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ClinicalTrials.gov public records Last synced Oct 20, 2026, 8:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 75 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Refractive Error Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Myopia:the Role of Cone Opsin Mutations & Glasses That Control Axial Elongation

NCT01923675
View directory record Official record
Conditions
Myopia
Interventions
Spectacles with red-blocking tint, Spectacles with holographic diffuser and color neutral tint, Spectacles with holographic diffuser and red-blocking tint, Spectacles with color neutral tint
Other
Lead sponsor
University of Washington
Other
Eligibility
8 Years to 13 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 20, 2026, 8:23 AM EDT
Completed Not applicable Interventional Results available

Spectacles for Patients With Down Syndrome

NCT03367793
View directory record Official record
Conditions
Vision, Low
Interventions
Spectacles - Clinically Derived, Spectacles - Metric Technique #1 Derived, Spectacles - Metric Technique #2 Derived
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Oct 20, 2026, 8:23 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Direct Comparison of SVOne Obtained Refraction to Subjective Manifest Refraction

NCT03222661
View directory record Official record
Conditions
Refractive Errors
Interventions
Refraction
Diagnostic Test
Lead sponsor
Smart Vision Labs
Industry
Eligibility
12 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2017 · Synced Oct 20, 2026, 8:23 AM EDT
Completed No phase listed Observational

Gocheck Kids vs. Welch Allyn Spot Vision Screener

NCT04321538
View directory record Official record
Conditions
Amblyopia
Interventions
Gocheck Kids, Welch Allyn Spot Vision Screener, Physical Exam
Device · Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
1 Year to 7 Years
Enrollment
227 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 20, 2026, 8:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner

NCT01832883
View directory record Official record
Conditions
Amblyopia, Strabismus
Interventions
Pediatric Vision Scanner
Device
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
3 Years to 8 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 13, 2018 · Synced Oct 20, 2026, 8:23 AM EDT
Completed Not applicable Interventional

Binocular Vision Anomalies After Cataract and Refractive Surgery

NCT03592615
View directory record Official record
Conditions
Binocular Vision Disorder, Refractive Errors, Cataract
Interventions
cataract surgery, Corneal refractive surgery
Procedure
Lead sponsor
Salus University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 20, 2026, 8:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

First-Sight Refractive Error Correction in the Developing World

NCT01598818
View directory record Official record
Conditions
Vision Loss
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
7 Years to 50 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Oct 20, 2026, 8:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner

NCT01706991
View directory record Official record
Conditions
Amblyopia, Strabismus
Interventions
Pediatric Vision Scanner eye scan
Device
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
6 Months to 6 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2012 · Synced Oct 20, 2026, 8:23 AM EDT
Completed No phase listed Observational

Patient Reported Outcomes With LASIK: PROWL-2

NCT01655420
View directory record Official record
Conditions
Laser in Situ Keratomileusis
Interventions
LASIK
Procedure
Lead sponsor
Food and Drug Administration (FDA)
Federal
Eligibility
21 Years to 84 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
5
States / cities
Stanford, California • Indianapolis, Indiana • Overland Park, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2018 · Synced Oct 20, 2026, 8:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancement of Emmetropization in Highly Hyperopic Infants

NCT03669146
View directory record Official record
Conditions
Hyperopia
Interventions
Glasses
Device
Lead sponsor
Donald O Mutti, OD, PhD
Other
Eligibility
8 Weeks to 15 Weeks
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Oct 20, 2026, 8:23 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction

NCT05611294
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Topography Guided LASIK Surgery, Small Incision Lenticule Extraction Surgery
Device
Lead sponsor
Hoopes Vision
Other
Eligibility
22 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Draper, Utah
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Oct 20, 2026, 8:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Wavefront-Guided LASIK Correction of Hyperopic Refractive Errors

NCT01675479
View directory record Official record
Conditions
Hyperopia
Interventions
LASIK correction of hyperopic refractive errors
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
9
States / cities
Los Angeles, California • Miami, Florida • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 20, 2026, 8:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurolens Headache Study

NCT05070767
View directory record Official record
Conditions
Binocular Vision Disorder, Convergence Insufficiency, Headache, Computer Vision Syndrome
Interventions
Neurolens spectacle lens, Placebo spectacle lens
Device
Lead sponsor
Neurolens Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
10
States / cities
Phoenix, Arizona • Conyers, Georgia • Perry, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Oct 20, 2026, 8:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Screening Aid to Identify Corneas That May Have Pathologies or Other Conditions

NCT00396188
View directory record Official record
Conditions
Corneal Diseases
Interventions
Not listed
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
18 Years and older
Enrollment
769 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
4
States / cities
La Jolla, California • San Diego, California • Greenwood Village, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2015 · Synced Oct 20, 2026, 8:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of a Hand-held Device Plus Mobile App Versus Standard Eye Care Devices in Measuring Refractive Error of the Eye

NCT03929588
View directory record Official record
Conditions
Refractive Errors, Astigmatism
Interventions
Hand-held device supported by a mobile application, Phoropter, Autorefractor
Device
Lead sponsor
EyeQue Corp.
Industry
Eligibility
30 Years to 65 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Inglewood, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Oct 20, 2026, 8:23 AM EDT
Completed Not applicable Interventional

A Prospective Clinical Study to Evaluate the Repeatability of the Visibly Vision Test

NCT06812572
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Visibly Vision Test
Device
Lead sponsor
Visibly
Industry
Eligibility
22 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Harlingen, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 20, 2026, 8:23 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in Adults

NCT01547429
View directory record Official record
Conditions
Aphakia
Interventions
Artisan Aphakia Intraocular Lens
Device
Lead sponsor
Ophtec USA
Industry
Eligibility
22 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
17
States / cities
Beverly Hills, California • Los Angeles, California • Stratford, Connecticut + 14 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 20, 2026, 8:23 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Optical Defocus to Stimulate Eye Elongation in Hyperopia

NCT00950924
View directory record Official record
Conditions
Hyperopia, Refractive Error
Interventions
Simultaneous Vision Bifocal Soft Contact Lenses, Single Vision Soft Contact Lenses
Device
Lead sponsor
Aller, Thomas A., OD
Other
Eligibility
5 Years to 12 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
San Bruno, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 20, 2026, 8:23 AM EDT
Terminated Phase 1Phase 2 Interventional

Enhancement of Emmetropization in Hyperopic Infants

NCT00574717
View directory record Official record
Conditions
Hyperopia, Hypermetropia, Farsightedness
Interventions
Spectacles
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
8 Weeks to 20 Weeks
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2012 · Synced Oct 20, 2026, 8:23 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Spectacles Lens in Concussed Kids

NCT03123822
View directory record Official record
Conditions
Concussion, Mild, Convergence Insufficiency, Accommodation; Insufficiency
Interventions
Glasses
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
9 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Oct 20, 2026, 8:23 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Effects of Optical Blur on Performance and Comfort of Computer Users

NCT00318045
View directory record Official record
Conditions
Refractive Error
Interventions
Eyeglass lenses
Device
Lead sponsor
Vision Council of America
Other
Eligibility
19 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 25, 2006 · Synced Oct 20, 2026, 8:23 AM EDT
Completed No phase listed Observational

Prospective Evaluation of a Smartphone Application, GoCheckKids™, to Detect Amblyopia Risk Factors in Young Children

NCT03447171
View directory record Official record
Conditions
Amblyopia
Interventions
App Vision Screening
Device
Lead sponsor
Gobiquity Mobile Health
Industry
Eligibility
1 Year to 8 Years
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 20, 2026, 8:23 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia

NCT05124275
View directory record Official record
Conditions
Presbyopia
Interventions
Pilocarpine Ophthalmic Topical Cream, Dose 1, Pilocarpine Ophthalmic Topical Cream, Dose 2, Pilocarpine Ophthalmic Topical Cream, Dose 3, Placebo Ophthalmic Topical Cream
Drug
Lead sponsor
Glaukos Corporation
Industry
Eligibility
40 Years to 55 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
10
States / cities
Chandler, Arizona • Sun City, Arizona • Glendale, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Oct 20, 2026, 8:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Study to Evaluate Effectiveness of Digital Refraction

NCT03502863
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Digital refraction, Manual Refraction
Device · Other
Lead sponsor
Visibly
Industry
Eligibility
22 Years to 55 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
3
States / cities
Fort Lauderdale, Florida • Nashville, Tennessee • Harlingen, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2018 · Synced Oct 20, 2026, 8:23 AM EDT