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ClinicalTrials.gov public records Last synced Sep 9, 2026, 9:32 AM EDT

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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: SCS trial lead Clear all
Enrolling by invitation Not applicable Interventional

Efficacy and Feasibility of BurstDR SCS in Painful Diabetic Neuropathy

NCT07250828
View directory record Official record
Conditions
Painful Diabetic Neuropathy (PDN), Diabetic Neuropathy, Neuropathic Pain, Chronic Pain
Interventions
BurstDR Spinal Cord Stimulation
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 9, 2026, 9:32 AM EDT
Completed No phase listed Observational

NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators

NCT02284542
View directory record Official record
Conditions
Chronic Pain, Sciatica, Failed Back Surgery Syndrome
Interventions
Awake, Non-Awake
Procedure
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
4
States / cities
Bethlehem, Pennsylvania • Danville, Pennsylvania • Hershey, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Sep 9, 2026, 9:32 AM EDT
Completed Not applicable Interventional Results available

High Rate Spinal Cord Stimulation (SCS) for Chronic Pain

NCT01624740
View directory record Official record
Conditions
Chronic Pain
Interventions
Low Rate Stimulation, High Rate Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Mar 19, 2015 · Synced Sep 9, 2026, 9:32 AM EDT
Completed Not applicable Interventional

Lead Migration in Spinal Cord Stimulation Trials: Comparing Non-suture vs Suture and Lead Anchor

NCT01126983
View directory record Official record
Conditions
Spinal Cord Stimulation
Interventions
Suture, Lead Anchor
Device
Lead sponsor
Spine Care, Oklahoma
Other
Eligibility
18 Years to 95 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 8, 2010 · Synced Sep 9, 2026, 9:32 AM EDT
Terminated Not applicable Interventional

Clinical Evaluation of Direct Dorsal Column Stimulation

NCT02020460
View directory record Official record
Conditions
Failed Back Surgery Syndrome
Interventions
Subdural trial lead, Epidural trial lead
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 7, 2017 · Synced Sep 9, 2026, 9:32 AM EDT
Completed Not applicable Interventional Results available

Evaluating Spinal Cord Stimulation for Stiff Person Syndrome

NCT06242678
View directory record Official record
Conditions
Stiff-Person Syndrome
Interventions
SCS trial lead
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 9, 2026, 9:32 AM EDT
Completed Not applicable Interventional Results available

Quantitative Assessment of Painful Diabetic Peripheral Neuropathy After High Frequency Spinal Cord Stimulation

NCT03769675
View directory record Official record
Conditions
Painful Diabetic Neuropathy
Interventions
High Frequency Spinal Cord Stimulator
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Sep 9, 2026, 9:32 AM EDT
Terminated Not applicable Interventional Results available

Evaluation of the Percutaneous SCS Trial Using the DSSEP Collision Testing

NCT02614079
View directory record Official record
Conditions
Back Pain With Radiation
Interventions
DSSEP
Device
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced Sep 9, 2026, 9:32 AM EDT
Withdrawn Not applicable Interventional

A Prospective Trial for the Effectiveness of the Use of Spinal Cord Stimulation (SCS) in Failed Knee Surgery

NCT01912924
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal cord stimulator (Boston Scientific)
Device
Lead sponsor
Coastal Orthopedics & Sports Medicine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 30, 2013 · Synced Sep 9, 2026, 9:32 AM EDT
Completed Not applicable Interventional Results available

Study to Evaluate Automated Intensity Management in Patients Undergoing a BSC SCS Temporary Trial

NCT04909593
View directory record Official record
Conditions
Chronic Pain, Intractable Pain, Low Back Pain, Pain, Neuropathic, Pain, Back
Interventions
Spinal Cord Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 9, 2026, 9:32 AM EDT
Completed Not applicable Interventional Results available

A Safety and Effectiveness Trial of Spinal Cord Stimulation of the Dorsal Root Ganglion for Chronic Lower Limb Pain

NCT01923285
View directory record Official record
Conditions
Chronic Lower Limb Pain
Interventions
AXIUM Neurostimulator System, Control Spinal Cord Stimulation Device
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
22 Years to 75 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
22
States / cities
Phoenix, Arizona • Aptos, California • Carlsbad, California + 19 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Sep 9, 2026, 9:32 AM EDT
Active, not recruiting Not applicable Interventional

