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Showing 25–48 of 665 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Results available

Continuous Local Anesthetic Infusion Following Hernia Repair

NCT01804114
Conditions
Ventral Hernia
Interventions
Pain management following hernia repair, Placebo for pain management following hernia repair
Procedure
Lead sponsor
Endeavor Health
Other
Eligibility
19 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Evanston, Illinois
Conditions
Opioid Use, Unspecified
Interventions
Ropivacaine, Dexmedetomidine, Dexamethasone
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Paracervical Block for Pain Control With Osmotic Dilator Placement

NCT02354092
Conditions
Abortion Late, Pain
Interventions
Local anesthetic for tenaculum placement, Sham, Paracervical Block, Dilator Placement, Post-procedural assessment, Preprocedural pain control
Procedure · Behavioral · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
2
States / cities
San Diego, California
Conditions
Pain, Postoperative
Interventions
Trans-incisional rectus sheath block, Laparoscopic guided rectus sheath block, Ropivacaine
Procedure · Drug
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
10 Years to 21 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
St. Petersburg, Florida
Conditions
Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Interventions
bilateral transforaminal epidural steroid injections
Drug
Lead sponsor
Marshfield Clinic Research Foundation
Other
Eligibility
40 Years to 90 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Marshfield, Wisconsin
Completed Phase 3 Interventional Results available

Bupivacaine Effectiveness and Safety in SABER® Trial

NCT01052012
Conditions
Postoperative Pain, Abdominal Surgery
Interventions
SABER-Bupivacaine, Bupivacaine HCl, SABER-Placebo
Drug
Lead sponsor
Durect
Industry
Eligibility
18 Years and older
Enrollment
331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
22
States / cities
Birmingham, Alabama • Florence, Alabama • Mobile, Alabama + 18 more
Completed Phase 4 Interventional Accepts healthy volunteers

EMLA Cream as Analgesic for Outpatient Gynecological Procedures

NCT05970354
Conditions
Pain
Interventions
EMLA Cream, VersaPro Cream Base for Compounding
Drug
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Charleston, West Virginia
Not listed Not applicable Interventional Accepts healthy volunteers

Pain Perception: Lidocaine Rate/Temp/Buffer

NCT02823002
Conditions
Pain
Interventions
Slow, Room Temperature Injection, Rapid, Room Temperature Injection, Slow, Warm Temperature Injection, Rapid, Warm Temperature Injection, Buffered Injection, Non-Buffered Injection, Lidocaine, Buffer
Procedure · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery

NCT02052557
Conditions
Post-operative Pain, Colon Cancer, Diverticulitis
Interventions
Bupivacaine, Bupivacaine liposome suspension
Drug
Lead sponsor
Des Moines University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Des Moines, Iowa
Conditions
Congenital Heart Defect, Congenital Heart Disease, Anesthesia, Local, Opioid Use
Interventions
Bilateral Erector Spinae Plane Block (ESPB)
Procedure
Lead sponsor
Stanford University
Other
Eligibility
0 Years to 99 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Shoulder Surgery, Obesity
Interventions
Ultrasound-Guided Interscalene Brachial Plexus Block, Phrenic-Sparing Block Combination (Experimental), Bupivacaine HCl 0.5% Injectable Solution, Dexamethasone 4mg
Procedure · Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Results available

Steroids Versus Gabapentin

NCT01495923
Conditions
Sciatica, Radiculopathy
Interventions
epidural steroid injection, Sham epidural steroid injection, Gabapentin, Placebo gabapentin
Procedure · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
17 Years to 100 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
3
States / cities
San Diego, California • Baltimore, Maryland • Bethesda, Maryland
Completed Phase 4 Interventional Results available

Interscalene Block Versus Superior Trunk Block

NCT03272139
Conditions
Joint Disease, Pain, Pain, Acute, Pain, Chronic
Interventions
Bupivacaine, Ultrasound
Drug · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Surgery of Right Upper Extremity
Interventions
Ultrasound Imaging, Supraclavicular Block, Bedside Negative Inspiratory Force Meter
Diagnostic Test · Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 105 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Post-operative Pain Management
Interventions
Bupivacaine 0.25% Injectable Solution, Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg, Bupivacaine 0.25% Injectable Solution, Magnesium Sulfate 200 mg, Buprenorphine 300 mcg
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 100 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pontiac, Michigan
Conditions
Heart Failure, Pulmonary Arterial Hypertension
Interventions
right heart catheterization
Diagnostic Test
Lead sponsor
Silverleaf Medical Sciences INC
Industry
Eligibility
20 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Uterine Fibroids, Polyps
Interventions
Hysteroscopic Morcellator
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
5
States / cities
Phoenix, Arizona • Boca Raton, Florida • Detroit, Michigan + 2 more
Conditions
Pain, Postoperative, Surgical Procedure, Unspecified
Interventions
Liposomal Bupivacaine, Bupivacaine HCl
Drug
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Pectus Excavatum
Interventions
Patient controlled analgesia, Continuous thoracic epidural infusions, Continuous paravertebral blockade
Device · Procedure
Lead sponsor
Ralph Beltran
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Recruiting Not applicable Interventional

RFA for Superficial Lipomas

NCT06903208
Conditions
Lipoma
Interventions
STARMed VIVA Combo RF System
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Cardiogenic Shock
Interventions
Interscalene Block, PECS II Block, Superficial Cervical Plexus Block
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Conditions
Pain Management
Interventions
Local anaesthetic, Pudendal Nerve Block plus anesthesia
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Nephrectomy, Partial Nephrectomy, Incision Site Discomfort
Interventions
Ropivacaine, Normal saline
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Heart Rate, Blood Pressure, Blood Loss During Surgery, Surgical Field
Interventions
Not listed
Lead sponsor
Loma Linda University
Other
Eligibility
16 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Loma Linda, California