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ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:26 AM EDT

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Showing 433–456 of 2,448 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 1 Interventional

A Phase 1, Multicenter, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of E6201 in Subjects With Advanced Solid Tumors

NCT00794781
View directory record Official record
Conditions
Advanced Solid Tumors
Interventions
E6201
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
12
States / cities
Scottsdale, Arizona • Los Angeles, California • Las Vegas, Nevada + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2022 · Synced Oct 22, 2026, 4:26 AM EDT
Completed Phase 2 Interventional

Temozolomide in Treating Patients With Solid Tumors That Have Spread to the Brain

NCT00012116
View directory record Official record
Conditions
Metastatic Cancer
Interventions
temozolomide
Drug
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2020 · Synced Oct 22, 2026, 4:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predicting Cognitive and Emotional Health From Neurocircuitry Following TBI

NCT01803048
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
20 Years to 45 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 22, 2026, 4:26 AM EDT
Terminated Phase 1 Interventional

ITIL-306 in Advanced Solid Tumors

NCT05397093
View directory record Official record
Conditions
Epithelial Ovarian Cancer, Non-small Cell Lung Cancer, Renal Cell Carcinoma
Interventions
ITIL-306
Biological
Lead sponsor
Instil Bio
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
St Louis, Missouri • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 22, 2026, 4:26 AM EDT
Completed Phase 2 Interventional Results available

Qsymia as an Adjunct to Surgical Therapy in the Superobese

NCT02301416
View directory record Official record
Conditions
Obesity, Metabolic Surgery, Weight Loss, Bariatric Surgery Procedures
Interventions
Phentermine/topiramate, low calorie diet
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 22, 2026, 4:26 AM EDT
Completed No phase listed Observational

Imaging Studies With GE C-Hawk Gamma Camera Compared to Routine Clinical Exam

NCT00256581
View directory record Official record
Conditions
Coronary Artery Disease, Chest Pain
Interventions
Additional rest and stress image sets on new camera
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 29, 2012 · Synced Oct 22, 2026, 4:26 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation of the Fear Extinction Circuit Using Temporally and Anatomically Specific TMS in Humans

NCT05368987
View directory record Official record
Conditions
PTSD
Interventions
Transcranial magnetic stimulation (TMS), Fear Conditioning and Extinction Paradigm
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 22, 2026, 4:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project REST: Regulation of Eating and Sleep Topography

NCT04057716
View directory record Official record
Conditions
Obesity, Childhood, Binge Eating, Sleep, Self-regulation
Interventions
Sleep restriction, Sleep extension
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
8 Years to 12 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 22, 2026, 4:26 AM EDT
Not yet recruiting Not applicable Interventional

Below-the-Knee Interventions for Limb Salvage: Use of Multifunctional Angioplasty Balloon Catheters

NCT06906055
View directory record Official record
Conditions
Peripheral Arterial Disease Below the Knee, Peripheral Arterial Disease, Rutherford 4 and 5 with Possibility to Improve Vascularization
Interventions
Multicath, Standard of Care (SOC)
Device
Lead sponsor
Summa Therapeutics, LLC
Industry
Eligibility
18 Years to 120 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Vineland, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 22, 2026, 4:26 AM EDT
Terminated Phase 3 Interventional Results available

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

NCT01111565
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Escitalopram, Aripiprazole
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
15
States / cities
Tucson, Arizona • Chino, California • Riverside, California + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2021 · Synced Oct 22, 2026, 4:26 AM EDT
Terminated Not applicable Interventional

Functional Magnetic Resonance Imaging (fMRI) Vascular Reactivity in Cerebral Cavernous Malformations (CCM)

NCT05298709
View directory record Official record
Conditions
Cerebral Cavernous Malformation
Interventions
Hyperventilation and CO2 challenge
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Oct 22, 2026, 4:26 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Hookah Smoking, Carbon Monoxide, and Coronary Endothelial Function

