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ClinicalTrials.gov public records Last synced Oct 5, 2026, 4:40 PM EDT

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Showing 49–72 of 261 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Roux-En-Y Gastric Bypass Clear all
Completed No phase listed Observational

Laparoscopic Revision of Vertical Banded Gastroplasty to Gastric Bypass

NCT01041131
View directory record Official record
Conditions
Clinically Severe Obesity, Inadequate Weight Loss, Obesity Recidivism
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Jan 1, 2010 · Synced Oct 5, 2026, 4:40 PM EDT
Recruiting Not applicable Interventional

Truncal Vagotomy in Patients Undergoing Revisional Sleeve Gastrectomy to Gastric Bypass

NCT04901429
View directory record Official record
Conditions
GERD
Interventions
Truncal vagotomy
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 5, 2026, 4:40 PM EDT
Recruiting Not applicable Interventional

Autonomic Neural Blockade in Bariatric Surgery

NCT07104825
View directory record Official record
Conditions
Bariatric Surgery Candidate, Pain, Postoperative, Nausea and Vomiting, Postoperative, Opioid Use
Interventions
Intraoperative autonomic neural blockade (ANB), Laparoscopic Standard of Care Abdominal Wall Block
Procedure
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 90 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 5, 2026, 4:40 PM EDT
Terminated Not applicable Interventional

Total Joint Arthroplasty (TJA) Weight Loss Study

NCT05156762
View directory record Official record
Conditions
Osteoarthritis, Hip, Osteoarthritis, Knee, Obesity, Morbid
Interventions
Bariatric surgery, Medical weight loss, Patient research surveys, Total joint arthroplasty (TJA), Usual standard of care
Procedure · Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 5, 2026, 4:40 PM EDT
Completed No phase listed Observational

Metabolomics of Roux-en-Y Gastric Bypass (RYGB) With Gastrostomy

NCT00887302
View directory record Official record
Conditions
Type II Diabetes Mellitus, Obesity
Interventions
Gastric Band, Gastric Sleeve, Gastrostomy Tube
Procedure
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 6, 2023 · Synced Oct 5, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Advanced Medical Therapy Versus Advanced Medical Therapy Plus Bariatric Surgery for the Resolution of Type 2 Diabetes

NCT00432809
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Gastric bypass, Sleeve Gastrectomy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
20 Years to 60 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Oct 5, 2026, 4:40 PM EDT
Withdrawn Not applicable Interventional

Sleeve Gastrectomy Versus Gastric Bypass for Private Pay Patients Seeking Obesity Surgery

NCT01063959
View directory record Official record
Conditions
Morbid Obesity
Interventions
Laparoscopic Sleeve Gastrectomy, Laparoscopic Gastric Bypass
Procedure
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 18, 2015 · Synced Oct 5, 2026, 4:40 PM EDT
Completed No phase listed Observational

Bone Metabolism After Bariatric Surgery

NCT01824797
View directory record Official record
Conditions
Obesity, Osteoporosis
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
40 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2019 · Synced Oct 5, 2026, 4:40 PM EDT
Not listed Phase 3 Interventional

Randomized Controlled Trial of Laparoscopic Gastric Bypass Plus Omentectomy Versus Laparoscopic Gastric Bypass Alone in Improving Diabetic Indices

NCT00552942
View directory record Official record
Conditions
Diabetes, Interleukins, Cytokines
Interventions
laparoscopic gastric bypass plus omentectomy
Procedure
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 2, 2007 · Synced Oct 5, 2026, 4:40 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Mechanisms of Post-Bariatric Hypoglycemia

NCT04428866
View directory record Official record
Conditions
Hypoglycemia
Interventions
Continuous Glucose Monitoring, activity monitor, Mixed meal tolerance test, Glucagon Sensitivity Testing, Hypoglycemic Hyperinsulinemic Clamp, analysis of fecal microbiome
Diagnostic Test
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 70 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2024 · Synced Oct 5, 2026, 4:40 PM EDT
Completed No phase listed Observational

Adolescent Gastric By-pass and Diabetic Precursors

NCT00360373
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
15 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2014 · Synced Oct 5, 2026, 4:40 PM EDT
Not listed No phase listed Observational

Endoscopic Sutures For Gastrointestinal Tract Disorders: A Prospective Multicenter Registry

