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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Safety Planning Intervention (SPI) Clear all
Completed Not applicable Interventional

A Brief Intervention to Reduce Suicide Risk in Military Service Members and Veterans - Study 2 (SAFEMIL)

NCT01360736
View directory record Official record
Conditions
Suicide, Suicide, Attempted
Interventions
Safety Planning - Military (SAFE MIL)
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 89 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional

Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial

NCT05180331
View directory record Official record
Conditions
Suicide, Suicide and Self-harm, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 26 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 17, 2026, 3:01 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Crisis Interventions for Pediatric Providers - Autism Version

NCT07508436
View directory record Official record
Conditions
Autism, Suicide Prevention
Interventions
Safety Planning Intervention, Crisis Interventions for Pediatric Providers - Autism version (CIPP-A)
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Exposure-Based Implementation Strategy to Decrease Clinician Anxiety Around Suicide Prevention

NCT05172609
View directory record Official record
Conditions
Implementation Science
Interventions
Exposure Based Implementation Strategy (EBIS), Implementation as Usual (IAU)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Sep 17, 2026, 3:01 AM EDT
Enrolling by invitation Not applicable Interventional

Pilot Study of a Modified Safety Planning Intervention for Elementary School-Aged Children - Main Study

NCT07564583
View directory record Official record
Conditions
Suicidal Ideation, Suicidal Behaviors
Interventions
Child - Safety Planning Intervention, C-SPI+ecological momentary assessment
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
6 Years to 12 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional

Safety Planning Intervention to Reduce Short Term Risk

NCT03227991
View directory record Official record
Conditions
Suicide, Attempted
Interventions
Safety Planning Intervention, Risk factors and Warning signs
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years and older
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Worcester, Massachusetts • New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Sep 17, 2026, 3:01 AM EDT
Recruiting Not applicable Interventional

Design and Feasibility of an SMS-based Safety Planning Intervention

NCT07365579
View directory record Official record
Conditions
Suicidal Ideation and Behavior
Interventions
Text Messaging based Safety Planning Intervention, Facilitated Referral to Crisis Resources
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 24 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional Results available

Suicide Prevention Intervention for At-Risk Individuals in Transition

NCT02759172
View directory record Official record
Conditions
Suicide
Interventions
Safety Planning Intervention
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Flint, Michigan • Cranston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 17, 2026, 3:01 AM EDT
Not yet recruiting Not applicable Interventional

Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial

NCT07628192
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Safety Plan, Depression / Major Depressive Disorder, Hopelessness
Interventions
CAMS Brief Intervention, Stanley-Brown Safety Planning Intervention
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
12 Years to 17 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Enrolling by invitation Not applicable Interventional

A Comparison of Two Brief Suicide Prevention Interventions Tailored for Youth on the Autism Spectrum

NCT05398250
View directory record Official record
Conditions
Suicidal Ideation, Suicidal and Self-injurious Behavior, Suicide, Autism Spectrum Disorder
Interventions
Safety Planning Intervention tailored for Autistic Individuals, Safety Planning Intervention Tailored for Autistic Individuals Plus Structured Follow-Up Contacts
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 99 Years
Enrollment
1,665 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
5
States / cities
Baltimore, Maryland • Chapel Hill, North Carolina • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional Results available

SAFER: A Brief Intervention Involving Family Members in Suicide Safety Planning

NCT03034863
View directory record Official record
Conditions
Suicide
Interventions
Safe Actions for Families to Encourage Recovery, Individual Safety Planning Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 9, 2021 · Synced Sep 17, 2026, 3:01 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Suicide Prevention for Sexual and Gender Minority Youth (Randomized Controlled Trial)

NCT05669976
View directory record Official record
Conditions
Suicide
Interventions
Safety Planning Intervention with Navigation Services, Safety Planning Intervention
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
15 Years to 29 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional

Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Randomized Trial

NCT05202756
View directory record Official record
Conditions
Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS), EMA Monitoring Only
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Enrolling by invitation Not applicable Interventional

Safety Planning Intervention Telehealth Service Model in Emergency Departments

NCT05307432
View directory record Official record
Conditions
Suicide, Suicidal Ideation
Interventions
SPI+ Delivered by ED Staff, SPI+ Delivered by SPCC Clinicians
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
2,814 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Advancing Suicide Intervention Strategies for Teens During High Risk Periods

NCT05078970
View directory record Official record
Conditions
Suicide Attempts, Suicidal Ideation, Suicide and Self-harm, Suicide Threat
Interventions
Safety Planning Intervention+ (SPI+), Collaborative Assessment and Management of Suicidality (CAMS), Treatment As Usual
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 17 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
2
States / cities
Columbus, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Suicide Prevention for Sexual and Gender Minority Youth (Open Trial)

NCT05087966
View directory record Official record
Conditions
Suicide
Interventions
Safety Planning Intervention with Navigation Services
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
15 Years to 29 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 17, 2026, 3:01 AM EDT
Recruiting Not applicable Interventional

Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

NCT06151158
View directory record Official record
Conditions
Suicide, Attempted, Suicide Ideation, Suicide, Suicide Prevention
Interventions
Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
12 Years to 24 Years
Enrollment
484 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
6
States / cities
St. Petersburg, Florida • Baltimore, Maryland • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional Results available

Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Open Trial

NCT05180383
View directory record Official record
Conditions
Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Phase 1 Interventional

Mindfulness-Based Cognitive Therapy + Safety Planning For Suicidal Behavior

NCT01826240
View directory record Official record
Conditions
Monopolar Depression, Single Episode or Unspecified, Suicidal and Self-injurious Behaviour
Interventions
MBCT+SPI
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Suicide Prevention for Sexual and Gender Minority Youth (Case Series)

NCT04757649
View directory record Official record
Conditions
Suicide
Interventions
Safety Planning Intervention with Navigation Services
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
15 Years to 29 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2024 · Synced Sep 17, 2026, 3:01 AM EDT
Recruiting Not applicable Interventional

Testing an Intergenerational Model of Suicide Risk in Mother-child Dyads

NCT06463054
View directory record Official record
Conditions
Emotion Regulation
Interventions
Dialectical Behavior Therapy Skills Group Training, Safety Planning Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 17, 2026, 3:01 AM EDT
Completed Not applicable Interventional Results available

Improving Treatment Outcomes for Suicidal Veterans With PTSD

NCT04690582
View directory record Official record
Conditions
Suicidal Ideation, Suicide, Attempted, Ptsd
Interventions
Cognitive Processing Therapy (CPT), Crisis Response Plan (CRP), Safety Planning Intervention (SPI), Narrative Assessment
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Sep 17, 2026, 3:01 AM EDT
Not yet recruiting Not applicable Interventional

Electronic, Self-Guided Safety Plan in Adolescents: Project SAFER

NCT06868407
View directory record Official record
Conditions
Suicide Attempt, Suicide Ideation
Interventions
Psychoeducation about Suicide Crisis Resources (Control Intervention), Experimental: Self-Guided Electronic Safety Plan Intervention
Behavioral
Lead sponsor
University of Denver
Other
Eligibility
13 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Sep 17, 2026, 3:01 AM EDT
Recruiting Not applicable Interventional

Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial (2)

NCT05180344
View directory record Official record
Conditions
Suicide, Suicide and Self-harm, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 26 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Sep 17, 2026, 3:01 AM EDT