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ClinicalTrials.gov public records Last synced Sep 27, 2026, 8:38 AM EDT

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Showing 1–24 of 70 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Reverse Shoulder Arthroplasty Clear all
Recruiting Phase 4 Interventional

Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement

NCT06143306
View directory record Official record
Conditions
Total Shoulder Arthroplasty
Interventions
bupivacaine., Saline
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Sep 27, 2026, 8:38 AM EDT
Terminated Not applicable Interventional

Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures

NCT02597972
View directory record Official record
Conditions
Closed Fracture Proximal Humerus, Four Part
Interventions
Fracture repair, Fracture repair with joint replacement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
70 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Sep 27, 2026, 8:38 AM EDT
Active, not recruiting Not applicable Interventional

Post-Market Study of Comprehensive Reverse Augmented Glenoid and Mini Humeral Tray in Total Shoulder Arthroplasty

NCT03726554
View directory record Official record
Conditions
Arthropathy of Shoulder Region, Grossly Deficient Rotator Cuff, Osteoarthritis of the Shoulder, Rheumatoid Arthritis Without Humeral Metaphyseal Defects, Post-Traumatic Arthritis
Interventions
Comprehensive Reverse Porous Augmented Glenoid, Comprehensive Mini Humeral Tray
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2030
U.S. locations
6
States / cities
Gulf Breeze, Florida • Louisville, Kentucky • Royal Oak, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 27, 2026, 8:38 AM EDT
Recruiting No phase listed Observational

AETOS Shoulder System

NCT06319911
View directory record Official record
Conditions
Shoulder Osteoarthritis, Shoulder Arthritis
Interventions
AETOS
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
5
States / cities
San Francisco, California • Denver, Colorado • Columbus, Georgia + 2 more
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Sep 27, 2026, 8:38 AM EDT
Completed No phase listed Observational

Reverse Shoulder Replacement: Age 60 or Younger Outcomes

NCT03148184
View directory record Official record
Conditions
Shoulder Arthritis
Interventions
shoulder x-ray
Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Sep 27, 2026, 8:38 AM EDT
Withdrawn Not applicable Interventional

Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis

NCT06513559
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Anatomic total shoulder replacement, Reverse total shoulder replacement
Device
Lead sponsor
University of Utah
Other
Eligibility
60 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Sep 27, 2026, 8:38 AM EDT
Completed No phase listed Observational Results available

Prediction of Development of Scapular Notching Following Reverse Total Shoulder Arthroplasty

NCT02052466
View directory record Official record
Conditions
Osteoarthritis, Rotator Cuff Tear Arthropathy, Reverse Total Shoulder Arthroplasty, Scapular Notching
Interventions
Not listed
Lead sponsor
Eric Ricchetti
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Sep 27, 2026, 8:38 AM EDT
Terminated Not applicable Interventional Results available

Total vs. Reverse Shoulder Replacement: Pain Relief Two Years After Surgery

NCT01884077
View directory record Official record
Conditions
Arthritis
Interventions
Reverse Shoulder Arthroplasty, Total Shoulder Arthroplasty
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
70 Years to 95 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Sep 27, 2026, 8:38 AM EDT
Enrolling by invitation Not applicable Interventional

The Influence of Repairing the Sub-scapularis on Outcomes After Reverse Arthroplasty

NCT03711175
View directory record Official record
Conditions
Severe Arthropathy With a Grossly Deficient Rotator Cuff
Interventions
Subscapularis repair, Shoulder implant
Procedure · Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
4
States / cities
St Louis, Missouri • New York, New York • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Sep 27, 2026, 8:38 AM EDT
Recruiting Not applicable Interventional

A Study Comparing Shoulder Replacement Techniques For Patients With Shoulder Arthritis And An Intact Rotator Cuff

NCT07584356
View directory record Official record
Conditions
Shoulder Arthritis
Interventions
aTSA, rTSA
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
60 Years to 85 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 27, 2026, 8:38 AM EDT
Recruiting Not applicable Interventional

Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty

NCT06831422
View directory record Official record
Conditions
Shoulder Arthroplasty, Positive C. Acnes Culture
Interventions
Povidone-Iodine, Hydrogen Peroxide, Xperience Antimicrobial Wash, Bacterial Cultures, Shoulder Arthroplasty
Device · Diagnostic Test · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 27, 2026, 8:38 AM EDT
Active, not recruiting No phase listed Observational

Perform® Humeral System - Fracture Study (PFX)