NCT02166125
View directory record Official record
Conditions
Endoscopic Suturing Within the Gastrointestinal Tract
Interventions
Endosuturing
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
3
States / cities
Kenner, Louisiana • New York, New York • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 20, 2017 · Synced Oct 5, 2026, 4:40 PM EDT
Completed No phase listed Observational

Wound Repair and Body Contouring Surgery After Gastric Bypass

NCT00609037
View directory record Official record
Conditions
Obesity, Morbid
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Oct 5, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Ultraviolet Light And Vitamin D In Subjects With Fat Malabsorption Or After Gastric Bypass Surgery

NCT01910792
View directory record Official record
Conditions
Vitamin D Deficiency, Gastrointestinal Diseases
Interventions
Sperti Lamp
Device
Lead sponsor
Boston University
Other
Eligibility
18 Years to 64 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 5, 2026, 4:40 PM EDT
Completed Not applicable Interventional

Post-Gastric Bypass Hypoglycemia

NCT01933490
View directory record Official record
Conditions
Hyperinsulinemic Hypoglycemia
Interventions
high carbohydrate test meal, high carbohydrate test meal after pre-treatment with rapid acting aspart insulin, high fructose , low glucose test meal with carbohydrate and caloric content similar to the control meal
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 5, 2026, 4:40 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Effect of Bariatric Surgery on Metabolism, the Metabolome and Microbiome in Patients With Type 2 Diabetes

NCT02762708
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Roux-en-Y Gastric Bypass (RYGB), Caloric Restriction, Exendin-9,39, Normal Saline
Procedure · Behavioral · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Oct 5, 2026, 4:40 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

SH Dr. Chen Gastric Bypass Study

NCT05357443
View directory record Official record
Conditions
Gastric Bypass
Interventions
Gastric bypass with transection of vagal nerves, Gastric bypass without transection of vagal nerves
Procedure
Lead sponsor
Sanford Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 5, 2026, 4:40 PM EDT
Terminated Not applicable Interventional

Bariatric Surgery for ESRD Patients vs Control

NCT00580762
View directory record Official record
Conditions
Obesity, ESRD
Interventions
Roux-en-y gastric bypass (RYGB)
Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Oct 5, 2026, 4:40 PM EDT
Active, not recruiting No phase listed Observational

Transoral Fundoplication Prior to Sleeve Gastrectomy Versus RNY Gastric Bypass on GERD Symptoms in Bariatric Patients

NCT05365087
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
Transoral Fundoplication and Sleeve Gastrectomy, Gastric Bypass
Procedure
Lead sponsor
Lexington Health Incorporated
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2032
U.S. locations
1
States / cities
West Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 5, 2026, 4:40 PM EDT
Completed No phase listed Observational

Small Bowel Length and Bariatric Surgery Outcomes

NCT02872493
View directory record Official record
Conditions
Malnutrition, Obesity, Weight Loss, Micronutrient Deficiency
Interventions
Small bowel length measurement
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 5, 2026, 4:40 PM EDT
Completed Phase 1Phase 2 Interventional

Does Weight Loss Surgery and Probiotic Supplementation Lead to a "Lean" Gut Microbiota?

NCT01870544
View directory record Official record
Conditions
Obesity
Interventions
Lactobacillus Rhamnosus GG, Placebo
Dietary Supplement
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 10, 2016 · Synced Oct 5, 2026, 4:40 PM EDT
Completed Not applicable Interventional Results available

Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes

NCT01073020
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Allergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group
Device · Other · Procedure
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Oct 5, 2026, 4:40 PM EDT
Not listed Not applicable Interventional

Roux-en-Y-Gastric Bypass vs. Lifestyle Modification and Medical Therapy in the Treatment of Type 2 Diabetes

NCT01231308
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y-Gastric Bypass, Intensive lifestyle modification and Optimal medical Therapy
Procedure · Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 24, 2012 · Synced Oct 5, 2026, 4:40 PM EDT
Completed Phase 4 Interventional Results available

Pramlintide (Symlin) for the Treatment of Hypoglycemia Following Gastric Bypass Surgery

NCT01841359
View directory record Official record
Conditions
Hypoglycemia, Evidence of Previous Gastric Surgery
Interventions
Pramlintide
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2023 · Synced Oct 5, 2026, 4:40 PM EDT