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Conditions: Obesity, Adolescent, Health Behavior, Health Knowledge, Attitudes, Practice, Diet, Healthy, Exercise, Health Literacy
Interventions: Obesity Prevention, Health Literacy; Behavioral
Lead sponsor: City University of New York, School of Public Health; Other
Eligibility: 13 Years to 17 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: PTSD, Alcohol Abuse, Alcohol Dependence
Interventions: Cognitive Processing Therapy (CPT), Relapse Prevention (RP); Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 2
States / cities: Seattle, Washington

Conditions: Suicide Risk
Interventions: TIPS Program, TIPS Program + ED-SAFE; Other
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 32,406 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: HIV, Men
Interventions: Intervention-Passport and Peer Mentor, Control-Passport Only; Behavioral
Lead sponsor: Charles Drew University of Medicine and Science; Other
Eligibility: 18 Years and older · Male only
Enrollment: 105 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: Los Angeles, California

Conditions: Diet, Food and Nutrition, Accidental Falls, Cardiovascular Diseases, Diabetes, Debility, Frailty, Functional Disability
Interventions: Meals + RD services, Meals + OT services, Meals + RD + OT services; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 60 Years and older
Enrollment: 750 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: COVID-19
Interventions: COVID-19 Group Problem Solving, Standard of Care, Booster session; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 359 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Depression, Major Depressive Disorder, Dysthymic Disorder, Depressive Symptoms, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Stroke
Interventions: Beating the Blues (BtB), Problem Solving Treatment in Primary Care (PST-PC), Antidepressant Medications, Usual Care; Behavioral · Drug · Other
Lead sponsor: Indiana University; Other
Eligibility: 50 Years and older
Enrollment: 216 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: COVID-19, Long Haul
Interventions: Ritonavir-Boosted Nirmatrelvir (Paxlovid), Physiological Evaluation, Moderna COVID-19 Vaccine, Biopsychological, Behavioral (e.g., Psychotherapy, Lifestyle Counseling), Genetic (including gene transfer, stem cell and recombinant DNA), Multidisciplinary approach; Drug · Diagnostic Test · Biological + 3 more
Lead sponsor: Well- Konnect Healthcare Services and Research Firm; Network
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2030
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Tobacco Abuse, Alcohol Abuse, Drug Abuse
Interventions: Computer Screening, Brief Intervention, Referral toTreatment; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sexual Behavior, Alcohol Consumption, Sexually Transmitted Diseases
Interventions: Knowledge alone, Self-efficacy alone, Perceived benefits alone, Perceived benefits and self-efficacy, Injunctive norms, Injunctive norms and self-efficacy, Injunctive norms and perceived benefits, Injunctive norms, perceived benefits, and self-efficacy, Descriptive norms alone, Descriptive norms and self-efficacy, Descriptive norms and perceived benefits, Descriptive norms,perceived benefits,self-efficacy, Descriptive and injunctive norms, Descriptive norms, injunctive norms,self-efficacy, Descriptive and injunctive norms, benefits, Descriptive and injunctive norms, benefits,efficacy, Expectancies alone, Expectancies and self-efficacy, Expectancies and Perceived Benefits, Expectancies, perceived benefits, self-efficacy, Expectancies and injunctive norms, Expectancies, injunctive norms, and self-efficacy, Expectancies, injunctive norms, benefits, Expectancies, injunctive norms, benefits, efficacy, Expectancies and descriptive norms, Expectancies, descriptive norms, and self-efficacy, Expectancies, descriptive norms, and benefits, Expectancies,descriptive norms, benefits, efficacy, Expectancies, descriptive and injunctive norms, Expectancies, descr& injun norms, efficacy, Expectancies, desc & injun norms, benefits, Expectancies,desc & injun norms,benefits,efficacy; Behavioral
Lead sponsor: Penn State University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 3,997 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 4
States / cities: Fresno, California • Carbondale, Illinois • Greensboro, North Carolina + 1 more

Conditions: Suicide Prevention
Interventions: Practice Facilitation, Training in National Institute of Mental Health Youth Suicide Prevention Pathway; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 12 Years to 80 Years
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: HIV
Interventions: Lenacapavir long-acting, Standard of Care (SOC); Drug · Other
Lead sponsor: Kelley-Ross & Associates, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: COVID-19
Interventions: COVID-19 Group Problem Solving, Standard of Care, Booster session; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Depression, Anxiety, Suicide, Drug Use
Interventions: eHealth Familias Unidas Mental Health; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Years to 16 Years
Enrollment: 468 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2028
U.S. locations: 17
States / cities: Miami, Florida

Conditions: Risk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
Interventions: CHRP-BB; Other
Lead sponsor: University of Connecticut; Other
Eligibility: 18 Years and older
Enrollment: 237 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
Interventions: Project Legacy; Behavioral
Lead sponsor: Children's Hospital Los Angeles; Other
Eligibility: 14 Years to 19 Years
Enrollment: 571 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 12
States / cities: Boyle Heights, California • Long Beach, California • Los Angeles, California + 3 more

