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ClinicalTrials.gov public records Last synced Nov 7, 2026, 1:23 PM EST

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Showing 1–24 of 137 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: SHIELD Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

The Utility of a Novel Eye Shield With Reusable Adhesive Anchors for Post-operative Care After Ophthalmic Surgery

NCT05957796
View directory record Official record
Conditions
Cataract; Eye Disease
Interventions
Novel "Snaps" Eye Shield, Standard Alcon Eye Shield
Device · Other
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Nov 7, 2026, 1:23 PM EST
Completed Early Phase 1 Interventional

Digestive Endoscopy Suite Radiation Controlling Protective Strategies

NCT02063841
View directory record Official record
Conditions
Radiation Exposure
Interventions
lead-free protective drape containing bismuth and antimony (RADPAD®), sterile identical sham drape
Device
Lead sponsor
Yale University
Other
Eligibility
45 Years to 50 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
New Have, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 20, 2015 · Synced Nov 7, 2026, 1:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users

NCT01334736
View directory record Official record
Conditions
Tobacco Dependence
Interventions
Usual care, Lung age, Contingency Management, Lung age + Contingency Management
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Nov 7, 2026, 1:23 PM EST
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Decision Counseling and Follow-up for Shield+ Patients

NCT07620535
View directory record Official record
Conditions
Colo-rectal Cancer
Interventions
Decision Counseling Session
Behavioral
Lead sponsor
Guardant Health, Inc.
Industry
Eligibility
45 Years to 75 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Nov 7, 2026, 1:23 PM EST
Not yet recruiting Phase 1 Interventional

Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau

NCT06600880
View directory record Official record
Conditions
Alzheimer Disease, Early Onset
Interventions
Neuronavigation-guided single-element focused ultrasound transducer, Lumason, Magnetic Resonance Imaging (MRI) with or without gadolinium contrast agents, Positron Emission Tomography (PET), Amyvid, MK-6240, Dotarem, Blood draw, UR5e, Urine test
Device · Drug · Other + 2 more
Lead sponsor
Columbia University
Other
Eligibility
50 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Nov 7, 2026, 1:23 PM EST
Recruiting Phase 2 Interventional

SARS-CoV-2 and Herpesvirus Inhibition for Ending Long COVID Dysfunction

NCT07597902
View directory record Official record
Conditions
Post-acute Sequelae of COVID-19, Long COVID
Interventions
Valacyclovir, Celecoxib, Paxlovid, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 28, 2026 · Synced Nov 7, 2026, 1:23 PM EST
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers

NCT02355002
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Nov 7, 2026, 1:23 PM EST
Recruiting Not applicable Interventional

Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder

NCT06415721
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Abuse, Alcoholism, Drinking Behavior, Drinking Problem
Interventions
Active Transcranial Magnetic Simulation, Sham
Device
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
25 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Nov 7, 2026, 1:23 PM EST
Terminated Phase 1 Interventional Results available

Novel Antiaging Regenerative Skin Care Regimen Containing Human Platelet Extract (HPE)

NCT05457491
View directory record Official record
Conditions
Skin Aging
Interventions
Human platelet extract (cosmetic product), Vanicream Gentle Facial Cleanser, EltaMD UV Daily Broad-Spectrum SPF 40, EltaMD PM Therapy Facial Moisturizer, Vanicream Lite Lotion
Biological · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Nov 7, 2026, 1:23 PM EST
Completed Not applicable Interventional

System for High-Intensity Evaluation During Radiotherapy

NCT04277650
View directory record Official record
Conditions
Radiation Therapy Complication, Chemotherapeutic Toxicity
Interventions
Machine learning algorithm
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
311 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Nov 7, 2026, 1:23 PM EST
Active, not recruiting Not applicable Interventional

Evaluation of Flow Diverter Technology Device for Intracranial Aneurysm

NCT06411418
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Pipeline™ Flex Embolization Device with Shield Technology™
Device
Lead sponsor
Jacobs institute
Other
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Nov 7, 2026, 1:23 PM EST
Terminated Phase 3 Interventional Results available

38 Week Extension Study to CAIN457C2303

NCT01093846
View directory record Official record
Conditions
Uveitis
Interventions
AIN457, Placebo AIN457
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 100 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Nov 7, 2026, 1:23 PM EST
Recruiting Phase 2 Interventional

