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ClinicalTrials.gov public records Last synced Nov 3, 2026, 2:13 PM EST

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Showing 25–48 of 589 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: SIGNAL Clear all
Terminated Phase 1Phase 2 Interventional

Feasibility of the LUM Imaging System for Detection of Prostate Cancer

NCT03441464
View directory record Official record
Conditions
Prostate Cancer, Neoplasm, Residual
Interventions
LUM Imaging System
Combination Product
Lead sponsor
Lumicell, Inc.
Industry
Eligibility
40 Years and older · Male only
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 25, 2022 · Synced Nov 3, 2026, 2:13 PM EST
Withdrawn Not applicable Interventional

An Osseoanchored Percutaneous Prosthesis Study Evaluating Stable Neural Signal Transmission in Subjects With Transhumeral Amputations

NCT03957226
View directory record Official record
Conditions
Amputation Neuroma, Amputation, Prosthesis User
Interventions
e-OPRA (electronic-Osseoanchored Prosthese for the Rehabilitation of Amputees)
Device
Lead sponsor
University of Michigan
Other
Eligibility
22 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Nov 3, 2026, 2:13 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Cash Plus Interventions for Prevention of Acute Malnutrition in Children Under 5 and Their Mothers in Somalia

NCT06642012
View directory record Official record
Conditions
Malnutrition, Child, Wasting Disease, Stunting, Malnutrition, Malnutrition, Mother
Interventions
Cash only, Cash + Social Behavior Change Communication, Cash + top-up cash
Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
6 Months and older
Enrollment
3,384 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Nov 3, 2026, 2:13 PM EST
Completed No phase listed Observational

A Study of Detection of Paroxysmal Events Utilizing Computer Vision and Machine Learning - Nelli

NCT05606575
View directory record Official record
Conditions
Epilepsy
Interventions
Nelli
Device
Lead sponsor
Neuro Event Labs Inc.
Industry
Eligibility
6 Years to 21 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Nov 3, 2026, 2:13 PM EST
Completed No phase listed Observational

The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients

NCT01319630
View directory record Official record
Conditions
Severe Sepsis, Septic Shock, Microcirculation
Interventions
Sidestream Dark Field (SDF), Near Infrared Spectroscopy (NIRS)
Device
Lead sponsor
Mercy Research
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 26, 2017 · Synced Nov 3, 2026, 2:13 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Finger Muscle Reaction After Electrical Stimuli to the Human Finger Pulley System; a Pilot Study

NCT01456871
View directory record Official record
Conditions
Healthy
Interventions
Guided insertion of electrodes, Electromyographic (EMG) recording
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 30 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 10, 2013 · Synced Nov 3, 2026, 2:13 PM EST
Completed Early Phase 1 Interventional Accepts healthy volunteers

Selective Nerve Stimulation (SNS) Pilot Study

NCT01259271
View directory record Official record
Conditions
Healthy, Pain
Interventions
Selective Nerve Stimulation (SNS) stimulator device
Device
Lead sponsor
Codman & Shurtleff
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Raynham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 18, 2019 · Synced Nov 3, 2026, 2:13 PM EST
Completed Phase 1 Interventional

LY3214996 in Patients With AML Who Are Not Candidates for Standard Therapy

NCT04081259
View directory record Official record
Conditions
Acute Myeloid Leukemia
Interventions
LY3214996
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Nov 3, 2026, 2:13 PM EST
Terminated Phase 2 Interventional Results available

Bempegaldesleukin (NKTR-214) With Radiation and Anti-PD-1 Immunotherapy for Head and Neck Squamous Cell Carcinoma

NCT04936841
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
NKTR-214, anti-PD-1 therapy, Palliative Radiation
Drug · Radiation
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Nov 3, 2026, 2:13 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Real-time Biofeedback With 7-Tesla MRI for Treatment of Depression

NCT04138680
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Active Biofeedback, Sham Biofeedback
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Nov 3, 2026, 2:13 PM EST
Active, not recruiting Not applicable Interventional

Technology-supported Motor Rehabilitation for People With Rett Syndrome

NCT07418905
View directory record Official record
Conditions
Rett Syndrome
Interventions
computer gaming
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
4 Years to 65 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 28, 2026 · Synced Nov 3, 2026, 2:13 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Isolating and Mitigating Sequentially Dependent Perceptual Errors in Clinical Visual Search

NCT04332783
View directory record Official record
Conditions
Vision
Interventions
psychophysics of sequential biases (no drug or patient work)
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years and older
Enrollment
10,120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2032
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Nov 3, 2026, 2:13 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Cochlear Implants and Listening Effort: the Interaction of Cognitive and Sensory Constraints

