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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:03 AM EDT

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Showing 1–24 of 163 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: STI/HIV-Plus Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Men's Prevention Apps to Research Efficacy

NCT03965221
View directory record Official record
Conditions
HIV/AIDS, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
Interventions
LYNX, MyChoices
Behavioral
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
15 Years to 29 Years · Male only
Enrollment
381 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
8
States / cities
Tampa, Florida • Atlanta, Georgia • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional

A Web-based Intervention Study to Reduce High-risk Sexual Behavior by Persons Living With HIV AIDS (PLWH)

NCT01198418
View directory record Official record
Conditions
Sexually Transmitted Infections, HIV Infections
Interventions
Experimental
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Male only
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
3
States / cities
Los Angeles, California • San Diego, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated May 12, 2020 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

An Open Label Demonstration Project and Phase II Safety Study of Pre-Exposure Prophylaxis

NCT01772823
View directory record Official record
Conditions
HIV Infection
Interventions
3MV, PCC, Emtricitabine/tenofovir (FTC/TDF (Truvada®))
Behavioral · Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 22 Years · Male only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
12
States / cities
Los Angeles, California • Aurora, Colorado • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional

Repeat Sexually Transmitted Infection (STI) Patients: Tailored Socio-Contextual Intervention to Reduce HIV Risk

NCT01510262
View directory record Official record
Conditions
Sexually Transmitted Infection, HIV
Interventions
Tailored Socio-Contextual Intervention, Standard of Care
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 27, 2017 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

TechStep: Technology-based Stepped Care to Stem Transgender Adolescent Risk Transmission

NCT04000724
View directory record Official record
Conditions
HIV
Interventions
Text Messaging (Text+Step), WebApp (App+Step), Information/No Step
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
15 Years to 24 Years
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
5
States / cities
Los Angeles, California • Boston, Massachusetts • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 21, 2026, 10:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Serologic Assays for the Diagnosis of Herpes Simplex Virus Type 2

NCT01112956
View directory record Official record
Conditions
Genital Herpes
Interventions
Not listed
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
16 Years to 55 Years
Enrollment
2,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
3
States / cities
Baltimore, Maryland • Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2011 · Synced Oct 21, 2026, 10:03 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

NC Young Women's CoOp

NCT02965014
View directory record Official record
Conditions
Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infection (STI), Alcohol and Drug Use
Interventions
Face-to-Face Young Women's CoOp (YWC), mHealth Young Women's CoOp (YWC), HIV Counseling and Testing
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
652 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
4
States / cities
Durham, North Carolina • Greensboro, North Carolina • High Point, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Phase 2 Interventional

Development of an Empowerment Intervention for Young Women Living With HIV

NCT01454921
View directory record Official record
Conditions
HIV
Interventions
Evolution: Young Women Taking Charge and Growing Stronger
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 24 Years · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
Tampa, Florida • Chicago, Illinois • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

HIV Rapid Testing & Counseling in Sexually Transmitted Disease (STD) Clinics in the U.S.

NCT01154296
View directory record Official record
Conditions
HIV/AIDS, Sexually Transmitted Infections
Interventions
RESPECT-2 Counseling
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
5,012 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
9
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2014 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention

NCT03855410
View directory record Official record
Conditions
Tobacco Use, Drug Use, Adolescent Behavior, Alcohol Use, Sexual Risk Behavior
Interventions
S4E, Attention-Matched Control Group
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Ann Arbor, Michigan • Ypsilanti, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Formative Research for an HIV Videogame for Young Black Women

NCT02685410
View directory record Official record
Conditions
HIV Prevention, STI Prevention
Interventions
One Night Stan Prototype
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Oct 21, 2026, 10:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations

NCT06477588
View directory record Official record
Conditions
HIV, Contingency Management, Justice Involved Populations, Status Neutral Interventions, Mental Health, Substance Use
Interventions
Health Navigation, Health Navigation, Employment Navigation plus Contingency Management Intervention
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 21, 2026, 10:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Scaling Effective Behavioral Interventions With MPC Avatar-Based Virtual Training

NCT07880912
View directory record Official record
Conditions
Education, Sex
Interventions
MPC VISTA, Live Virtual Training
Other
Lead sponsor
dfusion Inc
Industry
Eligibility
18 Years and older
Enrollment
365 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Scotts Valley, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 21, 2026, 10:03 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

