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ClinicalTrials.gov public records Last synced Oct 22, 2026, 5:50 AM EDT

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Showing 505–528 of 8,106 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: SAMe Clear all
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Phase I Safety Trial of Streptococcus Pneumoniae Whole Cell Vaccine (SPWCV) + Alum in Healthy Adults

NCT01537185
View directory record Official record
Conditions
Pneumococcal Vaccines
Interventions
Placebo, SPWCV+Alum 100 mcg, SPWCV+Alum 600 mcg, SPWCV+Alum 300 mcg
Other · Biological
Lead sponsor
PATH Vaccine Solutions
Other
Eligibility
18 Years to 40 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jun 5, 2014 · Synced Oct 22, 2026, 5:50 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Role of Tissue Oxygenation and the miR-210 Gene In Wound Healing

NCT02024243
View directory record Official record
Conditions
Non-Diabetic Patients, Wound Leg, Chronic Ulcer Leg/Foot
Interventions
Not listed
Lead sponsor
Chandan Sen
Other
Eligibility
30 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
3
States / cities
Indianapolis, Indiana • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Oct 22, 2026, 5:50 AM EDT
Terminated Not applicable Interventional

Brain Computer Interface for Communication in Ventilated Patients

NCT02791425
View directory record Official record
Conditions
Mechanical Ventilation, Nonverbal Communication, Intratracheal Intubation, Critical Illness
Interventions
Brain Computer Interface (BCI) device, Communication picture board
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Oct 22, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Engaging College Students in Developing and Testing a Video-based Intervention for HPV Vaccination Promotion

NCT06397378
View directory record Official record
Conditions
N/A - Healthy Subjects
Interventions
short videos related to HPV and the HPV vaccine, CDC HPV Fact Sheet
Other
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 26 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 22, 2026, 5:50 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of Non-invasive Vagus Nerve Stimulation in the Treatment of Headache in Subarachnoid Hemorrhage

NCT04126408
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
gammaCore
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2024 · Synced Oct 22, 2026, 5:50 AM EDT
Completed Not applicable Interventional Results available

Identifying Ideal Reimbursement "Dose" to Reduce Clinical Trial-related Financial Toxicity

NCT05871125
View directory record Official record
Conditions
Breast Cancer
Interventions
Reimbursement
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 22, 2026, 5:50 AM EDT
Not yet recruiting Not applicable Interventional

Mechanical Ventilator Adjustments and Patient Dyspnea

NCT07701850
View directory record Official record
Conditions
Respiratory Failure, Dyspnea During Mechanical Ventilation, Mechanical Ventilation
Interventions
Change to VC/AC, Change in Tidal Volume, Change in inspiratory flow, Change in PEEP, Change to PSV
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 22, 2026, 5:50 AM EDT
Completed No phase listed Observational Results available

Physiological Flow of Liquids Used in Dysphagia Management (Neuro)

NCT03192358
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Parkinson Disease, Dysphagia
Interventions
Videofluoroscopic Swallowing Examination, Tongue Strength Measurement
Diagnostic Test · Other
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2022 · Synced Oct 22, 2026, 5:50 AM EDT
Enrolling by invitation Not applicable Interventional

Postbiotics for Mitigation of Postoperative Dysbiosis in Gastrointestinal Cancer Surgery

NCT07050485
View directory record Official record
Conditions
Colon Cancer, Gastrointestinal Cancer
Interventions
PoZibio, Inert placebo
Dietary Supplement
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Oct 22, 2026, 5:50 AM EDT
Active, not recruiting Phase 2 Interventional

Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ

NCT03935685
View directory record Official record
Conditions
Glioma of Brain
Interventions
Mirtazapine (Remeron)
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2030
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Oct 22, 2026, 5:50 AM EDT
Withdrawn Early Phase 1 Interventional

Pilot Study Evaluating Tumor Microenvironment Interaction in Solid Tumor Patients

NCT06922825
View directory record Official record
Conditions
Solid Tumor Cancer, Solid Tumor Malignancy, Cancer, Malignancy
Interventions
68Ga-FAPI-46
Drug
Lead sponsor
Eben Rosenthal
Other
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 22, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Center for Stroke Disparities Solution - Community Transitions Intervention

NCT01918891
View directory record Official record
Conditions
Hypertension, Stroke, Transient Ischemic Attack
Interventions
Nurse Practitioner Only, Nurse Practitioner + Health Coach
Behavioral
Lead sponsor
Visiting Nurse Service of New York
Other
Eligibility
21 Years and older
Enrollment
495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Oct 22, 2026, 5:50 AM EDT
Withdrawn Phase 2 Interventional

