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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Resistance Exercise with Blood Flow Restriction Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Eccentric Resistance Training With Blood Flow Restriction on Muscle Function

NCT04977804
View directory record Official record
Conditions
Blood Flow Restriction
Interventions
Exercise, Eccentric plus blood-flow restriction
Other
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Sep 11, 2026, 12:02 AM EDT
Terminated Not applicable Interventional

Blood Flow Restriction Training in Rehabilitation Patients

NCT02174770
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Volumetric Muscle Loss, Chronic Thigh Muscle Weakness, Knee Arthroscopy
Interventions
Blood Flow Restriction (BFR) Training, Standard ACSM-guided strength training
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Sep 11, 2026, 12:02 AM EDT
Completed Not applicable Interventional Results available

Low Load Resistance Training Using Blood Flow Restriction for People With Multiple Sclerosis

NCT04633759
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Blood Flow Restriction Exercise
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 11, 2026, 12:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Minimal Equipment Training Approach to Improve Warfighter Performance

NCT05003778
View directory record Official record
Conditions
Healthy, Military Operations
Interventions
Traditional equipment resistance training, Minimal equipment resistance training, Blood flow restriction training
Other
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 35 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 11, 2026, 12:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

BFR and Muscle Mitochondrial Oxidative Capacity

NCT03723226
View directory record Official record
Conditions
Mitochondria, Strength, Hypertrophy
Interventions
Low Load Resistance Exercise, Low Load Resistance Exercise + BFR
Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Sep 11, 2026, 12:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Upper- and Lower-body Resistance Exercise With and Without Blood Flow Restriction on Hemodynamics and Vascular Function

NCT03225898
View directory record Official record
Conditions
Endothelial Dysfunction, Autonomic Dysfunction
Interventions
Resistance Exercise with Blood Flow Restriction, High-intensity Resistance Exercise
Other
Lead sponsor
Kent State University
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Kent, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2017 · Synced Sep 11, 2026, 12:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training for People With Disabilities

NCT06441422
View directory record Official record
Conditions
Weakness, Muscle
Interventions
Blood flow restriction training, No blood flow restriction training
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 11, 2026, 12:02 AM EDT
Terminated Not applicable Interventional Results available

Blood Flow Restriction Training in ACL Surgery

NCT05245864
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries
Interventions
blood flow restriction, physical therapy standard of care
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 34 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 11, 2026, 12:02 AM EDT
Terminated Not applicable Interventional

Comparison of Training Load With/Out Blood Flow Restriction Training in Rheumatoid Populations

NCT04309227
View directory record Official record
Conditions
Rheumatoid Arthritis, Myositis, Osteoarthritis, Weakness, Muscle
Interventions
Strength Training
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 85 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 21, 2024 · Synced Sep 11, 2026, 12:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis

NCT01440972
View directory record Official record
Conditions
Knee Osteoarthritis, Symptomatic Knee Osteoarthritis
Interventions
partial blood flow restriction (PBFR), low intensity resistance training
Other
Lead sponsor
University of Iowa
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 4, 2016 · Synced Sep 11, 2026, 12:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training on Upper Extremity Grip Strength

NCT06535373
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Blood flow restriction
Other
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Sep 11, 2026, 12:02 AM EDT
Enrolling by invitation Not applicable Interventional

Blood Flow Restriction for Ulnar Sided Wrist Pain

NCT06963671
View directory record Official record
Conditions
Ulnar Wrist Pain
Interventions
Blood Flow Restriction
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 11, 2026, 12:02 AM EDT
Recruiting Not applicable Interventional

Blood Flow Restriction for Optimizing Balance in Parkinson's Disease

NCT06508801
View directory record Official record
Conditions
Parkinson's Disease and Parkinsonism
Interventions
Blood flow restriction training, Instability Resistance Training
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
40 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 11, 2026, 12:02 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Resistance Exercise and Cardiac Cycle Dynamics

NCT07344740
View directory record Official record
Conditions
Cardiac
Interventions
Blood flow restriction resistance exercise
Behavioral
Lead sponsor
Montclair State University
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Montclair, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 11, 2026, 12:02 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Exploring Blood Flow Restriction as an Accessible Fitness Solution for Healthy Aging in Seniors

NCT07460609
View directory record Official record
Conditions
Healthy Ageing
Interventions
Blood Flow Restriction Training Exercise, Health Education
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 11, 2026, 12:02 AM EDT
Recruiting Not applicable Interventional

Blood Flow Restriction And Veterans With MS

NCT05433103
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Low-Load Exercise with Blood Flow Restriction, Low-Load Exercise Control Group
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 11, 2026, 12:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Activation With Acute Bouts of Blood Flow Restricted Resistance Exercise

NCT05586451
View directory record Official record
Conditions
Muscle, Acute Exercise
Interventions
Traditional High Load Resistance Exercise (HLRE), Low Load Resistance Exercise with Blood Flow Restriction (LLBFR), Moderate Load Resistance Exercise with Blood Flow Restriction (MLBFR)
Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 11, 2026, 12:02 AM EDT
Completed Not applicable Interventional

Blood Flow Restriction Exercise Study

NCT02868021
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Strength testing, Short Physical Performance Battery (SPPB), Six-minute walk (SMW), Numerical pain scale, Self-assessed function, Muscle biopsies, Determination of 1 Repetition Maximum (1-RM), Blood flow restriction exercise, Borg CR10 scale
Device · Behavioral · Procedure
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Sep 11, 2026, 12:02 AM EDT
Completed Not applicable Interventional

Blood Flow Restriction Exercise for Those With SCI

NCT04889092
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Blood Flow Restriction exercise, Traditional resistance exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 11, 2026, 12:02 AM EDT
Withdrawn Not applicable Interventional

Blood Flow Restriction Training Following Glenoid Labral Repair

NCT03675620
View directory record Official record
Conditions
Glenoid Labrum Tear
Interventions
BFR, Standard Rehabilitation
Device · Other
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Feb 5, 2024 · Synced Sep 11, 2026, 12:02 AM EDT
Active, not recruiting Not applicable Interventional

Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair

NCT07498166
View directory record Official record
Conditions
Achilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow Restriction
Interventions
Blood Flow Restriction Resistance Training (BFR-RT), Sham Blood Flow Restriction, Standard Physical Therapy
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 11, 2026, 12:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Training Versus Standard Physical Therapy After Shoulder Stabilization Surgery

NCT05506072
View directory record Official record
Conditions
Anterior Shoulder Dislocation, Recurrent Shoulder Dislocation, Shoulder Subluxation, Surgery
Interventions
Blood flow restriction therapy, Standard Physical Thearapy
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
17 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Sep 11, 2026, 12:02 AM EDT
Withdrawn Not applicable Interventional

The Effect of Low-Intensity Blood Flow Restriction Therapy on the Management of Acute Ankle Sprains

NCT05596162
View directory record Official record
Conditions
Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree, Musculoskeletal Injury
Interventions
Blood Flow Restriction Therapy, Standard Physical Therapy
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Sep 11, 2026, 12:02 AM EDT
Withdrawn Not applicable Interventional

BFRT vs Standard PT After Total Knee Arthroplasty

NCT04366336
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Blood Flow Restriction Training, Standard Physical Therapy
Procedure
Lead sponsor
Norton Healthcare
Other
Eligibility
50 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 6, 2022 · Synced Sep 11, 2026, 12:02 AM EDT