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ClinicalTrials.gov public records Last synced Oct 30, 2026, 10:36 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 601–624 of 1,550 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: SAFE Clear all
Completed Not applicable Interventional

Functional Chewing Gum in Reduction of Gingival Inflammation

NCT03237624
View directory record Official record
Conditions
Gingivitis
Interventions
Functional Chitosan Chewing Gum, Control Chewing Gum, Oral hygiene measures
Device · Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 30, 2026, 10:36 AM EDT
Recruiting No phase listed Observational

Continuous Wireless Ultrasound to Monitor Fetal Health

NCT07676474
View directory record Official record
Conditions
Pregnant Woman With Single Pregnancy, Ultrasound Fetal Medicine
Interventions
Wireless Ultrasound Device
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Phase 1 Interventional

Resistance Training and Physical Functioning in Head and Neck Cancer Patients

NCT01332682
View directory record Official record
Conditions
Head and Neck Cancer, Pharyngeal Cancer, Laryngeal Cancer
Interventions
Nutrition Counseling, Resistance Training and Nutrition Counseling
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Springfield, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Not applicable Interventional Results available

Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder

NCT00539279
View directory record Official record
Conditions
Combat Disorders, Post-traumatic Stress Disorder
Interventions
Prolonged Exposure Therapy (PE), Relaxation Training (RT)
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
60 Years and older · Male only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 19, 2015 · Synced Oct 30, 2026, 10:36 AM EDT
Terminated Phase 3 Interventional Results available

Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031

NCT03573882
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Voxelotor
Drug
Lead sponsor
Pfizer
Industry
Eligibility
12 Years to 65 Years
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
34
States / cities
Little Rock, Arkansas • Oakland, California • Miami, Florida + 20 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 30, 2026, 10:36 AM EDT
Recruiting Not applicable Interventional

Using a mHealth App to Improve Quality-of-Life Outcomes in Black Prostate Cancer Survivors

NCT06651359
View directory record Official record
Conditions
Prostate Cancer
Interventions
Surveys for Quality of Life, Surveys and mHealth App access
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older · Male only
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
3
States / cities
Tallahassee, Florida • Milledgeville, Georgia • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 30, 2026, 10:36 AM EDT
Active, not recruiting Phase 2 Interventional

A Trial to Learn How the Cancer Vaccine BNT116 in Combination With Cemiplimab Works and How Safe the Combination is in Adults With Advanced Non-small Cell Lung Cancer (EMPOWERVAX Lung 1)

NCT05557591
View directory record Official record
Conditions
Advanced Non-Small Cell Lung Cancer
Interventions
BNT116, Cemiplimab
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
9
States / cities
Los Angeles, California • Santa Monica, California • Louisville, Kentucky + 6 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Phase 3 Interventional Results available

Effect of Evolocumab on Coronary Atherosclerosis

NCT03689946
View directory record Official record
Conditions
Cardiovascular Disease, Hyperlipidemia
Interventions
Evolocumab, 18F-NaF PET, CCTA, Omnipaque, Metoprolol, Nitroglycerin
Drug · Diagnostic Test
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study to Evaluate Safety, Tolerability and Preliminary Efficacy of FP-1305 in Cancer Patients (MATINS)

NCT03733990
View directory record Official record
Conditions
Cancer
Interventions
FP-1305 (bexmarilimab)
Biological
Lead sponsor
Faron Pharmaceuticals Ltd
Industry
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Not applicable Interventional Results available

A Novel Cognitive Remediation Intervention Targeting Poor Decision-making and Depression in Veterans at High Risk for Suicide: A Safe, Telehealth Approach During the COVID-19 Pandemic

NCT04952532
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Neuropsychological Educational Approach to Cognitive Remediation (NEAR, termed Cognitive Remediation plus Bridging)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 30, 2026, 10:36 AM EDT
Recruiting Phase 2 Interventional

Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab & Pertuzumab

NCT05325632
View directory record Official record
Conditions
HER2-positive Breast Cancer
Interventions
HER-2 pulsed DC1, Trastuzumab, Pertuzumab, Paclitaxel, Resection surgery
Biological · Drug · Procedure
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Phase 1 Interventional

A First-in-Human Study to Learn About How BAY3630942 is Distributed and Processed Inside the Body When Given After BAY3547922 and How Safe it is in People With Liver Cancer or Other Select Solid Cancers

NCT06345001
View directory record Official record
Conditions
Hepatocellular Carcinoma (HCC), Solid Tumors
Interventions
BAY3630942, BAY3547922
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Scottsdale, Arizona • Duarte, California • Los Angeles, California + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2025 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of Electronic Stimulation for Circumferential Reduction and Muscle Toning

