Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 382 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Cardiovascular Disease, Obesity, Physical Disability
Interventions
Caloric restriction, Aerobic Training, Resistance Training
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 79 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Kernersville, North Carolina • Winston-Salem, North Carolina
Conditions
Breast Cancer, Prehabilitation, Physical Activity, Surgery
Interventions
Exercise, Prehabilitation Education
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Obesity, Cardiovascular Diseases
Interventions
Diet, Diet Plus Aerobic Training, Diet plus Resistance Training
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years to 55 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Exercise on Young Adult Women With ACEs: an Integrative Pilot Study

NCT03521401
Conditions
Life Experiences
Interventions
Exercise
Behavioral
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 29 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stillwater, Oklahoma
Conditions
Obesity
Interventions
Exercise program, Nutrition, WLS
Behavioral · Dietary Supplement · Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
55 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 3 Interventional Accepts healthy volunteers

Exercise and Physical Fitness for Persons With Knee Osteoarthritis

NCT00265447
Conditions
Knee Osteoarthritis
Interventions
Strength training, Aerobic conditioning, Delayed exercise
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
50 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors

NCT04221750
Conditions
Frailty, Sarcopenic Obesity, Aging
Interventions
Lifestyle therapy, Metformin Hydrochloride, Placebo, Healthy Lifestyle
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years to 85 Years
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Houston, Texas
Conditions
Lymphoma, Leukemia, Myeloma
Interventions
Resistance Training, Aerobic Exercise, Optional Aerobic Exercise Procedure, Optional In-Person Exercise Sessions
Behavioral · Radiation
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Completed Not applicable Interventional Accepts healthy volunteers

The Insulin Sensitivity Using Aerobic Interval Conditioning

NCT01286922
Conditions
Pre-diabetes
Interventions
Behavioral: exercise
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
30 Years to 60 Years · Male only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Physical Activity, Psychosocial Stressors
Interventions
Physical Activity for Life (PAL)
Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
65 Years to 100 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Uniontown, Alabama
Conditions
Aging, Blood Pressure, Endothelial Dysfunction, Hypertension
Interventions
High-resistance inspiratory muscle strength training, Aerobic exercise
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boulder, Colorado
Conditions
Type 2 Diabetes Mellitus
Interventions
10-week exercise program on HA accumulation
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
40 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Conditions
Intellectual Disability, Mild to Moderate
Interventions
Cooking Skills, Physical Activity
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 30 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Mobility Disability
Interventions
(-)-Epicatechin-rich cocoa supplementation combined with exercise training, Placebo combined with exercise training
Combination Product
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Active, not recruiting Not applicable Interventional Results available

A Supervised Prehabilitation Program for Patients With Pancreatic Cancer

NCT05692323
Conditions
Pancreas Cancer
Interventions
PREHAB
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Results available

Strength Training and Endurance Exercise for LIFE

NCT02101060
Conditions
HIV
Interventions
exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Baltimore, Maryland • Salem, Virginia
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Brown Adipose Tissue Pilot

NCT03793127
Conditions
Aging
Interventions
Maximal oxygen consumption (V02 max), Brown adipose tissue (BAT) imaging, Muscle function testing
Other
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
20 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Exercise
Interventions
High-Intensity Functional Training (HIFT), Moderate-Intensity Continuous Training (MICT)
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 35 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Coral Gables, Florida
Conditions
Aortic Dissection
Interventions
Supervised Exercise Regiment
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Baltimore, Maryland
Conditions
Concussion
Interventions
Vestibular Rehabilitation, Traditional Protocol
Other
Lead sponsor
Beth Marschner
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minot, North Dakota
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

Combination Gerotherapeutic Interventions for Healthspan Improvement

NCT07475546
Conditions
Healthspan Improvement, Aging, Longevity
Interventions
Rapamycin, Naltrexone, Metformin, NAD+, GSH, Infinite Supplement, Placebo/control, B12, Intervention: Guided Meditation Program, Control: Podcast Listening Activity, Control: Standard Exercise Regimen, Intervention: Structured Exercise Program
Drug · Dietary Supplement · Behavioral
Lead sponsor
AgelessRx
Industry
Eligibility
60 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Type 2 Diabetes, Muscular Atrophy, Sedentary Behavior, Exercise, Pre-diabetes
Interventions
Bed Rest Intervention, Exercise Program
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
60 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Responsiveness to Acute Changes in Exercise and Relaxation (RACER) Trial

NCT03702712
Conditions
Breast Cancer
Interventions
Aerobic Exercise and Relaxation, Aerobic Exercise Only, Relaxation Only
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 120 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Recruiting Not applicable Interventional Accepts healthy volunteers

Combating Alzheimer's Through Sleep and Exercise

NCT04855630
Conditions
Dementia, Mild Cognitive Impairment (MCI), Cognitively Unimpaired, Alzheimer's Dementia (AD)
Interventions
Elemind Neuromodulation Headband, Exercise Routine
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
55 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Miami, Florida