interventions
VisionApp
Device
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 4, 2026, 2:19 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Pediatric Refraction With SVOne Autorefractor

NCT02559271
View directory record Official record
Conditions
Ocular Refraction
Interventions
Not listed
Lead sponsor
Smart Vision Labs
Industry
Eligibility
5 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Sep 4, 2026, 2:19 AM EDT
Not yet recruiting Not applicable Interventional

Validation of the Vision Trainer Clinical Decision-Support Software

NCT07773753
View directory record Official record
Conditions
Myopia
Interventions
Software Trainer
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 4, 2026, 2:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Enhanced Housing Photoscreeners 2WIN and GoCheckKids Compared in Burma and Alaska

NCT04068129
View directory record Official record
Conditions
Amblyopia, Anisometropia
Interventions
photoscreen
Device
Lead sponsor
Alaska Blind Child Discovery
Other
Eligibility
6 Months to 40 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 4, 2026, 2:19 AM EDT
Recruiting Not applicable Interventional

Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2

NCT06934577
View directory record Official record
Conditions
Eye Diseases, Visual Impairment, Glaucoma
Interventions
Standard optometric examination, Technology enhanced eye disease detection protocol
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Microwave Treatment and Corneal Collagen Crosslinking for Keratoconus

NCT01672814
View directory record Official record
Conditions
Keratoconus
Interventions
riboflavin ophthalmic solution, Vedera KXS Microwave System
Drug · Device
Lead sponsor
Cornea and Laser Eye Institute
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Teaneck, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Timing of Low Vision Rehabilitation in Anti- Vascular Endothelial Growth Factor (VEGF) Therapy

NCT03065907
View directory record Official record
Conditions
Low Vision, Neovascular Age-related Macular Degeneration
Interventions
Vision rehabilitation
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 105 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2019 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Results available

Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism

NCT01852084
View directory record Official record
Conditions
Astigmatism
Interventions
enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Technology-based Eye Care Services (TECS) Compare

NCT02558712
View directory record Official record
Conditions
Cataract, Macular Degeneration, Glaucoma
Interventions
Technology-based Eye Care Services (TECS) Protocol
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2018 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

LFR-260 vs Traditional Phoropter in Visual Acuity Testing

NCT05259163
View directory record Official record
Conditions
Visual Acuity, Astigmatism, Anisometropia
Interventions
LFR-260 portable phoropter, Traditional phoropter (SOC)
Device
Lead sponsor
Evolution Optiks Limited
Industry
Eligibility
12 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Worcester, Massachusetts • Oyster Bay, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Sep 4, 2026, 2:19 AM EDT
Completed Not applicable Interventional

Post Marketing Clinical Study on the Efficacy of Lenses From a New Prescription Protocol

NCT07168564
View directory record Official record
Conditions
Ametropia, Refractive Error
Interventions
AVA lenses, Standard lenses
Device
Lead sponsor
Essilor International
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 4, 2026, 2:19 AM EDT