NCT05773352
View directory record Official record
Conditions
Traumatic Arthropathy of Shoulder, Fracture Humerus, Traumatic Arthritis, Revision of Other Devices if Sufficient Bone Stock Remains
Interventions
Tornier Perform® Humeral System - Fracture
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2034
U.S. locations
9
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Rancho Mirage, California + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 27, 2026, 8:38 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Abduction Brace Versus Antirotation Sling for Immobilization Following Reverse Shoulder Arthroplasty and Rotator Cuff Repair

NCT03488433
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
Interventions
Abduction brace, Antirotation sling
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Sep 27, 2026, 8:38 AM EDT
Enrolling by invitation No phase listed Observational

Reverse Shoulder Arthroplasty vs Rotator Cuff Repair for 60+

NCT06848023
View directory record Official record
Conditions
Shoulder Injuries, Shoulder Pain
Interventions
Reverse Total Shoulder Arthroplasty, Rotator Cuff Repair
Procedure
Lead sponsor
Campbell Clinic
Other
Eligibility
60 Years to 95 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Germantown, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 27, 2026, 8:38 AM EDT
Recruiting Not applicable Interventional

Subscapularis Repair Augmentation for Total Shoulder Arthroplasty

NCT05487677
View directory record Official record
Conditions
Shoulder Injuries
Interventions
BioBrace Augmentation, Standard Repair with Sutures
Device · Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 27, 2026, 8:38 AM EDT
Withdrawn Not applicable Interventional

Effect of Postop Rehab Methods on Outcomes Following Reverse Shoulder Arthroplasty

NCT04285606
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Shoulder Osteoarthritis
Interventions
Patient-led rehab with short immobilization
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Sep 27, 2026, 8:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prospective Low Dose CT for Total Shoulder Arthroplasty/Reverse Shoulder Arthroplasty

NCT05350319
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
A low-dose CT scan of the shoulder
Radiation
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 13, 2023 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Not applicable Interventional

Physical Therapy After Reverse Total Shoulder Arthroplasty

NCT03547726
View directory record Official record
Conditions
Orthopedic Disorder
Interventions
Physical Therapy, Self-Rehab
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 31, 2022 · Synced Sep 27, 2026, 8:38 AM EDT
Withdrawn Phase 3 Interventional

Multimodal Analgesia in Shoulder Arthroplasty

NCT03586934
View directory record Official record
Conditions
Shoulder Pain, Opioid Use
Interventions
Acetaminophen, Celecoxib 200mg, Celecoxib 400 mg, Ropivacaine, Ketorolac, Acetaminophen Injectable Product, Oxycodone, Tramadol, Morphine Injectable Solution, hydrocodone bitartrate and acetaminophen, Morphine, Oxycodone Hydrochloride, Meloxicam
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Sep 27, 2026, 8:38 AM EDT
Recruiting No phase listed Observational

FX Shoulder Solutions Retrospective / Prospective Clinical Study

NCT06077942
View directory record Official record
Conditions
Rotator Cuff Syndrome of Shoulder and Allied Disorders, Osteoarthritis Shoulder, Fracture, Shoulder
Interventions
FX Artificial Shoulder Prosthesis
Device
Lead sponsor
FX Shoulder Solutions
Industry
Eligibility
Not listed
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
2
States / cities
Gilbert, Arizona • The Villages, Florida
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 27, 2026, 8:38 AM EDT
Recruiting Not applicable Interventional

Prophylactic Conjoint Tendon Lengthening During Reverse Shoulder Arthroplasty Outcomes

NCT06729983
View directory record Official record
Conditions
Osteoarthritis Shoulder
Interventions
Prophylactic Conjoint Tendon Lengthening, Standard Reverse Shoulder Arthroplasty
Procedure
Lead sponsor
Nickolas Garbis
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Sep 27, 2026, 8:38 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Reverse Total Shoulder Arthroplasty: A Data Analysis on Patients Undergoing Reverse Total Shoulder Arthroplasty

NCT03617107
View directory record Official record
Conditions
Osteo Arthritis Shoulders, Proximal Humeral Fracture, Rotator Cuff Tear, Rotator Cuff Tear Arthropathy
Interventions
reverse total shoulder arthroplasty
Other
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Sep 27, 2026, 8:38 AM EDT
Terminated No phase listed Observational Results available

A Post-Market Clinical Evaluation of the ReUnion Reverse Shoulder Arthroplasty (RSA) System

NCT03880955
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
ReUnion RSA System
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years to 99 Years
Enrollment
102 participants
Timeline
2019 – 2023
U.S. locations
3
States / cities
Peoria, Illinois • Greenville, South Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Sep 27, 2026, 8:38 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Liposomal Bupivacaine Versus Interscalene Nerve Block

NCT03929146
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Exparel, Interscalene Nerve Block
Drug · Procedure
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Sep 27, 2026, 8:38 AM EDT