NCT03166787
View directory record Official record
Conditions
Smoking, Endothelial Dysfunction
Interventions
Charcoal hookah, E-coal hookah, Cigarette, Carbon Monoxide inhalation, Room Air inhalation, vitamin C, tadalafil
Other · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
21 Years to 49 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2021 · Synced Oct 22, 2026, 4:26 AM EDT
Active, not recruiting Not applicable Interventional

Improving Cardiac Rehabilitation Exercise Using Target Heart Rate Trial

NCT05925634
View directory record Official record
Conditions
Myocardial Infarction, Coronary Artery Bypass, Percutaneous Coronary Intervention, Heart Failure, Cardiac Valve Surgery
Interventions
RPE (usual care), GXT+THHR (intervention)
Behavioral
Lead sponsor
Baystate Medical Center
Other
Eligibility
60 Years to 99 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Springfield, Massachusetts • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 22, 2026, 4:26 AM EDT
Not listed No phase listed Observational

Advanced MRI In Acute Military TBI

NCT01313130
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Oct 22, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Concussion Treatment in Older Adults

NCT05849064
View directory record Official record
Conditions
Concussion, Mild
Interventions
Behavioral Control, Targeted Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years to 99 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 22, 2026, 4:26 AM EDT
Completed Not applicable Interventional Results available

Research on Expecting Moms and Sleep Therapy

NCT02805998
View directory record Official record
Conditions
Insomnia
Interventions
Web-based CBT-I, Treatment as Usual
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 25, 2024 · Synced Oct 22, 2026, 4:26 AM EDT
Completed No phase listed Observational

Assessment of Ability of Breath Hold for Left-sided Breast Cancer Radiation Therapy to Reduce Side Effects to Heart

NCT01849614
View directory record Official record
Conditions
Breast Cancer
Interventions
Cardiac SPECT perfusion scan
Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 12, 2016 · Synced Oct 22, 2026, 4:26 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Exercise in College Students With ADHD

NCT03666416
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Effects of; Exertion, Working Memory, Change in Sustained Attention
Interventions
Sprint Interval Training
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
18 Years to 29 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Oct 22, 2026, 4:26 AM EDT
Completed Phase 4 Interventional

A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear

NCT07054606
View directory record Official record
Conditions
Dry Eye
Interventions
Perfluorohexyloctane ophthalmic solution
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
6
States / cities
San Diego, California • Longwood, Florida • Pittsburg, Kansas + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 22, 2026, 4:26 AM EDT
Active, not recruiting Not applicable Interventional

Home Based Tele-exercise for People With Chronic Neurological Impairments

NCT04564495
View directory record Official record
Conditions
Neurologic Disorder, Stroke, Spinal Cord Injuries, Cerebral Palsy, Hemiplegia, Hemiparesis, Multiple Sclerosis, Parkinson Disease, Trauma, Brain, Transverse Myelitis, Friedreich Ataxia
Interventions
Seated exercise
Behavioral
Lead sponsor
Burke Medical Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 22, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Multimodal Exercise Training Poststroke

NCT03174392
View directory record Official record
Conditions
Exercise, Stroke
Interventions
Resistance Based Training, Speed Based Training
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 22, 2026, 4:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neuroplasticity in Parkinson's Disease

NCT05286736
View directory record Official record
Conditions
Parkinson, Parkinson Disease
Interventions
Neuroimaging, Quantitative assessments
Diagnostic Test
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 22, 2026, 4:26 AM EDT
Completed No phase listed Observational

Rest Before Physical Therapy in Adolescents With Active Spondylolysis and Spondylolisthesis

NCT02332200
View directory record Official record
Conditions
Spondylolysis, Spondylolisthesis, Low Back Pain
Interventions
Physical Therapy
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
4
States / cities
Columbus, Ohio • Dublin, Ohio • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Oct 22, 2026, 4:26 AM EDT
Completed Not applicable Interventional

Analysis of Brain Activity to Uncover Brain-behavior Relationships Related to Therapy Outcomes in Aphasia

NCT03550092
View directory record Official record
Conditions
Aphasia
Interventions
Abstract Semantic Association Network Training (AbSANT)
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
Not listed
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 22, 2026, 4:26 AM EDT