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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Postoperative Pain
Interventions
Ropivacaine, Lidocaine
Drug
Lead sponsor
Jacques E. Chelly
Other
Eligibility
18 Years to 80 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES

NCT05688943
Conditions
Anesthesia, Tubal Ligation
Interventions
Spinal Anesthesia, General Anesthesia
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Therapeutic Epidural Patch Versus Pain Block in the Midface for Headache

NCT03112720
Conditions
Postdural Puncture Headache
Interventions
Epidural Blood Patch, Sphenopalatine Ganglion Block
Device · Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
13 Years to 92 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
2
States / cities
New Brunswick, New Jersey
Completed Phase 4 Interventional Accepts healthy volunteers

Combined Spinal-Epidural Versus Traditional Labor Epidural

NCT00151346
Conditions
Labour Pain
Interventions
Bupivacaine and Fentanyl (for CSE), Bupivacaine and Fentanyl (for traditional epidural)
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
New York, New York
Conditions
Friedreich Ataxia
Interventions
Spinal tap for CSF collection, Venipuncture for blood sample
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Urinary Incontinence, Urinary Incontinence,Stress
Interventions
Adjustable Continence Therapy for Women (ACT)
Device
Lead sponsor
Uromedica
Industry
Eligibility
22 Years and older · Female only
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2032
U.S. locations
2
States / cities
Denver, Colorado • Omaha, Nebraska
Conditions
Chronic Pain, Sciatica, Failed Back Surgery Syndrome
Interventions
Awake, Non-Awake
Procedure
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
4
States / cities
Bethlehem, Pennsylvania • Danville, Pennsylvania • Hershey, Pennsylvania + 1 more
Conditions
Osteoarthritis, Hip
Interventions
isobaric bupivacaine, hyperbaric bupivacaine, isobaric mepivacaine
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 84 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Bensalem, Pennsylvania • Philadelphia, Pennsylvania
Completed Not applicable Interventional

Imaging of Lymphatic Anomalies

NCT02744027
Conditions
Gorham Disease, Lymphatic Diseases, Lymphangiomatosis
Interventions
Dynamic Contrast Enhanced Magnetic Resonance Lymphangiography (DCMRL), Heavy Weighted T2 Imaging (T2W), Lymph Node Access
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Caesarean Delivery
Interventions
TAP Block, Ropivacaine, Acetaminophen, Morphine
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
3
States / cities
Boston, Massachusetts • Lebanon, New Hampshire
Conditions
Total Knee Arthroplasty (TKA)
Interventions
Total IntraVenous Anesthesia (TIVA), Spinal-Block, Electroencephalogram (EEG)
Combination Product · Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Cervical Incompetence
Interventions
Chloroprocaine, Bupivacaine
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 2 Interventional Results available

1% Chloroprocaine(PF) vs. Bupivacaine Spinals

NCT03324984
Conditions
Return of Motor and Sensory Blockade, Anesthesia, Spinal, Decrease Discharge Time Status Post Hemorrhoidectomy
Interventions
1% chloroprocaine, 0.75% bupivacaine
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Bladder Pain Syndrome
Interventions
Pulsed radiofrequency ablation
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older · Female only
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Renal Colic, Kidney Stone
Interventions
Erector Spinae Plane Block (ESPB), Ropivacaine
Procedure · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Joint Disease, Pain, Acute, Pain, Chronic
Interventions
Cymbalta, Placebo
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
25 Years to 75 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Postoperative Complications, Hip Fracture, Delirium
Interventions
General endotracheal anesthesia, Regional (spinal) Anesthesia
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Soft Tissue Sarcoma, Soft Tissue Tumor, Soft Tissue Tumor and/or Sarcoma
Interventions
Liposomal Bupivacaine
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Lysosomal Diseases, Gangliosidosis, GM1
Interventions
AAV9-GLB1, Abdominal ultrasound, Rituximab, Sirolimus, Methylprednisolone, Prednisone, Audiology assessment with ABR, Bone density scan (DEXA), Electrocardiogram (EKG), Echocardiogram, Electroencephalogram (EEG) awake and extended overnight, Laboratory tests, Lumbar puncture, Brain MRI/MRS/fMRI, Neurocognitive testing, Neurology exam, PICC or other Central line placement, Skeletal survey, Skin biopsy, Speech and modified barium swallow study, Ophthalmology exam
Biological · Procedure · Drug + 3 more
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
6 Months to 12 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Inguinal Hernia
Interventions
Regional Anesthesia, General Anesthesia
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 60 Weeks
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
10
States / cities
Aurora, Colorado • Chicago, Illinois • Iowa City, Iowa + 7 more
Completed Not applicable Interventional

Regional Anesthesia EMG Study

NCT06287151
Conditions
Surgery
Interventions
BlockSynop surface electromyography device, Clonidine, Sevoflurane
Device · Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
0 Years to 5 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Paracervical Block for Pain Control With Osmotic Dilator Placement

NCT02354092
Conditions
Abortion Late, Pain
Interventions
Local anesthetic for tenaculum placement, Sham, Paracervical Block, Dilator Placement, Post-procedural assessment, Preprocedural pain control
Procedure · Behavioral · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
2
States / cities
San Diego, California
Conditions
Post Operative Pain, Spinal Fusion
Interventions
Bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride and Epinephrine Injection
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Persistent Spinal Pain Syndrome
Interventions
Pain pump, Bupivacain 0.625%/Fentanyl 2mcg/ml, Spinal Cord Stimulator (SCS)
Device · Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
30 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio