Independent directory Public ClinicalTrials.gov records United States
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Showing 2449–2472 of 3,418 matching trials from the live ClinicalTrials.gov search.
Conditions
Spine Surgery
Interventions
Methadone-dexmedetomidine-ketamine combination
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 79 Years
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Trauma Blunt, Orthopedic
Interventions
Comprehensive trauma recovery programming (C-TRP), Standard of Care (Investigator Selected)
Behavioral · Other
Lead sponsor
Stephanie Di Stasi
Other
Eligibility
18 Years and older
Enrollment
804 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
7
States / cities
Aurora, Colorado • Baltimore, Maryland • Minneapolis, Minnesota + 3 more
Enrolling by invitation Phase 4 Interventional

Intra-Articular Catheter Total Knee Arthroplasty

NCT06580899
Conditions
Continuous Local Infiltration Analgesia, Intra-articular Catheter, Total Knee Arthroplasty
Interventions
Intra-articular catheter, Routine Standard of Care Treatment
Device · Other
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charlotte, North Carolina
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluating Image Quality and Comfort of an Investigational Curved Paddle Compared to a Standard Paddle

NCT03611543
Conditions
Breast Cancer
Interventions
Standard of Care Flat Paddle, Investigational Curved Paddle
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
25 Years and older · Female only
Enrollment
443 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
4
States / cities
Stamford, Connecticut • Rochester, New York • Addison, Texas + 1 more
Conditions
Diabetes During Pregnancy
Interventions
High-Protein Beverage (Genius Gourmet Sparkling Protein Water), Standard Clear Liquid Diet, Continuous Glucose Monitoring (Abbott Freestyle Libre)
Dietary Supplement · Other · Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Atrial Fibrillation
Interventions
High intensity interval training, Moderate intensity continuous training, No Exercise
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Interventions
Percutaneous Coronary Intervention (PCI)
Procedure
Lead sponsor
University of British Columbia
Other
Eligibility
Not listed
Enrollment
4,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
55
States / cities
Huntsville, Alabama • Phoenix, Arizona • Palo Alto, California + 49 more
Conditions
Women at Increased Risk for Developing Breast Carcinoma
Interventions
Mammography (CESM) and MRI
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
21 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
New York, New York
Conditions
Patients Implanted With Monofocal Intraocular Lens
Interventions
Monofocal Intraocular Lenses
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Williamsburg, Virginia
Conditions
Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS), Subclinical Cushing's, Mild Autonomous Cortisol Excess
Interventions
Intervention 1: Adrenalectomy, Intervention 2: Semaglutide
Procedure · Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Traumatic Brain Injury (TBI) Patients
Interventions
Walking
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
East Hanover, New Jersey
Completed Not applicable Interventional Results available

Ultrasound Assisted Lumbar Puncture in the Neonate

NCT02918149
Conditions
Lumbar Puncture
Interventions
Palpation Landmark Technique, Ultrasound-Assisted Technique LP
Other · Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 6 Months
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Rotator Cuff Tear Surgical Repair
Interventions
Routine post-surgical care plus H-Wave® Device Stimulation (HWDS), Routine post-surgical care
Device · Other
Lead sponsor
Electronic Waveform Lab
Industry
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Overland Park, Kansas • Kansas City, Missouri • Lee's Summit, Missouri + 1 more
Conditions
Gestational Diabetes, Maternal Complication of Pregnancy
Interventions
Continuous Glucose Monitor, Routine Care
Device · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Tai ji Quan Exercise to Prevent Falls in Older Adults

NCT05822466
Conditions
Accidental Fall
Interventions
Virtual tai ji quan: moving for better balance intervention (V-TJQMBB), Virtual multimodal exercise intervention (V-Multimodal)
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
65 Years to 90 Years
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Springfield, Oregon
Completed Not applicable Interventional Results available

Home Telemonitoring In Patients After Myocardial Infarction

NCT04664881
Conditions
Myocardial Infarction, Heart Attack
Interventions
SmartHeart Device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Cystoscopy
Interventions
furosemide, Normal Saline
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Hypertension, Type 2 Diabetes
Interventions
Home visit
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Obesity
Interventions
Small Changes program, Standard behavioral therapy for weight loss
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Houston, Texas • Lubbock, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Young Men's Health Project Targeting HIV Risk Reduction and Substance Abuse

NCT03577301
Conditions
HIV Infections
Interventions
Clinic-based Delivery, Remote Delivery, Multi-modal Delivery
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
Miami, Florida • Detroit, Michigan • Philadelphia, Pennsylvania
Conditions
Bleeding Disorders, Iron, Platelet, Bleeding
Interventions
IV Iron (standard of care)
Drug
Lead sponsor
Nicoletta C Machin
Other
Eligibility
15 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Breast Cancer
Interventions
hCG
Drug
Lead sponsor
New York Presbyterian Hospital
Other
Eligibility
30 Years to 75 Years · Female only
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Conditions
Blood Pressure
Interventions
Caretaker
Device
Lead sponsor
Cooper Norcross Health
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Camden, New Jersey
Conditions
Sinus Node Dysfunction
Interventions
Treadmill/Bicycle exercise testing
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York