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Showing 1–5 of 5 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Restylane Defyne Clear all
Completed Not applicable Interventional Results available

Restylane Defyne in a Stepwise Treatment Approach

NCT04520997
View directory record Official record
Conditions
Lower Face Folds and Lines
Interventions
Restylane Defyne
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Birmingham, Alabama • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Evaluate the Safety and Effectiveness Assessments of Restylane-Defyne for Punctual Occlusion

NCT04022382
View directory record Official record
Conditions
Dry Eye
Interventions
Restylane Defyne
Device
Lead sponsor
John C Meyer, MD
Other
Eligibility
21 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Sep 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Perioral Rejuvenation and Upper Lip Enhancement

NCT03273543
View directory record Official record
Conditions
Perioral Rejuvenation, Upper Lip Projection
Interventions
Restylane® Defyne
Device
Lead sponsor
DeNova Research
Other
Eligibility
21 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Sep 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Safety and Efficacy of Restylane Defyne for Chin Augmentation and Correction of Chin Retrusion

NCT03624816
View directory record Official record
Conditions
Chin Retrusion, Chin Augmentation
Interventions
Restylane Defyne
Device
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
11
States / cities
Los Angeles, California • Manhattan Beach, California • Redondo Beach, California + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 2, 2026, 7:02 AM EDT
Completed Not applicable Interventional

A Study to Evaluate the Safety and Effectiveness of Restylane-Defyne for Punctual Occlusion

NCT03709641
View directory record Official record
Conditions
Mild to Moderate Dry Eye Disease
Interventions
Restylane Defyne
Device
Lead sponsor
John C Meyer, MD
Other
Eligibility
21 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 9, 2018 · Synced Sep 2, 2026, 7:02 AM EDT