NCT06152900
View directory record Official record
Conditions
Fat Necrosis, Muscle Stimulation
Interventions
Accufit
Device
Lead sponsor
CynosureLutronic
Industry
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Billerica, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 1, 2023 · Synced Oct 30, 2026, 10:36 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Tennessee Youth Prepared for Success

NCT06001892
View directory record Official record
Conditions
Adolescent Behavior, Adolescent Problem Behavior, Risk Reduction
Interventions
Tennessee Youth Prepared for Success
Behavioral
Lead sponsor
Centerstone Research Institute
Other
Eligibility
14 Years to 19 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 30, 2026, 10:36 AM EDT
Terminated Phase 1 Interventional

Next Generation Personalized Neuroblastoma Therapy

NCT02780128
View directory record Official record
Conditions
Neuroblastoma, Cancer
Interventions
Biopsy, Next Generation Sequencing, Tumor Scans, Bone marrow Tests, Physical Exam, Eye Exam, Labs, Pregnancy Test, Interviews, ECG, Echocardiogram, Ribociclib, Ceritinib
Procedure · Genetic · Other + 2 more
Lead sponsor
Yael P Mosse
Other
Eligibility
1 Year to 21 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 30, 2026, 10:36 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating Telehealth Delivery of Brief Alcohol Screening and Intervention for College Students

NCT06774300
View directory record Official record
Conditions
Alcohol Consumption
Interventions
BASICS, Online alcohol programming
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 26 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 30, 2026, 10:36 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

mHealth to Improve Diet Quality Among Early Adolescents in SNAP-Ed in Hawaii

NCT06360367
View directory record Official record
Conditions
Diet, Healthy
Interventions
HI-FLY Curriculum, HI-FLY Curriculum + PortionSize Ed app
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
11 Years to 14 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 30, 2026, 10:36 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Collaborative Approach to Examining Adversity and Building Resilience Study

NCT05259436
View directory record Official record
Conditions
Early Life Adversity, Caregiver Stress
Interventions
Caregiver-child Intervention, Enhanced Primary Care
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
4
States / cities
Oakland, California • Richmond, California • San Francisco, California + 1 more
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Not applicable Interventional

Physical Activity and Sedentary Behavior Change; Impact on Lifestyle

NCT02467881
View directory record Official record
Conditions
Sedentary Lifestyle, Physical Activity
Interventions
Physical Activity Increase (GLB-MOD), Sedentary Time Decrease (GLB-SED), 6-month delayed (DELAYED)
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
40 Years and older
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smart Parents--Safe and Healthy Kids

NCT04366687
View directory record Official record
Conditions
Child Sexual Abuse
Interventions
Smart Parents - Safe and Healthy Kids, Parents as Teachers
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
6
States / cities
Bradford, Pennsylvania • DuBois, Pennsylvania • Greensburg, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2020 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Virtual Sun Safe Workplaces Ph II (SSW Works)

NCT05774600
View directory record Official record
Conditions
Skin Cancer, Occupational Exposure
Interventions
SSW Works, Minimal Information Control
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
18 Years and older
Enrollment
543 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Golden, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 30, 2026, 10:36 AM EDT
Completed Phase 3 Interventional Results available

A Study to Find How Safe and Effective GAMMAPLEX® is in Subjects With Chronic Idiopathic Thrombocytopenic Purpura (ITP)

NCT00504075
View directory record Official record
Conditions
Chronic Idiopathic Thrombocytopenic Purpura
Interventions
Gammaplex, intravenous immunoglobulin
Biological
Lead sponsor
Bio Products Laboratory
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
7
States / cities
Orange City, Florida • Chicago, Illinois • Bethesda, Maryland + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2013 · Synced Oct 30, 2026, 10:36 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Tumescent Lidocaine Maximum Safe mg/kg Dosage

NCT00977028
View directory record Official record
Conditions
Anesthesia
Interventions
Tumescent Local Anesthesia (lidocaine, epinephrine), Liposuction
Drug · Procedure
Lead sponsor
Klein, Jeffrey A., M.D.
Individual
Eligibility
18 Years to 72 Years · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
San Juan Capistrano, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2011 · Synced Oct 30, 2026, 10:36 AM EDT
Enrolling by invitation Not applicable Interventional

Testing STAR and TextSTAR: A Randomized Controlled Trial

NCT07630428
View directory record Official record
Conditions
Sexual Violence, Posttraumatic Stress Disorder (PTSD), Opioid Misuse
Interventions
Skills Training in Active Recovery (STAR) Video, Text Skills Training in Active Recovery (TextSTAR) program
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
394 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
3
States / cities
Louisville, Kentucky • Chapel Hill, North Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 30, 2026, 10:36 AM EDT