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody

NCT06358638
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Daratumumab, Alemtuzumab, Sirolimus, Total Body Irradiation
Drug · Radiation
Lead sponsor
Children's National Research Institute
Other
Eligibility
2 Years to 25 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2054
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Nov 7, 2026, 1:23 PM EST
Completed Phase 2 Interventional Results available

A Phase II Study of 131I- Metaiodobenzylguanidine (MIBG) for Treatment of Metastatic or Unresectable Pheochromocytoma and Related Tumors

NCT01413503
View directory record Official record
Conditions
Pheochromocytoma, Paraganglioma
Interventions
131I-MIBG
Radiation
Lead sponsor
University of California, San Francisco
Other
Eligibility
4 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1991 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2018 · Synced Nov 7, 2026, 1:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tick-borne Illness and Clothing Study

NCT01454414
View directory record Official record
Conditions
Tick Bites, Tick-borne Illness
Interventions
Permethrin Impregnated Uniforms
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 30, 2021 · Synced Nov 7, 2026, 1:23 PM EST
Completed Not applicable Interventional

Normalizing HPV Vaccination in Preteens With a Serious Video Game

NCT04627298
View directory record Official record
Conditions
Human Papillomavirus
Interventions
educational video game for preteens to support HPV vaccination
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
11 Years to 12 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 13, 2020 · Synced Nov 7, 2026, 1:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

OA Therapy for Mouth-breathers Who Snore

NCT04876625
View directory record Official record
Conditions
Snoring, Mouth Breathing, Obstructive Sleep Apnea
Interventions
myTAP oral appliance plus mouth shield, myTAP oral appliance alone for first 4 weeks
Device
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Nov 7, 2026, 1:23 PM EST
Enrolling by invitation No phase listed Observational

Advanced Materials Science in XLIF Study

NCT03649490
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis
Interventions
Not listed
Lead sponsor
NuVasive
Industry
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
15
States / cities
Hartford, Connecticut • Jacksonville, Florida • Tampa, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Nov 7, 2026, 1:23 PM EST
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Guardant Shield Colorectal Cancer Screening

NCT07436637
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Screening Reminder, Blood Sample Collection
Behavioral · Procedure
Lead sponsor
University of Miami
Other
Eligibility
45 Years to 85 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Nov 7, 2026, 1:23 PM EST
Not listed Not applicable Interventional Accepts healthy volunteers

PRINT Trial (Platelet Rich Injection vs Needle Tenotomy)

NCT03504111
View directory record Official record
Conditions
Lateral Epicondylitis, Tendinosis, Elbow, Tennis, Elbows Tendonitis
Interventions
Percutaneous Needle Tenotomy, PRP
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Nov 7, 2026, 1:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Promotion of Successful Parenting

NCT03808987
View directory record Official record
Conditions
Pregnant and Parenting Women
Interventions
Child-Parent Psychotherapy (CPP), Community Health Worker (CHW) home visitation
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older · Female only
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Nov 7, 2026, 1:23 PM EST
Completed Not applicable Interventional Results available

Xylitol for Caries Prevention in Inner-City Children

NCT01901250
View directory record Official record
Conditions
Dental Caries
Interventions
Xylitol gummy bears, Sugar free fiber gummy bears, Oral health education, Fluoride varnish, Dental sealant
Dietary Supplement · Behavioral · Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
5 Years to 6 Years
Enrollment
562 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 12, 2014 · Synced Nov 7, 2026, 1:23 PM EST
Completed Phase 1 Interventional Accepts healthy volunteers

Bemotrizinol UV Filter Part 1 Clinical PK Evaluation in Topical MUsT Study

NCT04355286
View directory record Official record
Conditions
Absorption; Chemicals, Sunscreening Agents
Interventions
Bemotrizinol
Drug
Lead sponsor
dsm-firmenich Switzerland AG
Industry
Eligibility
18 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
West Bend, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Nov 7, 2026, 1:23 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Laser Vision Correction Use of an Eye Shield for Maintaining Vision and Mitigating Pain

NCT01675375
View directory record Official record
Conditions
Post Laser Vision Correction Pain and Discomfort
Interventions
Eye Shield
Device
Lead sponsor
FORSIGHT Vision3
Industry
Eligibility
18 Years to 60 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
5
States / cities
San Diego, California • Chicago, Illinois • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2013 · Synced Nov 7, 2026, 1:23 PM EST