A Community-University Approach to Preventing HIV

NCT03938077
View directory record Official record
Conditions
HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage, Alcohol Use, Mental Health, Tobacco Use, HIV Testing
Interventions
Storytelling 4 Empowerment
Device
Lead sponsor
University of Michigan
Other
Eligibility
16 Years to 21 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
2
States / cities
Ann Arbor, Michigan • Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 10, 2019 · Synced Oct 21, 2026, 10:03 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

#TranscendentHealth: A Text Messaging Pregnancy Prevention Program for Transgender Boys

NCT07681908
View directory record Official record
Conditions
Pregnancy (Unwanted), Sexually Transmitted Disease (STD), HIV Infection, Sexual Behavior
Interventions
#TranscendentHealth, Universal Sexual Health Program
Behavioral
Lead sponsor
Center for Innovative Public Health Research
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
467 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Clemente, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional

Distress Tolerance and HIV Prevention With XR-NTX Initiation in Opioid Dependence

NCT02602795
View directory record Official record
Conditions
Opiate Dependence, Sexually Transmitted Diseases, HIV
Interventions
Acceptance and Commitment Therapy, Information Motivation Behavioral Model
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 29, 2018 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional

Computer-based Cognitive Behavioral Therapy for Risky Behaviors in Opioid Dependent Patients

NCT01645033
View directory record Official record
Conditions
Opioid Dependence, Hepatitis, HIV
Interventions
computerized Cognitive Behavioral Therapy (CBT), Treatment as Usual (TAU)
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 12, 2014 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Positive Prevention PLUS Program

NCT02540278
View directory record Official record
Conditions
Pregnancy in Adolescence
Interventions
Positive Prevention PLUS
Behavioral
Lead sponsor
California State University, San Bernardino
Other
Eligibility
12 Years to 19 Years
Enrollment
4,267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Bernardino, California
Source: ClinicalTrials.gov public record
Updated Sep 3, 2015 · Synced Oct 21, 2026, 10:03 AM EDT
Not listed Not applicable Interventional

Evaluation of Curriculum for Teen Pregnancy Prevention: Decisions, Responsibility, Empowerment, Accountability, Motivations & Success

NCT03311061
View directory record Official record
Conditions
Teen Pregnancy
Interventions
DREAMS Curriculum
Other
Lead sponsor
Winter Rose Services, LLC
Other
Eligibility
13 Years to 19 Years
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2017 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HIV Prevention Among Vulnerable Male Youth

NCT01771237
View directory record Official record
Conditions
Homosexuality, Male, HIV, Substance-related Disorders, Sexual Dysfunctions, Psychological
Interventions
MyPeeps Manualized Group Intervention, Standard Sexual Health Education
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
16 Years to 20 Years · Male only
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The ProGirls Study

NCT02112201
View directory record Official record
Conditions
Delinquency, HIV Risk, Substance Use, Trauma Exposure
Interventions
Integrated intervention for parents and adolescent girls
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 18 Years · Female only
Enrollment
416 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Accessible Digital Intervention to Promote HIV Testing/Counseling and Prevention Among Adolescents

NCT03713034
View directory record Official record
Conditions
HIV Prevention
Interventions
PlayTest!, Control games
Other
Lead sponsor
Yale University
Other
Eligibility
14 Years to 18 Years
Enrollment
296 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 21, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Trans Women Connected Mobile App for Changes in Sexual Health-related Behavior Among Transgender Women

NCT03897049
View directory record Official record
Conditions
HIV/AIDS, Health Knowledge, Attitudes, Practice, STI
Interventions
Trans Women Connected, General Health App
Behavioral
Lead sponsor
ETR Associates
Other
Eligibility
18 Years to 49 Years
Enrollment
574 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Scotts Valley, California
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Oct 21, 2026, 10:03 AM EDT
Not listed Not applicable Interventional

The Cheeky Study: A Novel Delivery System for CAB-RPV LA

NCT05979714
View directory record Official record
Conditions
HIV Infections
Interventions
Patient-centered injection site, Patient-centered adherence support, Provider education, Improved clinic communication strategies
Other · Behavioral
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Oct 21, 2026, 10:03 AM EDT