PDN Post Market, Multicenter, Prospective, Global Clinical Study

NCT05301816
View directory record Official record
Conditions
Diabetic Neuropathy, Painful
Interventions
Spinal Cord Stimulator (SCS)
Device
Lead sponsor
Nevro Corp
Industry
Eligibility
18 Years and older
Enrollment
497 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
8
States / cities
Anchorage, Alaska • Ann Arbor, Michigan • West Bloomfield, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 9, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional

A Prospective Evaluation of Spinal Cord Induced Muscle Stimulation (MuscleSCS) for the Treatment of Chronic Low Back Pain

NCT07215104
View directory record Official record
Conditions
Chronic Low Back Pain (CLBP)
Interventions
MuscleSCS
Device
Lead sponsor
Saint Francis Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 9, 2026, 9:32 AM EDT
Recruiting No phase listed Observational

Improving Spinal Cord Stimulation With ECAPS

NCT04938245
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal Cord Stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 9, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional

Sensory Spinal Cord Stimulation

NCT07095036
View directory record Official record
Conditions
Pain Management, Pain, Intractable, Pain, Chronic Disease
Interventions
Spinal cord stimulation (SCS)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 9, 2026, 9:32 AM EDT
Active, not recruiting Not applicable Interventional Results available

Comparing Long-term Effectiveness of High Frequency and Burst Spinal Cord Stimulation

NCT03681262
View directory record Official record
Conditions
Chronic Pain
Interventions
High frequency spinal cord stimulation, Burst spinal cord stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 9, 2026, 9:32 AM EDT
Enrolling by invitation Not applicable Interventional

Medtronic Inceptiv™ Closed-Loop DTM Spinal Cord Stimulation for Painful Diabetic Peripheral Neuropathy

NCT07209514
View directory record Official record
Conditions
Diabetic Peripheral Neuropathic Pain (DPN)
Interventions
Implantable SCS with Closed Loop mechanism
Device
Lead sponsor
TriCity Research Center
Industry
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Grand Island, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 9, 2026, 9:32 AM EDT
Active, not recruiting No phase listed Observational

Epidural Spinal Cord Stimulation for Hypertension in Patients With Neuropathic Pain

NCT04598035
View directory record Official record
Conditions
Chronic Pain, Hypertension, Implanted Stimulation Electrodes
Interventions
Diagnostic Tests
Diagnostic Test
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
30 Years to 89 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Fairway, Kansas • Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 9, 2026, 9:32 AM EDT
Terminated Not applicable Interventional Results available

Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity

NCT00399841
View directory record Official record
Conditions
Intractable Neuropathic Pain, Pain, Back Pain, Lower Extremity Pain
Interventions
Precision for Spinal Cord Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Belleville, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2020 · Synced Sep 9, 2026, 9:32 AM EDT
Not listed Not applicable Interventional

Lead Migration During the Spinal Cord Stimulation Trial Period and Therapeutic Response

NCT05956548
View directory record Official record
Conditions
Spinal Cord Stimulator Trial Period, Neuromodulation Trial Period, SCS Trial Period
Interventions
external securement of scs leads during the scs trial period
Procedure
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Sep 9, 2026, 9:32 AM EDT
Completed Not applicable Interventional

The RESET Clinical Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Back Pain

NCT04246281
View directory record Official record
Conditions
Low Back Pain, Back Pain
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System, Standard interventional management of low back pain
Device · Procedure
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years to 75 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
18
States / cities
Little Rock, Arkansas • Walnut Creek, California • Greenwood Village, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 9, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation and Small Fiber Peripheral Neuropathy

NCT06287736
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Spinal Cord Stimulator Implantation (SCS)
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 9, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional

Prospective Evaluation of Effectiveness and Safety of Closed-Loop Spinal Cord Stimulation in Treating Patients With Chronic Pelvic Pain

NCT06377969
View directory record Official record
Conditions
Chronic Pelvic Pain Syndrome
Interventions
ECAP (Evoked Compound Action Potential)-controlled Closed-Loop Spinal Cord Stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 9, 2026, 9:32 AM EDT
Suspended Not applicable Interventional

The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage

NCT06443177
View directory record Official record
Conditions
Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage
Interventions
Vectris trial leads and stimulation, Sham
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 9, 2026, 9:32 AM EDT