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ClinicalTrials.gov public records Last synced Oct 11, 2026, 8:41 AM EDT

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Showing 73–96 of 141 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Ropivacaine 0.2% Clear all
Completed Not applicable Interventional

Ultrasound-Guided Block of the Lateral Femoral Cutaneous Nerve in Pediatric Patients

NCT01500655
View directory record Official record
Conditions
Burns
Interventions
Regional nerve block, Catheter
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
2 Years to 21 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Pudendal Nerve Block and Caudal Block for Hypospadias in Young Children

NCT03145415
View directory record Official record
Conditions
Hypospadias and Epispadias
Interventions
Caudal block, Bilateral Pudendal block
Procedure
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Months to 2 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 11, 2026, 8:41 AM EDT
Withdrawn Phase 4 Interventional

Adductor Canal Catheter vs Local Infiltration of Analgesia for Total Knee Arthroplasty

NCT02603900
View directory record Official record
Conditions
Acute Pain, Regional Anesthesia Morbidity
Interventions
ropivacaine, bupivacaine, Sham Adductor Canal Catheter, Adductor Canal Catheter
Drug · Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
40 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 11, 2026, 8:41 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Continuous Erector Spinae Block Versus Continuous Paravertebral Block

NCT03768440
View directory record Official record
Conditions
Pain, Postoperative
Interventions
continuous erector spinae block (ESB), continuous paravertebral block (PVB), Ropivacaine
Procedure · Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Month to 12 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Phase 4 Interventional Results available

Transverse Abdominis Plane (TAP) Block After Cesarean Delivery

NCT01170702
View directory record Official record
Conditions
Postoperative Pain, Pregnancy, Obesity
Interventions
0.9% Normal Saline, 0.2% Ropivacaine, 0.5% Ropivacaine, 0.75% Ropivacaine
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 8, 2021 · Synced Oct 11, 2026, 8:41 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Quadratus Lumborum vs Erector Spinae Supplementary Blocks With Lumbar Plexus Blocks for Hip PAO

NCT04481451
View directory record Official record
Conditions
Pain, Postoperative, Regional Anesthesia, Hip Dysplasia
Interventions
Erector spinae block with ropivacaine 0.2%, Quadratus lumborum block with ropivacaine 0.2%, Ropivacaine
Procedure · Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
15 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery

NCT01167907
View directory record Official record
Conditions
Orthopedic Surgery of Lower Extremity
Interventions
0.2% ropivacaine, saline
Device · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 11, 2026, 8:41 AM EDT
Recruiting Phase 1Phase 2 Interventional

Minimally Invasive Esophagectomy Pain Control Trial

NCT05906134
View directory record Official record
Conditions
Postoperative Pain, Acute, Postoperative Complications
Interventions
Local intercostal nerve block, Cryo-analgesia and intercostal nerve block, Serratus plane catheter blocks and intercostal nerve blocks, Thoracic epidural catheter
Procedure
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Oct 11, 2026, 8:41 AM EDT
Recruiting Phase 4 Interventional

Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture

NCT06278987
View directory record Official record
Conditions
Hip Fractures
Interventions
PENG block and cryoablation, fascia iliaca compartment block
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Not applicable Interventional Results available

Liposomal Bupivacaine Versus Standard of Care in Total Knee Surgery

NCT02219087
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Liposomal bupivacaine, Standard of Care
Drug
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Oct 11, 2026, 8:41 AM EDT
Terminated Phase 4 Interventional Results available

Paravertebral Nerve Blocks in Neonates

NCT03408340
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Paravertebral Nerve Block, Standard of Care Anesthesia
Procedure · Drug
Lead sponsor
Emory University
Other
Eligibility
Up to 12 Months
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 11, 2026, 8:41 AM EDT
Recruiting Phase 4 Interventional

INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures

NCT05642026
View directory record Official record
Conditions
Rib Fractures
Interventions
Ropivacaine, Non steroidal anti-inflammatory drug and opioids
Drug
Lead sponsor
Zachary Warriner
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Phase 4 Interventional Results available

Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty

NCT01759277
View directory record Official record
Conditions
Postoperative Pain Following Knee Arthroplasty
Interventions
Control: Femoral perineural local anesthetic infusion, Experimental: Adductor Canal perineural local anesthetic infusion
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2021 · Synced Oct 11, 2026, 8:41 AM EDT
Terminated Phase 4 Interventional Results available

Low Dose IV Dexamethasone in Prolonging Caudal Anesthesia in Children Undergoing Genitourinary Surgery

NCT02436265
View directory record Official record
Conditions
Surgery
Interventions
Dexamethasone, Ropivacaine
Drug
Lead sponsor
Indiana University
Other
Eligibility
2 Years to 10 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Suprazygomatic Maxillary Nerve Block in Cleft Palate Outcomes

NCT04909619
View directory record Official record
Conditions
Cleft Palate Children
Interventions
Ultrasound-guided bilateral suprazygomatic maxillary nerve block, Local anesthetic infiltration of the palate
Procedure
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
9 Months to 2 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)

NCT02223364
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Peripheral nerve blocks with Bupivacaine, Intra articular injection with Ropivacaine, Intra articular injection with liposomal bupivacaine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular

NCT02242201
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
PNB Bupivacaine, PAI Ropivacaine, PAI liposomal bupivacaine, Epinephrine, Ketorolac
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 19, 2018 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Not applicable Interventional

Randomized Study of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery

NCT07052721
View directory record Official record
Conditions
Rotator Cuff Tears, Shoulder Injuries, Hallux Valgus, Ankle Arthropathy, Clavicle Fracture
Interventions
Experimental Treatment, Sham Comparator
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Not applicable Interventional

Pain Control for Anterior Cruciate Ligament Reconstruction Patients With Adductor Canal or Femoral Perineural Infusions

NCT03208478
View directory record Official record
Conditions
Pain, Postoperative, Anterior Cruciate Ligament Injury
Interventions
Adductor Canal perineural catheter placement, Femoral Nerve perineural catheter placement, Nimbus pump (Infutronix)
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Phase 3 Interventional Results available

A Study to Compare the Effectiveness of Adductor Canal Pain Catheters Following Total Knee Arthroplasty

NCT05053087
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Ropivacaine Continuous Infusion, Ropivacaine Intermittent Bolus, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 11, 2026, 8:41 AM EDT
Completed Not applicable Interventional

Comparing the Efficacy of Epidural and Quadratus Lumborum Analgesia After Open Nephrectomy Surgery

NCT03110081
View directory record Official record
Conditions
Open Nephrectomy Surgery
Interventions
Quadratus lumborum block, Epidural analgesia
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
Not listed
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 11, 2026, 8:41 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Dexamethasone or Clonidine as Adjuncts to Ropivacaine for Caudal Analgesia on Analgesia Duration in Children

NCT02773602
View directory record Official record
Conditions
Postoperative Pain
Interventions
Dexamethasone, Clonidine, Normal Saline
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
6 Months to 6 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2016 · Synced Oct 11, 2026, 8:41 AM EDT
Terminated Not applicable Interventional Results available

The Effects of Dexamethasone on the Duration of Sciatic Nerve Blocks

NCT00616603
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Ropivacaine, Dexamethasone, Normal Saline
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2014 · Synced Oct 11, 2026, 8:41 AM EDT