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Showing 1–24 of 1,377 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

NCT03015194
View directory record Official record
Conditions
Mitral Valve Failure
Interventions
Edwards SAPIEN 3 transcatheter heart valve, ASHI INTECC Astato XS 20
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional

Impact of Exercise in Parkinson's Disease

NCT03495193
View directory record Official record
Conditions
Parkinson Disease
Interventions
Exercise training, Sleep hygiene
Other · Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
45 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 7, 2026, 5:26 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Optimizing a Technology-based Body and Mind Intervention

NCT05778604
View directory record Official record
Conditions
Fall, Fear of Falling, Physical Inactivity, Sedentary Behavior
Interventions
Physio-feedback, Cognitive reframing, Peer-led exercises, CDC older adults fall prevention
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
60 Years and older
Enrollment
340 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Schedule Intervention to Increase Sustainable Walking Activity in Midlife Working Adults

NCT03272438
View directory record Official record
Conditions
Physical Activity
Interventions
Accelerometer, Step goal, Consistent contexts, Inconsistent contexts
Device · Behavioral
Lead sponsor
Brandeis University
Other
Eligibility
40 Years to 65 Years
Enrollment
149 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 16, 2025 · Synced Sep 7, 2026, 5:26 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Step-up to Quit: Using Low-to-moderate Intensity Exercise for Reducing Smoking Cue Reactivity Among Low-income Smokers

NCT02220465
View directory record Official record
Conditions
Sedentary Lifestyle, Cigarette Smoking
Interventions
PA+ Smoking Cessation (LMPA), Standard Care Smoking Counseling (SCC)
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 59 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Sep 7, 2026, 5:26 AM EDT
Recruiting Not applicable Interventional

Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease

NCT06088355
View directory record Official record
Conditions
Parkinson Disease, Movement Disorders, Neurodegeneration
Interventions
HV-PDAE: High Volume Partnered Dance Aerobic Exercise, MV-PDAE: Moderate Volume Partnered Dance Aerobic Exercise, MV-WALK: Moderate Volume Walking, HV-WALK: High Volume Walking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 7, 2026, 5:26 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Physical Activity Modifies Exercise Responsiveness

NCT07792967
View directory record Official record
Conditions
Multimorbidity
Interventions
SLIMM - Sit less, interact, move more, PB125
Behavioral · Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Engaging Native Hawaiian/Pacific Islanders and Activating Communities to Take Steps (ENACTS)

NCT03484364
View directory record Official record
Conditions
Hypertension
Interventions
ENACTS
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Novel Interruption Management Intervention for New Graduate Nurses During Medication Administration

NCT07599215
View directory record Official record
Conditions
Nurses, Education Nursing, Career Mobility, Simulation Based Learning
Interventions
Experimental: Stay S.A.F.E. Interruption Management Education, Medication Safety Education
Other
Lead sponsor
Baystate Medical Center
Other
Eligibility
Not listed
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional

A New Model to Reach Vulnerable Older Adults With Pain Self-management Support

NCT04095650
View directory record Official record
Conditions
Chronic Pain
Interventions
STEPS (Seniors using Technology to Engage in Pain Self-management)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Sep 7, 2026, 5:26 AM EDT
Not listed Not applicable Interventional

Primary Prevention of Cardiovascular Disease Among Female Hospital Employees: The Heart Smart for Women Intervention

NCT04166097
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
Heart Smart Interventional Program
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 7, 2026, 5:26 AM EDT
Recruiting Not applicable Interventional

J-Tip Use for Paracentesis in Adults With Ascites

NCT06996379
View directory record Official record
Conditions
Evaluate Patient Comfort Level During Paracentesis by Numbing Skin With a Needle-less Device, Instead of Using a Needle to Numb the Skin
Interventions
Experimental J-Tip Needle-Free Injection System, Control (Standard treatment)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mentored Research on Improving Alcohol Brief Interventions in Medical Settings

NCT02978027
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Brief Advice, NIAAA Clinician's Guide, Motivational Interviewing (MI)
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Colorectal Cancer Awareness, Research, Education and Screening (CARES)

NCT01804179
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Immunochemical Fecal Occult Blood Test (I-FOBT) Kit, Standard Intervention (SI) Educational Materials, CARES Intervention Educational Materials, Baseline Visit Survey, Follow-up Questionnaire
Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
50 Years to 75 Years
Enrollment
514 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2022
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2022 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile Technology and Data Analytics to Identify Real-time Predictors of Caregiver Well-Being

NCT04556591
View directory record Official record
Conditions
Caregivers
Interventions
Just-in-time adaptive intervention (JITAI), Control
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Sep 7, 2026, 5:26 AM EDT
Active, not recruiting Not applicable Interventional

Improving Preschool Outcomes by Addressing Maternal Depression in Head Start

NCT04092010
View directory record Official record
Conditions
Maternal Depression
Interventions
Problem-solving education (PSE), Engagement sessions, Usual care
Behavioral
Lead sponsor
Brown University
Other
Eligibility
Female only
Enrollment
388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 7, 2026, 5:26 AM EDT
Completed No phase listed Observational

Cardiopulmonary Exercise Testing in Cirrhotic Patients: a Pilot Study

NCT01658982
View directory record Official record
Conditions
End Stage Liver Disease
Interventions
cardiopulmonary exercise testing
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 1, 2013 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional

Text-Messaging to Motivate Walking in Older African Americans

NCT01697475
View directory record Official record
Conditions
Physical Activity, Motor Activity
Interventions
Motivational text messaging
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
60 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2012 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Comparison of Depression Interventions After Acute Coronary Syndrome

NCT01032018
View directory record Official record
Conditions
Acute Coronary Syndrome, Depression
Interventions
Problem Solving Therapy, Sertraline, citalopram, or bupropion, Standard care
Behavioral · Drug · Other
Lead sponsor
Columbia University
Other
Eligibility
35 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
5
States / cities
New Haven, Connecticut • Atlanta, Georgia • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2017 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Total Health Study

NCT01415206
View directory record Official record
Conditions
Risk Reduction Behavior
Interventions
Extended Staging Health Risk Intervention (S-HRI), Usual Care
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional

Life Skills Improved in Children With Down Syndrome After Using Assistive Technology

NCT05343468
View directory record Official record
Conditions
Down Syndrome, Adaptive Behavior, Quality of Life
Interventions
The MapHabit System
Device
Lead sponsor
MapHabit, Inc.
Industry
Eligibility
7 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Sep 7, 2026, 5:26 AM EDT
Recruiting Not applicable Interventional

Steps Towards Osteoarthritis Prevention

NCT06193343
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries
Interventions
Adaptive Daily Step Promotion
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
16 Years to 40 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 7, 2026, 5:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project H-COVID: Evaluating Hyper-Brief, Online Materials During the COVID-19 Pandemic

NCT04459455
View directory record Official record
Conditions
Anxiety
Interventions
Contain COVID Anxiety SSI, Remain COVID Free SSI
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 7, 2026, 5:26 AM EDT
Recruiting Not applicable Interventional

Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)

NCT05743517
View directory record Official record
Conditions
Ovary Cancer, Endometrial Cancer, Uterine Cancer, Cervical Cancer, Cervix Cancer, Vulvar Cancer, Vaginal Cancer
Interventions
Fit4Treatment
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
60 Years and older · Female only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 7, 2026, 5:26 AM EDT