NCT07279441
View directory record Official record
Conditions
Cochlear Implant Users
Interventions
Experiment 1: Syntactic and Semantic Context, Experiment 2: False Hearing and Context Overuse, Experiment 3: Two-Sentence Problem, Experiment 4: Cascading Effects on Discourse Comprehension, Experiment 5: Self-Paced Discourse Comprehension, Experiment 6: Clinical Application
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
2
States / cities
Waltham, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 30, 2026 · Synced Nov 3, 2026, 2:13 PM EST
Recruiting Phase 3 Interventional

Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ

NCT04722692
View directory record Official record
Conditions
DCIS, Breast Cancer, Breast Neoplasms, Sentinel Lymph Node
Interventions
Delayed SLND, Late SLND
Diagnostic Test
Lead sponsor
Uppsala University
Other
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Nov 3, 2026, 2:13 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Dementia Signal Development Study of Nautilus NeuroWave TM for the Detection of Dementia

NCT02333942
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Frontotemporal Lobar Degeneration, Memory Disorders
Interventions
Nautilus NeuroWaveTM System
Device
Lead sponsor
Jan Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Nov 3, 2026, 2:13 PM EST
Not listed Not applicable Interventional

EEG Brain-Machine Interface Control of an Upper-Limb Robotic Exoskeleton for Robot-Assisted Rehabilitation After Stroke

NCT05374486
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
NeuroExo co-robot neurorehabilitation system
Device
Lead sponsor
University of Houston
Other
Eligibility
20 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
3
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Nov 3, 2026, 2:13 PM EST
Recruiting Phase 2 Interventional Accepts healthy volunteers

Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV

NCT02560805
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Microneurography, Combat virtual reality video clip, Handgrip Exercise, Cold Pressor Test (CPT), Sodium Nitroprusside (SNP), Phenylephrine, Losartan, Atenolol, Transcutaneous Vagal Nerve Stimulation (tVNS), Sham Transcutaneous Vagal Nerve Stimulation (tVNS)
Procedure · Behavioral · Drug + 1 more
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Nov 3, 2026, 2:13 PM EST
Enrolling by invitation Not applicable Interventional

A Study Of Subscalp Placement Of The LINQII Device

NCT07752251
View directory record Official record
Conditions
Cranial Neurosurgery
Interventions
Medtronic LINQII
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Nov 3, 2026, 2:13 PM EST
Recruiting Not applicable Interventional

Neurofeedback From the Supplementary Motor Area for Tourette Syndrome

NCT05558566
View directory record Official record
Conditions
Tourette Syndrome in Adolescence
Interventions
Neurofeedback from the SMA, Neurofeedback from control region
Other
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Nov 3, 2026, 2:13 PM EST
Recruiting Phase 1Phase 2 Interventional

Psilocybin-Assisted Therapy for Physician Well-Being and Burnout

NCT06814522
View directory record Official record
Conditions
Burnout, Burnout, Healthcare Workers
Interventions
Psilocybin, [3-[2-(dimethylamino)ethyl]-1H-indol-4-yl] dihydrogen phosphate, Real-time Biofeedback
Drug · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Nov 3, 2026, 2:13 PM EST
Completed Phase 1 Interventional

A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer

NCT05249426
View directory record Official record
Conditions
Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions
BI 765063, Ezabenlimab, BI 836880, Cetuximab, Investigator´s Choice Chemotherapy
Drug · Other
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Nov 3, 2026, 2:13 PM EST
Not listed No phase listed Observational

Magnetocardiography as a Noninvasive Diagnostic Strategy for Identifying Coronary Allograft Vasculopathy

NCT05751915
View directory record Official record
Conditions
Coronary Allograft Vasculopathy (CAV)
Interventions
CardioFlux
Device
Lead sponsor
Genetesis Inc.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Nov 3, 2026, 2:13 PM EST
Completed Not applicable Interventional

Significance and Outcome of Magnetic Resonance Enterography Revealing Sacroiliitis in Crohn's Disease: A Pilot Study

NCT05203926
View directory record Official record
Conditions
Sacroiliitis
Interventions
MRI scan
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced Nov 3, 2026, 2:13 PM EST
Completed No phase listed Observational

Telemedicine Continuous Remote Monitoring of Adults With Uncontrolled Diabetes Mellitus

NCT05161793
View directory record Official record
Conditions
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Interventions
Tele-Monitor DM
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Nov 3, 2026, 2:13 PM EST