Conditions: Opioid Overdose Prevention, People Who Use Opioids/People With Opioid Use Disorder (OUD), Reduction of Substance Use-related Stigma, Non-substance-using People With a Friend or Family Member Who Uses Opioids, Peer Harm Reduction Support Champions
Interventions: Peer Harm Reduction Support Champion Intervention; Behavioral
Lead sponsor: University of Illinois at Chicago; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Breast Cancer Screening, Breast Carcinoma in Situ, Breast Cancer
Interventions: Complete a health questionnaire, Provide a saliva sample for genetic testing, Screening advice based on a comprehensive risk assessment, Screening advice based on a basic risk assessment; Other · Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 30 Years to 74 Years · Female only
Enrollment: 100,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2029
U.S. locations: 11
States / cities: Birmingham, Alabama • Irvine, California • Los Angeles, California + 8 more

Conditions: Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetic State &Amp; High Risk Individuals on the Basis of Diabetes Risk Score
Interventions: Linkage to Care, Educational, Healthy Lifestyle Tools; Behavioral · Other
Lead sponsor: Xavier University of Louisiana.; Other
Eligibility: 18 Years to 99 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Substance Related Disorders
Interventions: Just Care for Families (JCFF), Just Care for Families (JCFF) App, Just Care for Families (JCFF) App Feedback; Behavioral
Lead sponsor: Chestnut Health Systems; Other
Eligibility: Not listed
Enrollment: 254 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Sudden Infant Death
Interventions: Safety Baby shower, Standard of Care; Behavioral
Lead sponsor: Arkansas Children's Hospital Research Institute; Other
Eligibility: 13 Years to 19 Years · Female only
Enrollment: 146 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Dementia, Postoperative Delirium (POD), Postoperative Neurocognitive Disorder, Major Adverse Cardiac and Cerebrovascular Events, Perioperative Complications, Postoperative Cognitive Decline
Interventions: Personalized CPC Prehabilitation, Cognitive Training, Meditation, Daily Exercise, Enhanced Social Support, Proactive Bundle Interventions, Pre-operative Standard of Care, Intra-operative Standard of Care; Other · Behavioral · Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 65 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 5
States / cities: Pittsburgh, Pennsylvania

Conditions: Diabetes, Chronic Disease, Psychological Distress
Interventions: Immediate Chronic Disease Prevention Program (CDPP), Workplace Equity, Job and Health Supports Employer Intervention, Delayed, attenuated Chronic Disease Prevention Program (CDPP); Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 64 Years
Enrollment: 455 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Substance Use
Interventions: Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI), Standard Referral to Treatment (RT), Family Screening, Family Psychoeducation, Family Brief Negotiated Interview (BNI), Family Facilitated Conversation (FC) & Referral to Treatment (RT); Behavioral
Lead sponsor: The National Center on Addiction and Substance Abuse at Columbia University; Other
Eligibility: 12 Years to 17 Years
Enrollment: 2,300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: New York, New York

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Health Literacy and Obesogenic Behaviors

Sequence of Symptom Change During AUD or PTSD Treatment for Comorbid PTSD/AUD

Telehealth to Improve Prevention of Suicide (TIPS)

Reducing HIV Risk With High Risk HIV Negative Black MSM-Passport to Wellness

Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

Vale+Tú Salud: Corner-Based Randomized Trial to Test a Latino Day Laborer Program Adapted to Prevent COVID-19

eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients

Covid-19 Long Haul Preventative and Health Promotion Care Clinical Trial Acceleration Program.

cSBIRT to Reduce Teen Tobacco, Alcohol and Drug Use

Engineering an Online STI Prevention Program

Practice Facilitation to Enhance Implementation of a Pediatric Suicide Prevention Pathway

Implementation and Deliver of Lenacapavir for PrEP in a Community Pharmacy Setting

Vale+Tú Salud: Corner-Based Trial to Test a Latino Day Laborer Program Adapted to Prevent COVID-19

Mental Health in Primary Care

Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs

Project Legacy Impact Evaluation Study

Reducing Overdose and Substance Use-related Stigma by Training Non-substance-using Friends and Family Members of People Who Use Opioids to Be Harm Reduction Champions

Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

Pharmacists' Delivery of Education to Prevent Diabetes in the New Orleans Hospitality Industry

Testing Implementation Strategies to Scale-up a Multicomponent Continuum of Service Intervention for Families Involved in Systems With Parental Opioid and Methamphetamine Use

Generations in Families Talking Safe Sleep

Prediction and Prevention of Postoperative Mortality and Morbidity

NC Works4Health: Reducing Chronic Disease Risks in Socioeconomically Disadvantaged, Unemployed Populations

Primary Connections for Youth and Families