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ClinicalTrials.gov public records Last synced Oct 20, 2026, 9:04 AM EDT

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Showing 49–72 of 75 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Refractive Error Clear all
Terminated Not applicable Interventional Results available

A Study Raindrop Near Vision Inlay in Presbyopes Implanted in Corneal Pockets

NCT03326869
View directory record Official record
Conditions
Presbyopia
Interventions
Raindrop Near Vision Inlay
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
41 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Panama City, Florida
Source: ClinicalTrials.gov public record
Updated Aug 10, 2020 · Synced Oct 20, 2026, 9:04 AM EDT
Completed No phase listed Observational

Measurement of Refractive Error in Pseudophakic Eyes Using an Autorefractor and a Wavefront Aberrometer

NCT06797856
View directory record Official record
Conditions
Measurement of Refractive Error
Interventions
Refractive Error
Diagnostic Test
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
40 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Oct 20, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Prospective Comparison of Alcon LADARVision Wavefront-guided LASIK Enhancement and Conventional LASIK Enhancement for the Correction of Residual Refractive Errors Following LASIK Procedures

NCT00413881
View directory record Official record
Conditions
Refractive Errors
Interventions
WAVEFRONT- GUIDED LASIK ENHANCEMENT, CONVENTIONAL LASIK ENHANCEMENT
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 14, 2010 · Synced Oct 20, 2026, 9:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Agreement and Precision Study of UNITY® DX and a Comparator Biometer

NCT06826599
View directory record Official record
Conditions
Normal Eyes, Abnormal Eyes
Interventions
Investigational Biometer, IOLMaster 700 Biometer
Device
Lead sponsor
Cylite Pty Ltd
Industry
Eligibility
22 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Woburn, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 20, 2026, 9:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses

NCT01058629
View directory record Official record
Conditions
Refractive Errors, Astigmatism
Interventions
SynergEyes A2 Hybrid Contact Lens
Device
Lead sponsor
SynergEyes, Inc.
Industry
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
10
States / cities
Campbell, California • Carlsbad, California • Encino, California + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2010 · Synced Oct 20, 2026, 9:04 AM EDT
Completed Not applicable Interventional Results available

Infant Aphakia Treatment Study (IATS)

NCT00212134
View directory record Official record
Conditions
Congenital Cataract
Interventions
Contact lens correction of aphakia, Intraocular lens implantation
Device
Lead sponsor
Stanford University
Other
Eligibility
28 Days to 210 Days
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2020
U.S. locations
13
States / cities
Palo Alto, California • Miami, Florida • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 20, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Spaeth/Richman Contrast Sensitivity Test

NCT01300949
View directory record Official record
Conditions
Glaucoma
Interventions
Spaeth/Richman Contrast Sensitivity Test, Pelli-Robson Contrast Sensitivity Chart
Diagnostic Test
Lead sponsor
Wills Eye
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Oct 20, 2026, 9:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Proof of Concept Study for First-Sight Refractive Error Correction: Direct Comparison to Manifest Refraction and Autorefraction Results

NCT01342393
View directory record Official record
Conditions
Refractive Error
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 11, 2012 · Synced Oct 20, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

LFR-260 vs Traditional Phoropter in Visual Acuity Testing

NCT05259163
View directory record Official record
Conditions
Visual Acuity, Astigmatism, Anisometropia
Interventions
LFR-260 portable phoropter, Traditional phoropter (SOC)
Device
Lead sponsor
Evolution Optiks Limited
Industry
Eligibility
12 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Worcester, Massachusetts • Oyster Bay, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Oct 20, 2026, 9:04 AM EDT
Completed Not applicable Interventional Results available

Bifocal Lenses In Nearsighted Kids

NCT02255474
View directory record Official record
Conditions
Refractive Errors
Interventions
Biofinity Multifocal D +1.50 add, Biofinity Multifocal D +2.50 add, Biofinity
Device
Lead sponsor
Ohio State University
Other
Eligibility
7 Years to 11 Years
Enrollment
294 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 20, 2026, 9:04 AM EDT
Not listed Not applicable Interventional

Study to Evaluate the Reliability, Validity and Safety of Subjective Mobile Refraction

NCT05049070
View directory record Official record
Conditions
Refractive Errors
Interventions
Mobile medical application to self administer a subjective refraction test, Standard of care refraction test
Diagnostic Test
Lead sponsor
1800 Contacts, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
349 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
12
States / cities
Beverly Hills, California • Petaluma, California • Pomona, California + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 20, 2026, 9:04 AM EDT
Completed Not applicable Interventional Results available

