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Showing 1–24 of 54 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Safflower OIl Clear all
Completed Not applicable Interventional

Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health

NCT05295719
View directory record Official record
Conditions
Obesity, Inflammation, Human Microbiome, Insulin Resistance, Dyslipidemias
Interventions
Omega-3 polyunsaturated fatty acid, High-Intensity Interval Training, Safflower oil, Low-intensity training
Dietary Supplement · Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 65 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus

NCT02170870
View directory record Official record
Conditions
Dyspepsia, Diabetes Mellitus With Gastrointestinal Symptoms
Interventions
Exendin 9-39, Microlipid, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Conjugated Linoleic Acid on Body Fat in Overweight Children

NCT00575991
View directory record Official record
Conditions
Overweight
Interventions
Conjugated linoleic acid
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
6 Years to 10 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 12, 2012 · Synced Sep 3, 2026, 6:42 AM EDT
Terminated Not applicable Interventional

Fat Tolerance From Lipid Emulsion Infusion Packaged in Glass or Plastic

NCT00278928
View directory record Official record
Conditions
Hypertriglyceridemia
Interventions
Liposyn III 20% (lipid infusion), Intralipid 20% (lipid infusion)
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
2 Days to 10 Days
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Sep 3, 2026, 6:42 AM EDT
Not listed Phase 2Phase 3 Interventional

The Influence of PRN Omega-3 Nutritional Supplement on Visual Acuity

NCT02260973
View directory record Official record
Conditions
Cataract, Dry Eye Disease
Interventions
Omega-3 (Triglyceride form)
Dietary Supplement
Lead sponsor
Physician Recommended Nutriceuticals
Industry
Eligibility
30 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Lexington, Kentucky • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 3, 2016 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Not applicable Interventional

Supplementation With Conjugated Linoleic Acid (CLA) as Complementary Therapy in the Management of Type 2 Diabetes Mellitus (Women's Diabetes Study)

NCT01121471
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Conjugated Linoleic Acid (CLA), Safflower OIl
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 11, 2010 · Synced Sep 3, 2026, 6:42 AM EDT
Not listed Not applicable Interventional

Micronutrients as Adjunctive Treatment for Bipolar Disorder

NCT03541031
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Micronutrient & Fish oil, Olive oil & Safflower oil
Dietary Supplement
Lead sponsor
Eastern Maine Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bangor, Maine
Source: ClinicalTrials.gov public record
Updated Jul 12, 2018 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Phase 2 Interventional Results available

Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposure

NCT02911688
View directory record Official record
Conditions
Allergic Asthma
Interventions
gamma tocopherol, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)

NCT02697201
View directory record Official record
Conditions
Insulin Resistance
Interventions
Intralipid, Saline
Drug
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Not applicable Interventional

Healthy Oils for Women (HOW Study)

NCT02063165
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
High Linoleic Safflower Oil
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
50 Years to 69 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure

NCT01534663
View directory record Official record
Conditions
Heart Failure
Interventions
Glutamine and Fish Oil Supplementation, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
35 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Early Phase 1 Interventional

Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy

NCT01306838
View directory record Official record
Conditions
Short Bowel Syndrome, Necrotizing Enterocolitis, Small Intestine Perforation
Interventions
MicroLipid and fish oil, Routine care
Dietary Supplement · Other
Lead sponsor
Wake Forest University
Other
Eligibility
1 Day to 60 Days
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 3, 2026, 6:42 AM EDT
Terminated Phase 3 Interventional Results available

Crossover Study to Assess the Efficacy and Safety of UX007 in the Treatment of Movement Disorders Associated With Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)

NCT02960217
View directory record Official record
Conditions
Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)
Interventions
UX007, Placebo
Drug
Lead sponsor
Ultragenyx Pharmaceutical Inc
Industry
Eligibility
6 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
4
States / cities
Aurora, Colorado • Miami, Florida • Norcross, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Sep 3, 2026, 6:42 AM EDT
Not listed Not applicable Interventional

Effects of Lutein Supplementation on Cognition and MPOD in Multiple Sclerosis Patients-

NCT04843813
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Lutein, Placebo
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 64 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Not applicable Interventional

A Comparison of Two Types of Injected Nutritional Supplements in Patients With AIDS and Pneumocystis Carinii Pneumonia (PCP)

NCT00002275
View directory record Official record
Conditions
HIV Infections
Interventions
Fat Emulsion 2%, Fat Emulsion 20%
Drug
Lead sponsor
Abbott
Industry
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 19, 2009 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Effects of Peanuts and Peanut Products on Glucose Control and Vascular Function

NCT01405300
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Control, Peanut
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 50 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Phase 3 Interventional Results available

Metformin Therapy for Overweight Adolescents With Type 1 Diabetes

NCT01881828
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Metformin (glucophage), oral placebo
Drug · Other
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
12 Years to 19 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2020 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Phase 2Phase 3 Interventional

The Influence of PRN Dry Eye Omega-3 Nutritional Regimen on Tear Osmolarity In Cases Of Dry Eye Disease

NCT02260960
View directory record Official record
Conditions
Dry Eye Disease
Interventions
Omega-3 (Triglyceride form)
Dietary Supplement
Lead sponsor
Physician Recommended Nutriceuticals
Industry
Eligibility
18 Years to 90 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 3, 2016 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Phase 2 Interventional Results available

Effects of CLA Supplements on Body Weight and Fat Oxidation

NCT00204932
View directory record Official record
Conditions
Obesity
Interventions
conjugated linoleic acid
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 44 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced Sep 3, 2026, 6:42 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Fish Oil on Athlete's Executive Function

NCT04570995
View directory record Official record
Conditions
Brain Health, Brain Function, Brain Development
Interventions
Fish Oil, Safflower Oil
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Male only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Class of Dietary Fat Affect Insulin Resistance?

NCT01541592
View directory record Official record
Conditions
Insulin Resistance
Interventions
Dietary fat
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 25, 2014 · Synced Sep 3, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Effect of Lipid Infusion on Toll Like Receptor 4 (TLR4) Signaling

NCT01740817
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Intralipid 20%, Saline
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2016 · Synced Sep 3, 2026, 6:42 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Healthy Cookie Study: Understanding How Healthy Cookies Affect Fat in the Blood,

NCT02841618
View directory record Official record
Conditions
Healthy Adults
Interventions
High Linoleic Acid Healthy Cookies, High Oleic Acid Healthy Cookies
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 80 Years
Enrollment
123 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 3, 2026, 6:42 AM EDT
Active, not recruiting Not applicable Interventional

Ritual Synbiotic+, a Dietary Supplement Designed to Impact Gastrointestinal Health, Mood, and Behavior in Women

NCT06834984
View directory record Official record
Conditions
Gastrointestinal Disease Symptoms
Interventions
Prebiotic, probiotic, postbiotic combination, Placebo
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
25 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 3, 2026, 6:42 AM EDT