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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Regional block Clear all
Recruiting Phase 4 Interventional Accepts healthy volunteers

Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees

NCT06590402
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Medial Patellofemoral Ligament Reconstruction
Interventions
Bupivacaine, Dexamethasone in Adductor Canal Block, Bupivacaine, Dexamethasone in Anterior Femoral Cutaneous Nerve Block
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
8 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Sep 21, 2026, 1:01 PM EDT
Recruiting Phase 1Phase 2 Interventional

Minimally Invasive Esophagectomy Pain Control Trial

NCT05906134
View directory record Official record
Conditions
Postoperative Pain, Acute, Postoperative Complications
Interventions
Local intercostal nerve block, Cryo-analgesia and intercostal nerve block, Serratus plane catheter blocks and intercostal nerve blocks, Thoracic epidural catheter
Procedure
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional

Patient Positioning and Airway Management During ERCP

NCT02850887
View directory record Official record
Conditions
Airway Management
Interventions
general endotracheal anesthesia, deep sedation without endotracheal intubation
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Results available

Postoperative Knee Strength Following Total Knee Replacement: A Double-Blinded Randomized Comparison Study

NCT01620047
View directory record Official record
Conditions
Total Knee Replacement, Primary Knee Arthroplasty
Interventions
Fentanyl, Ropivacaine
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 10, 2013 · Synced Sep 21, 2026, 1:01 PM EDT
Not yet recruiting Not applicable Interventional

Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome

NCT06953661
View directory record Official record
Conditions
Postural Tachycardia Syndrome
Interventions
Stellate ganglion block, Sham injection of saline, Ropivacaine, Normal saline
Procedure · Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 21, 2026, 1:01 PM EDT
Not listed Phase 2 Interventional

Study to Determine if Pre- and Post- Operative TAP Catheters With Ropivacaine Versus Placebo Affects Anesthetic, Narcotic Dosing, and Pain Scores

NCT03149783
View directory record Official record
Conditions
Pain, Postoperative, Delirium, Anesthesia, Local
Interventions
Ropivacaine HCL, sodium chloride
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 26, 2021 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Phase 4 Interventional Results available

Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?

NCT03326999
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Rheumatism
Interventions
Obturator nerve regional block, Adductor canal regional block, Saline
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 29, 2020 · Synced Sep 21, 2026, 1:01 PM EDT
Terminated Not applicable Interventional

Adductor Canal Block (ACB) vs Femoral Nerve Block (FNB) in Revision Total Knee Arthroplasty

NCT03697538
View directory record Official record
Conditions
Revision Total Knee Arthroplasty
Interventions
Nerve Block for pain control post-revision total knee arthroplasty
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 6, 2022 · Synced Sep 21, 2026, 1:01 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block

NCT05868993
View directory record Official record
Conditions
Post Operative Pain
Interventions
Dose of 0.5% Ropivacaine
Drug
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Phase 4 Interventional Results available

A Study Comparing Fascia Iliaca Blockade vs Extracapsular Local Field Infiltration With Liposomal Bupivacaine

NCT04114058
View directory record Official record
Conditions
Femoro Acetabular Impingement
Interventions
liposomal bupivicaine, Fascia iliaca blockade
Drug · Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2021 · Synced Sep 21, 2026, 1:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty

NCT02904993
View directory record Official record
Conditions
Degenerative Joint Disease
Interventions
L2 paravertebral block, periarticular injection group
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 15, 2016 · Synced Sep 21, 2026, 1:01 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain

NCT05386693
View directory record Official record
Conditions
Hernia, Inguinal, Chronic Postoperative Pain
Interventions
Ilioinguinal nerve block
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 21, 2026, 1:01 PM EDT
Terminated Phase 4 Interventional

iPACK Block With Dexamethasone For Total Knee Replacement

NCT04917055
View directory record Official record
Conditions
Knee Osteoarthritis, Acute Pain, Anesthesia, Local, Regional Anesthesia
Interventions
ropivacaine 0.25% with epinephrine and 6mg dexamethasone, Saline
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2023 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Phase 4 Interventional Results available

Truncal Ultrasound Guided Regional Anesthesia for Implantation and Revision of Automatic Implantable Cardioverter Defibrillators (AICDs) and Pacemakers in Pediatric Patients

NCT04184349
View directory record Official record
Conditions
Analgesia After Pacemaker, AICDS Implantation Pediatrics
Interventions
LA group, B Group
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
0 Years to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 21, 2026, 1:01 PM EDT
Completed No phase listed Observational

Role of Brain Region Changes in Tactile (Touch) Ability Following Nerve Block

NCT00357058
View directory record Official record
Conditions
Tactile Spatial Acuity, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 21, 2026, 1:01 PM EDT
Terminated Not applicable Interventional

Prevention of Phantom Limb Pain After Transtibial Amputation

NCT01626755
View directory record Official record
Conditions
Phantom Limb Pain, Chronic Pain, Prevention
Interventions
Sciatic name block
Procedure
Lead sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional

Optimizing Catheter Insertion Technique for Ultrasound-guided Continuous Peripheral Nerve Blocks

NCT01459523
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Proximal placement, Short axis ultrasound, Long axis, Distal placement
Procedure
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Phase 4 Interventional Results available

Fascia Iliaca Blocks for Pain Control After Total Hip Arthroplasty

NCT03375112
View directory record Official record
Conditions
Arthritis of Hip
Interventions
Fascia iliaca compartment block, Placebo, Bupivacaine
Procedure · Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Phase 2 Interventional

Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic

NCT01662401
View directory record Official record
Conditions
Postoperative Pain
Interventions
Bupivacaine
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
6 Years to 18 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2013 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Results available

Adductor Canal Block for Total Knee Arthroplasty

NCT02453360
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee, Pain, Postoperative
Interventions
Adductor Canal Block, Adductor Canal Block
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 7, 2019 · Synced Sep 21, 2026, 1:01 PM EDT
Terminated Phase 3 Interventional Results available

A Prospective Controlled Treatment Trial for Post-Traumatic Headaches

NCT03007420
View directory record Official record
Conditions
Post-Traumatic Headaches
Interventions
Occipital Nerve Block (ONB) using lidocaine and dexamethosone, Cervical Medial Branch Block (CMBB) using lidocaine and dexamethosone
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 21, 2026, 1:01 PM EDT
Recruiting Not applicable Interventional

Noninvasive Thalamocortical Neuromodulation With Low-Intensity Focused Ultrasound for Persistent Developmental Stuttering

NCT07668882
View directory record Official record
Conditions
Stuttering, Developmental Stuttering
Interventions
High DC LIFU, Sham
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 21, 2026, 1:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes of Buffered vs. Non-Buffered Lidocaine

NCT02620683
View directory record Official record
Conditions
Blood Levels of Buffered vs Non-buffered Lidocaine, Anesthetics, Local
Interventions
Lidocaine
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 30 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 21, 2026, 1:01 PM EDT
Recruiting Not applicable Interventional

BiOfeedback, Online for Sibilant Treatment

NCT07041723
View directory record Official record
Conditions
Speech Sound Disorder
Interventions
Visual-acoustic biofeedback for Sibilants
Behavioral
Lead sponsor
Montclair State University
Other
Eligibility
8 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bloomfield, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 21, 2026, 1:01 PM EDT