HIPEC as Neoadjuvant Treatment for Resectable Pancreatic Adenocarcinoma

NCT02850874
View directory record Official record
Conditions
Pancreatic Neoplasms, Pancreatic Adenocarcinoma
Interventions
Hyperthermic intraperitoneal chemotherapy, Open pancreaticoduodenectomy, Gemcitabine
Procedure · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 22, 2026, 5:50 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

MagniXene MRI Use in Patients With Asthma and COPD to Assess Regional Lung Function by Delineating Ventilation Defects

NCT01833390
View directory record Official record
Conditions
Asthma, COPD, Healthy
Interventions
HXe MRI lung ventilation
Drug
Lead sponsor
Xemed LLC
Industry
Eligibility
21 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 11, 2015 · Synced Oct 22, 2026, 5:50 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Non-invasive Measurement of Cerebrovascular Reactivity After Traumatic Brain Injury

NCT02990078
View directory record Official record
Conditions
TBI
Interventions
Sildenafil citrate, Functional Near Infared Spectroscopy, Hypercapnia Challenge
Drug · Device · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Oct 22, 2026, 5:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alveolar Ridge Preservation Procedures

NCT05419778
View directory record Official record
Conditions
Alveolar Ridge Preservation
Interventions
Osteogen plug®, MInerOss®
Device
Lead sponsor
University of Tennessee
Other
Eligibility
12 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 22, 2026, 5:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Evaluation of Tailored Messages to Address Parental Questions About HPV Vaccination

NCT03628885
View directory record Official record
Conditions
Human Papilloma Virus Vaccines, Attitude to Health
Interventions
Top Concern Tailored Intervention, All Concerns Tailored Intervention
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
908 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 2, 2019 · Synced Oct 22, 2026, 5:50 AM EDT
Not listed Not applicable Interventional

Remote Ischemic Conditioning in Abdominal Surgery

NCT03234543
View directory record Official record
Conditions
Laparotomy, Laparoscopy, Retroperitoneal Disease, Pelvis Disease, Pancreatic Diseases, Liver Diseases, Gastrointestinal Disease, Urologic Diseases, Complication of Surgical Procedure
Interventions
Remote ischemic conditioning, No Remote ischemic conditioning
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Oct 22, 2026, 5:50 AM EDT
Completed Not applicable Interventional

Novel Cardiac Pacing to Initiate Cardiac Remodeling in Heart Failure

NCT05600725
View directory record Official record
Conditions
Cardiomyopathies, Heart Rate, Conditioning
Interventions
novel atrial pacing approach, sham pacing approach
Other
Lead sponsor
Denise Hodgson-Zingman
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Oct 22, 2026, 5:50 AM EDT
Active, not recruiting Not applicable Interventional

Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)

NCT05743517
View directory record Official record
Conditions
Ovary Cancer, Endometrial Cancer, Uterine Cancer, Cervical Cancer, Cervix Cancer, Vulvar Cancer, Vaginal Cancer
Interventions
Fit4Treatment
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years and older · Female only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 22, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

PrEP4U: Assessing the Effectiveness of Integrated Same-Day Lenacapavir Initiation and Follow-up Choice on PrEP Persistence

NCT07335289
View directory record Official record
Conditions
HIV Pre-exposure Prophylaxis Use
Interventions
Choice of follow up, Follow up via standard clinic
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 22, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Development of an mHealth Behavioral Sleep Medicine Intervention for Use During Medication Assisted Treatment for MOUD

NCT06157840
View directory record Official record
Conditions
Opioid Use Disorder, Poor Quality Sleep
Interventions
mHealth application and sleep health education, Simplified mHealth application and sleep health education
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 22, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using Middle School Science Teachers to Address Cancer Health Disparities

NCT07501689
View directory record Official record
Conditions
Cancer Risk Factors, Cancer Prevention
Interventions
CARES4You Curriculum
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
10 Years and older
Enrollment
1,812 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
5
States / cities
Brooklyn, New York • New York, New York • Queens, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 22, 2026, 5:50 AM EDT
Recruiting Not applicable Interventional

Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits

NCT06728774
View directory record Official record
Conditions
Major Depressive Disorder (MDD), Cognitive Dysfunction
Interventions
Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD), Goal-focused Supportive Contact
Behavioral
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 22, 2026, 5:50 AM EDT