Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:17 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 87 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: SBIRT+ Clear all

Conditions: Alcohol Use Disorder, Substance Use, Alcohol Abuse or Dependence
Interventions: Vivitrol (Extended Release Naltrexone); Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older
Enrollment: 179 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Pain, Substance Use, Opioid Misuse, Quality of Life
Interventions: M2VA Pain Care Pathway (M2VAPCP), Implementation Facilitation; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 1,800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Substance Abuse
Interventions: Not listed
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 14 Years to 17 Years
Enrollment: 514 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Substance Use Disorders, Mental Illness
Interventions: SBIRT, Health Education; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 1,080 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 2
States / cities: Los Angeles, California • Oxnard, California

Conditions: Opiate Addiction
Interventions: Brief Negotiation Interview (BNI), Buprenorphine Initiation; Behavioral · Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 329 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Substance Use
Interventions: Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI), Standard Referral to Treatment (RT), Family Screening, Family Psychoeducation, Family Brief Negotiated Interview (BNI), Family Facilitated Conversation (FC) & Referral to Treatment (RT); Behavioral
Lead sponsor: The National Center on Addiction and Substance Abuse at Columbia University; Other
Eligibility: 12 Years to 17 Years
Enrollment: 2,300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: New York, New York

Conditions: Contraception
Interventions: SpeakOut, PartyWise; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 15 Years to 20 Years · Female only
Enrollment: 1,099 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Problem Drinking, Alcohol Dependence
Interventions: Brief Motivational Intervention; Behavioral
Lead sponsor: Public Health Institute, California; Other
Eligibility: 18 Years to 30 Years
Enrollment: 698 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: El Paso, Texas

Conditions: Drinking Behavior, Drinking Excessive, Drinking
Interventions: SBIRT; Behavioral
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older · Male only
Enrollment: 611 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Adolescent Health Services, Adolescent Behavior
Interventions: brief intervention, treatment as usual; Behavioral
Lead sponsor: Friends Research Institute, Inc.; Other
Eligibility: 12 Years to 17 Years
Enrollment: 1,226 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 4
States / cities: Lordsburg, New Mexico • Silver City, New Mexico • Adamsville, Tennessee + 1 more

Conditions: Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
Interventions: Screening, Brief Intervention, Referral to Treatment (SBIRT); Behavioral
Lead sponsor: Shirish S Barve; Other
Eligibility: 18 Years to 85 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Patients With Substance Abuse, Healthcare Provider Attitudes
Interventions: Training on motivational interviewing; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2011
U.S. locations: 2
States / cities: Birmingham, Alabama

Conditions: Pregnancy, Substance Use, Depression, Anxiety
Interventions: Listening to Women and Pregnant and Postpartum People; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 41 Years · Female only
Enrollment: 415 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alcohol Abuse
Interventions: Nutrition time control/placebo intervention, Computer-delivered, brief intervention on alcohol use; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Depression
Interventions: SBIRT, Referral as Usual; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 505 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 2
States / cities: New York, New York

Conditions: Substance Use Disorders
Interventions: Technology Augmented Treatment for Screening, Brief Intervention, Referral, and Treatment (SBIRT); Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 21 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Spokane Valley, Washington

Conditions: Transgender Women, Substance Abuse, Hiv
Interventions: Adapted SBIRT-T for transgender women; Behavioral
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years and older · Male only
Enrollment: 86 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 2
States / cities: Miami, Florida • Orlando, Florida

Conditions: Drug Use
Interventions: Usual Care, QUIT Intervention (doctor brief advice, video doctor, health coaching sessions at 2- and 6-weeks), QUIT-Mobile (QUIT Intervention plus weekly mobile-web app or text message weekly self-monitoring, automated feedback over 12 months); Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 457 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 5
States / cities: Long Beach, California • Los Angeles, California

Conditions: Substance Use Disorder (SUD), HIV
Interventions: ENTRUST - substance use and HIV counseling and goal setting with economic empowerment and photovoice training, SBIRT-T only; Behavioral
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years and older · Male only
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Mental Health Issue, Substance Use Disorders, Postpartum Depression, Postpartum Anxiety
Interventions: Listening to Women & Pregnant and Postpartum People; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 10,469 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
Interventions: Centralized Virtual SBIRT; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 12 Years to 17 Years
Enrollment: 22,320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Pleasanton, California

Conditions: Behavioral Health Challenges
Interventions: Screening, Brief Intervention and Referral for Treatment (SBIRT); Behavioral
Lead sponsor: Yale University; Other
Eligibility: 17 Years and older
Enrollment: 340 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
Interventions: Brief Intervention with NRT Initiation; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 780 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: HIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic Intoxication, Substance-Related Disorders
Interventions: Motivational Interviewing, Email Feedback, Usual Care; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 100 Years
Enrollment: 614 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: San Francisco, California

Search by objective public record fields.

Emergency Department Initiated Extended-Release Naltrexone and Case Management for the Treatment of Alcohol Use Disorder

M2VA Pain Care Pathway

Validating Adolescent SBIRT Measures

Screening, Brief Intervention and Referral to Treatment for Substance Abuse in Mental Health Treatment Settings

Models of Screening, Brief Intervention With a Facilitated Referral to Treatment (SBIRT) for Opioid Patients in the Emergency Department

Primary Connections for Youth and Families

The Share Health Study: Teen Social Connections and Health (Phase 2)

Screening and Brief Intervention in the ED Among Mexican-origin Young Adults

Barbershop Talk: Reducing Excessive Alcohol Consumption Among Men

Examining the Effectiveness of the FaCES Adolescent SBIRT Intervention

Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

Healthcare Provider Attitudes Towards Patients With Substance Use Before and After Implementation of the SBIRT Model in the Emergency Room

Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT

Computer-delivered Screening and Brief Intervention for Alcohol Use in Pregnancy

Depression Screening in Black Churches

Technologically-Augmented Referrals to Mitigate Addiction Consequences

To Reach Unrestricted Services for Transgender Women

mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care

ENTRUST - Economic Navigation and Strengthening to Realize Unrestricted Services for Transgender Women

Improving Maternal Mental Health & SUD Screening and Treatment

Centralized Virtual SBIRT for Pediatric Primary Care

Brief Intervention at Adult Education

Treating Low-Income Smokers in the Hospital Emergency Department

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients