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ClinicalTrials.gov public records Last synced Nov 15, 2026, 1:53 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 87 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: SBIRT+ Clear all

Conditions: Colorectal Cancer
Interventions: SBIRT, Referral as Usual (RAU); Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 45 Years and older
Enrollment: 880 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Depression
Interventions: Problem Solving Education and Activated Referral to Care; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 15 Years to 64 Years · Female only
Enrollment: 230 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Alcohol Abuse, Alcohol Dependence
Interventions: RBIRT, SBIRT; Behavioral
Lead sponsor: Polaris Health Directions; Industry
Eligibility: 18 Years and older
Enrollment: 330 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Alcohol Use Disorder
Interventions: Peer recovery coaching (PRC), Brief Intervention (SBIRT); Behavioral
Lead sponsor: Clemson University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 750 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Greenville, South Carolina • Seneca, South Carolina

Conditions: Suicide Prevention
Interventions: SBIRT+12, SBIRT+Usual Care; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 34 Years
Enrollment: 698 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Drug Use, Alcohol Use
Interventions: SBIRT+; Behavioral
Lead sponsor: Treatment Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 3
States / cities: Philadelphia, Pennsylvania

Conditions: Substance Use, HIV/AIDS, Older Adults, Behavioral Intervention, Infectious Disease
Interventions: Psycho-educational content (5 Minutes), Readiness Assessment (10 minutes), Goal-Setting (5 minutes), Identifying and prioritizing needs (5 minutes), Explanation of Peer Navigator and Session wrap (5 minutes); Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 3
States / cities: Gainesville, Florida • Jacksonville, Florida • Lake City, Florida

Conditions: Attendance at Treatment, PTSD, Substance Use, and Attendance at Treatment
Interventions: SBIRT; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 346 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2017
U.S. locations: 2
States / cities: West Haven, Connecticut • Nashville, Tennessee

Conditions: Adolescent Drinking, Adolescent Substance Use, Risk Behavior, Health
Interventions: Indicated Prevention, Clinical Staff, Selective Prevention, Expanded Paraprofessional Workforce; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 14 Years to 19 Years
Enrollment: 21,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Drug Abuse
Interventions: Screening/motivational drug intervention, Motivational placebo intervention; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 700 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 2
States / cities: San Diego, California

Conditions: Substance Use Disorders
Interventions: SBIRT Training and Implementation Strategies; Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 2,562 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Preconception Health
Interventions: SBIRT Intervention; Behavioral
Lead sponsor: Morehouse School of Medicine; Other
Eligibility: 18 Years to 44 Years
Enrollment: 850 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Housing Problems, Drug Use, Alcohol; Use, Problem
Interventions: Referral to homelessness prevention services, Substance use services, Follow-up; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance Use, Substance Abuse, Substance-Related Disorders
Interventions: Processing of clinical notes in the EHR data collected during routine care; Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 89 Years
Enrollment: 64,996 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Opioid-use Disorder, Contingency Management, Medication for Opioid-use Disorder
Interventions: Software Application; Other
Lead sponsor: Q2i, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Contraception
Interventions: SpeakOut, Alcohol Control Intervention; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 15 Years to 19 Years · Female only
Enrollment: 207 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Davis, California • Los Angeles, California

Conditions: Substance Related Disorders
Interventions: cSBA - New England, USA, cSBA - Prague, CZR; Behavioral
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 12 Years to 18 Years
Enrollment: 2,695 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 5
States / cities: Boston, Massachusetts • Cambridge, Massachusetts • Worcester, Massachusetts + 2 more

Conditions: Alcohol Dependency
Interventions: SBIRT; Behavioral
Lead sponsor: San Diego State University; Other
Eligibility: 18 Years and older
Enrollment: 791 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: San Diego, California

Conditions: Drug Abuse
Interventions: Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET), Enhanced Usual Care (EUC); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 60 Years
Enrollment: 878 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Substance Use Disorders
Interventions: Connect2BWell; Behavioral
Lead sponsor: Pro-Change Behavior Systems; Other
Eligibility: 18 Years and older
Enrollment: 237 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Middletown, Connecticut • South Kingstown, Rhode Island

Conditions: Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder, Stimulant Use & Co-occuring Opioid Use Disorders, Co-occurring Mental and Substance Use Disorders, Medications for Opioid Use Disorder
Interventions: Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET); Other
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older
Enrollment: 338 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Little Rock, Arkansas

Conditions: Gambling Disorder
Interventions: SBIRT for Gambing, Enhanced Control; Behavioral · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 90 Years
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Marijuana Use, Pregnancy
Interventions: eSBIRT, Tailored texting; Behavioral
Lead sponsor: Wayne State University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: HIV Infections, Alcohol Use Disorder, Violence, Gender-Based
Interventions: PrEP for WINGS, PrEP Decision Aid; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 307 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk

Preventing Maternal Depression In Head Start

Remote Brief Intervention and Referrals to Treatment Service for Alcohol

A Peer Recovery Coaching Intervention for Hospitalized Alcohol Use Disorder Patients

Suicide in Urban Natives: Detection and Networks to Combat Events

Integrating Substance Abuse Assessment & Intervention in Primary Care Settings

Feasibility of SBIRT-PN

Evaluation and Treatment of Substance Abuse in Veterans With PTSD Disability Claims

Optimizing and Advancing SBIRT in Schools

Screening, Brief Intervention, and Referral to Treatment for Drug Use

Implementation and Evaluation of SBIRT

Involving Communities in Addressing the Maternal Health Crisis: Making an IMPACT

ED-Home Pilot Study

Data-driven Identification for Substance Misuse

Usability Testing for the Reward-based Technology to Improve OUD Treatment

The Share Health Study: Teen Social Connections and Health

Screening and Brief Advice to Reduce Teen Substance Use

Alcohol Screening, Brief Intervention, and Referral to Treatment in a Military Treatment Facility

Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department

Connect2BWell: An Evidence-Based Screening, Brief Intervention, and Referral to Treatment (SBIRT) Program

Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails

SBIRT Intervention for Gambling Behaviors

Computer-delivered Screening & Brief Intervention for Marijuana Use in Pregnancy

An Effectiveness Trial of the PrEP for WINGS Study