Base-in Prism Spectacles for Intermittent Exotropia

NCT03998670
View directory record Official record
Conditions
Exotropia Intermittent
Interventions
Prism Glasses, Non-Prism Glasses
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 13 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
28
States / cities
Birmingham, Alabama • Glendale, Arizona • Little Rock, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 20, 2026, 9:04 AM EDT
Terminated No phase listed Observational

Bilateral and Unilateral Amblyopia Treatment Study

NCT03780205
View directory record Official record
Conditions
Amblyopia
Interventions
Prescription glasses for bilateral amblyopia, Prescription glasses for unilateral amblyopia
Other
Lead sponsor
Salus University
Other
Eligibility
3 Years to 10 Years
Enrollment
1 participant
Timeline
2019 – 2020
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Oct 20, 2026, 9:04 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes

NCT07227714
View directory record Official record
Conditions
Cataract Surgery, Eye Care, Glasses, Primary Eye Care, Vision Center, Eyecare Visits
Interventions
Establishment of a vision center
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
150,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 20, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of the Accuracy of an Automated Refractor to Provide Well-tolerated Eyeglass Prescriptions

NCT06883032
View directory record Official record
Conditions
Refractive Errors
Interventions
AR Eyeglasses first, SR Eyeglasses second, SR Eyeglasses first, AR Eyeglasses second
Other
Lead sponsor
PlenOptika, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2025 · Synced Oct 20, 2026, 9:04 AM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Early Feasibility Study to Evaluate the AccuraSee in Correcting Residual Refractive Errors After Cataract Surgery

NCT05113979
View directory record Official record
Conditions
Refractive Errors
Interventions
AccuraSee IOPCL with +3.0D add
Device
Lead sponsor
OnPoint Vision Inc
Industry
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Oct 20, 2026, 9:04 AM EDT
Not yet recruiting Not applicable Interventional

The Emmetropization Via Accommodation (EVA) - II Study

NCT07838597
View directory record Official record
Conditions
Hyperopia, Farsightedness, Hypermetropia
Interventions
Experimental treatment arm
Combination Product
Lead sponsor
Ohio State University
Other
Eligibility
13 Weeks to 19 Weeks
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 20, 2026, 9:04 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Spectacle Prescribing in Early Childhood

NCT04728451
View directory record Official record
Conditions
Astigmatism Bilateral, Eyeglasses
Interventions
Spectacle wear support, Spectacles
Behavioral · Device
Lead sponsor
University of Arizona
Other
Eligibility
12 Months to 35 Months
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 20, 2026, 9:04 AM EDT
Completed No phase listed Observational

Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS Guidelines

NCT03668067
View directory record Official record
Conditions
Refractive Errors, Amblyopia, Strabismus, Development Delay
Interventions
2WIN photoscreener
Device
Lead sponsor
Alaska Blind Child Discovery
Other
Eligibility
1 Week to 90 Years
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Oct 20, 2026, 9:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Investigation on Assessing the Repeatability and Reproducibility of Central and Peripheral Refractive Error

NCT06209476
View directory record Official record
Conditions
Refractive Error
Interventions
Experimental
Diagnostic Test
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 20, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss

NCT03653715
View directory record Official record
Conditions
Presbyopia
Interventions
Clerio Vision LIRIC-modified Bifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Contact Lens, Clerio Vision Single Vision Contact Lens
Device
Lead sponsor
Clerio Vision, Inc.
Industry
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 19, 2019 · Synced Oct 20, 2026, 9:04 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

First-Sight Refractive Error Correction: Direct Comparison to Autorefraction Results in Children 7 to 18 Years of Age

NCT01365884
View directory record Official record
Conditions
Refractive Error
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
7 Years to 18 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Oct 20, 2026, 9:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treating Contact Lens Discomfort With Orthokeratology

NCT03566680
View directory record Official record
Conditions
Dry Eye, Contact Lens Complication
Interventions
Orthokeratology
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 45 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Oct 20, 2026, 9:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner

NCT01726842
View directory record Official record
Conditions
Amblyopia, Strabismus
Interventions
Pediatric Vision Scanner
Device
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
2 Years to 6 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 29, 2015 · Synced Oct 20, 2026, 9:04 AM EDT