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ClinicalTrials.gov public records Last synced Oct 19, 2026, 2:49 PM EDT

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Showing 25–48 of 299 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: SMART Device Clear all
Not yet recruiting Not applicable Interventional

Cryoneurolysis in Anterior Cruciate Ligament Reconstruction (ACLR)

NCT07731178
View directory record Official record
Conditions
ACL Reconstruction (ACLR) With a Bone-patellar Tendon-bone (BPTB) Autograft
Interventions
Pacira Iovera Cryoneurolysis device, Placebo/Sham device
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 45 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 19, 2026, 2:49 PM EDT
Enrolling by invitation Not applicable Interventional

Using a Smart Implantable Device to Compare Early Recovery in Two Different Knee Arthroplasty Approaches

NCT07348835
View directory record Official record
Conditions
Total Knee Anthroplasty
Interventions
Total Knee Arthroplasty Medial Parapatellar Approach, Total Knee Arthroplasty Subvastus Approach
Procedure
Lead sponsor
Total Joint Specialists
Network
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sandy Springs, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 19, 2026, 2:49 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

OstiSense Biosensor in Bruxism Reduction - A Clinical Study

NCT03749928
View directory record Official record
Conditions
Bruxism, Sleep
Interventions
OstiSense biosensor - active, OstiSensor biosensor - not activated
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional

Artificial Pancreas With Different Stress Assessments in the Outpatient Setting

NCT04142229
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
iAPS, Sensor-Augmented Pump
Device · Other
Lead sponsor
Sansum Diabetes Research Institute
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Santa Barbara, California • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 1, 2020 · Synced Oct 19, 2026, 2:49 PM EDT
Completed No phase listed Observational

Confirm Rx Insertable Cardiac Monitor SMART Registry

NCT03505801
View directory record Official record
Conditions
Cardiac Arrhythmias, Symptoms and Signs, Atrial Fibrillation
Interventions
Confirm Rx ICM insertion procedure
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,826 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
15
States / cities
Jonesboro, Arkansas • Brandon, Florida • St. Petersburg, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 19, 2026, 2:49 PM EDT
Not yet recruiting Not applicable Interventional

Mobile Health Management of Hypertension

NCT05856955
View directory record Official record
Conditions
Hypertension
Interventions
mHealth Coaching Intervention, Enhanced Usual Care
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 19, 2026, 2:49 PM EDT
Terminated Not applicable Interventional

Physical Therapy vs Remote Exercise for Knee Pain Due to Osteoarthritis (OA)

NCT06167304
View directory record Official record
Conditions
Knee Osteoarthritis, Chronic Pain
Interventions
Technology-implemented exercise therapy, Traditional Physical Therapy
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dissemination of a Brief Dental Fear Intervention

NCT05082298
View directory record Official record
Conditions
Dental Fear
Interventions
Dental FearLess app, In-Chair Treatment Protocol
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years to 100 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional Results available

Improving Glycemic Control in DM2 Patients in the Ambulatory Setting

NCT04800471
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Smart insulin pens and CGM, Point of Care Glucose Group
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 19, 2026, 2:49 PM EDT
Recruiting Not applicable Interventional

SMART Embedded Intervention for Military Postsurgical Engagement Readiness

NCT05050409
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
Brief mindfulness, Mindfulness-Oriented Recovery Enhancement (MORE), Standard care
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 19, 2026, 2:49 PM EDT
Not listed Not applicable Interventional

A Randomized Control Trial of ZEPHYRx Gamified Incentive Spirometry Compared to Traditional Spirometry

NCT04429009
View directory record Official record
Conditions
Thoracic Surgery, Respiratory Therapy
Interventions
ZEPHYRx Respiratory Therapy (RT) System, Standard Incentive Spirometer
Device
Lead sponsor
My Music Machines Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Efficacy of the SMART Device for Overweight and Obese Adults

NCT02119299
View directory record Official record
Conditions
Overweight and Obesity
Interventions
SMART device
Device
Lead sponsor
Scientific Intake Limited Co.
Industry
Eligibility
18 Years to 49 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
4
States / cities
San Diego, California • Waterbury, Connecticut • Coral Gables, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional

Personal Activity Intelligence (PAI) Pilot

NCT03740074
View directory record Official record
Conditions
Overweight and Obesity, Diabetes, Hypertension, Dyslipidemias, Cardiovascular Diseases
Interventions
PAI
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional Results available

Blossom Smart Expander Technology in Breast Reconstruction in Participants With Breast Cancer Undergoing Mastectomy

NCT03657069
View directory record Official record
Conditions
Breast Carcinoma, Breast Disorder
Interventions
Blossom, Breast-Q -Reconstruction module (preoperative) version 2.0 satisfaction with breasts questionnaire
Device · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Oct 19, 2026, 2:49 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Heart-Focused Breathing in Alzheimer's Disease Caregivers

NCT04077450
View directory record Official record
Conditions
Burnout, Caregiver, Quality of Life
Interventions
Online Heart-Focused Breathing Intervention
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Oct 19, 2026, 2:49 PM EDT
Recruiting Not applicable Interventional

Assessing Connected-Health, Pressure-Monitoring Technology for Improving Compression Therapy in Venous Leg Ulcer Treatment

NCT07152717
View directory record Official record
Conditions
Venous Leg Ulcers (VLUs)
Interventions
A connected-health, pressure-sensing system for monitoring sub-bandage pressure during compression therapy
Device
Lead sponsor
Feeltect Limited
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 19, 2026, 2:49 PM EDT
Completed No phase listed Observational Results available

Strategic MAnagement to Optimize Response To Cardiac Resynchronization Therapy Registry

NCT03075215
View directory record Official record
Conditions
Heart Failure
Interventions
Device Programming of the Boston Scientific Cardiac Resynchronization Therapy Defibrillator (CRT-D)
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
2,044 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
29
States / cities
Anchorage, Alaska • Mesa, Arizona • Jonesboro, Arkansas + 26 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional

Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain

NCT04494698
View directory record Official record
Conditions
Acute Low-back Pain, Chronic Low-back Pain, Pain, Intractable
Interventions
Duotherm VibraCool Back Device, TENS 8-channel unit
Device
Lead sponsor
MMJ Labs LLC
Industry
Eligibility
18 Years to 90 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Landover, Maryland • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional

Resistance Exercise and Peer Support with Bands/balls and Digital Support Among Women with Polycystic Ovary Syndrome

NCT06629883
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS)
Interventions
REPS w/BANDS
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional

Values and Options in Cancer Care 2 (VOICE 2) A Randomized Pilot Study

NCT05352451
View directory record Official record
Conditions
Communication, Multidisciplinary
Interventions
Interventional Survey
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
21 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Oct 19, 2026, 2:49 PM EDT
Recruiting No phase listed Observational

Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention

NCT06750731
View directory record Official record
Conditions
Inflammatory Bowel Disease (IBD), Crohn's Disease, Ulcerative Colitis
Interventions
Tappt
Device
Lead sponsor
Mercy Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
New Orleans, Louisiana • Chevy Chase, Maryland • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 19, 2026, 2:49 PM EDT
Completed Not applicable Interventional

The Effects of Heart Rate Variability Biofeedback Training on Hematopoietic Cell Transplantation Patients

NCT04275830
View directory record Official record
Conditions
Hematopoietic Stem Cell Transplantation, Bone Marrow Transplant, Heart Rate Variability, Autonomic Nervous System, Stress, Mood, Psychological Distress, Emotion Regulation, Communication Research, Narrative
Interventions
Baseline Surveys, Heart rate variability biofeedback, Heart rate variability waitlist and Digital storytelling Control intervention
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 23, 2022 · Synced Oct 19, 2026, 2:49 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Infection Watch Study

NCT04623047
View directory record Official record
Conditions
COVID-19 Respiratory Infection, Respiratory Syncytial Virus Infections, Rhinoviral Infections, Influenza Viral Infections
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
10,034 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 19, 2026, 2:49 PM EDT
Terminated Not applicable Interventional Results available

Safety and Effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS)-Assisted Weight Loss

NCT03299881
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Transcutaneous Nerve Stimulator (TENS), Diet & Exercise
Device · Behavioral
Lead sponsor
Elira Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 10, 2021 · Synced Oct 19, 2026, 2:49 PM EDT