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Showing 1–24 of 107 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Saturated Fat Diet Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.

NCT06449287
View directory record Official record
Conditions
Ketogenic Diet, Weight Loss
Interventions
Diet, Blood Draw, Ketone/Glucose Monitoring, Body Composition, Urine Analysis, Neuropsychological Measures - ANAM
Other · Biological · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Phase 2 Interventional

Reduction of Triglycerides in Women on Hormone Replacement Therapy

NCT00023543
View directory record Official record
Conditions
Cardiovascular Diseases, Atherosclerosis, Postmenopause, Heart Diseases
Interventions
Diet, fat-restricted, Exercise
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
52 Years to 60 Years · Female only
Enrollment
508 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Sep 2, 2026, 5:59 PM EDT
Recruiting Not applicable Interventional

Well-Formulated Ketogenic Diet Polycystic Kidney Disease

NCT06325644
View directory record Official record
Conditions
Polycystic Kidney Disease
Interventions
Ketogenic Diet, Ketone/Glucose Monitoring, CGM/CKM, Blood Draw, Body Composition, Change in glomerular filtration rate (mg/mmol) via magnetic resonance imaging (MRI) .
Other · Biological
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Saturated Fat on Large Low-density Lipoprotein (LDL) and High-density Lipoprotein (HDL)

NCT00895141
View directory record Official record
Conditions
Dyslipidemia
Interventions
Saturated Fat Diet
Dietary Supplement
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
18 Years to 70 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2013 · Synced Sep 2, 2026, 5:59 PM EDT
Terminated Not applicable Interventional

Nutritional Treatment of Overweight Adolescents With Cardiovascular Risk Factors (PowerUp)

NCT00477477
View directory record Official record
Conditions
Childhood Obesity, Dyslipidemia, Insulin Resistance, Hypertension
Interventions
Diet
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 17 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 26, 2014 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional

Lean Beef Consumption and Insulin Sensitivity in Men and Women With Risk Factors for Diabetes

NCT03202680
View directory record Official record
Conditions
Metabolic Syndrome, PreDiabetes
Interventions
USDA Style Diet, Lean Beef Diet
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 74 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Avocado Consumption on Vascular Health

NCT01595607
View directory record Official record
Conditions
Focus: Avocado Consumption & Vascular Health
Interventions
Diet Treatment
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
28 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Sep 2, 2026, 5:59 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Healthy Options At Pantries (HOAP) Study

NCT07729436
View directory record Official record
Conditions
Food Choice, Implementation Science, Food Insecurity, Diet, Healthy, Behavioral Economics
Interventions
Behavioral economics-based Healthy Options At Pantries (HOAP) digital nudge intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional

High Fat Diet II on Weight Loss

NCT00525850
View directory record Official record
Conditions
Obesity
Interventions
high fat diet, low saturated fat diet
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 1, 2011 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study)

NCT00928005
View directory record Official record
Conditions
Overweight, Obesity, Type 2 Diabetes, Prediabetes
Interventions
Weight loss diet, Weight loss diet plus exercise
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
30 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

NCT05268042
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease, Obesity
Interventions
Moderately carbohydrate-restricted diet, Fat-restricted diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketogenic Intervention in Depression

NCT06080932
View directory record Official record
Conditions
Depression, Ketosis
Interventions
Ketogenic Diet, NIH Toolbox, gradCPT, Resting-state fMRI, Task-fMRI, CGM/CKM, Blood Draw, Sleep Monitoring, Ketone/Glucose Monitoring, Body Composition, PHQ-9, WHO-5, SKID
Other · Biological · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Dietary Intervention on Insulin Requirements in Type 1 Diabetes

NCT04944316
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Dietary intervention
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Protein and Insulin Sensitivity Study

NCT00508937
View directory record Official record
Conditions
Insulin Resistance, Type 2 Diabetes, Metabolic Syndrome, Cardiovascular Disease, Dyslipidemia
Interventions
Diet
Other
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
18 Years and older
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
2
States / cities
Berkeley, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 22, 2020 · Synced Sep 2, 2026, 5:59 PM EDT
Not listed Not applicable Interventional

Effect of DASH on HF Outcomes Heart Failure Status in Older Adults (DASH HF)

NCT06296862
View directory record Official record
Conditions
Heart Failure
Interventions
Dietary Approaches to Stop Hypertension Diet
Other
Lead sponsor
University of Georgia
Other
Eligibility
65 Years to 110 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diet Modulation of Bacterial Sulfur and Bile Acid Metabolism and Colon Cancer Risk

NCT03550885
View directory record Official record
Conditions
Colorectal Cancer
Interventions
High taurine and saturated fat diet, Low in taurine and saturated fat diet
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
45 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 2, 2026, 5:59 PM EDT
Recruiting Not applicable Interventional

Mediterranean Diet Versus Western Diet on Fatigue in Autoimmune Hepatitis Patients

NCT06250309
View directory record Official record
Conditions
Autoimmune Hepatitis
Interventions
Dietary assignment
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 2, 2026, 5:59 PM EDT
Enrolling by invitation Phase 1Phase 2 Interventional

Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet

NCT06369571
View directory record Official record
Conditions
Epilepsy, Dyslipidemia
Interventions
Atorvastatin 10mg, Modification of dietary fat composition
Drug · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Anti-inflammatory Effects of Fiber

NCT02781350
View directory record Official record
Conditions
Postprandial Inflammation
Interventions
HFHC meal, HFHC MEAL plus Fiber
Other · Dietary Supplement
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 24, 2016 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional

Efficacy and Safety of the DASH Diet in Adults With Moderate Chronic Kidney Disease: Pilot Study

NCT02059811
View directory record Official record
Conditions
Hypertension, Chronic Kidney Disease
Interventions
DASH Diet, Control Diet
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 2, 2014 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Protein Sources and Atherogenic Dyslipidemia

NCT01427855
View directory record Official record
Conditions
Cardiovascular Disease, Dyslipidemia, Insulin Resistance, Inflammation
Interventions
High saturated fat red meat diet, High saturated fat non-meat diet, High saturated fat white meat diet, Low saturated fat red meat diet, Low saturated fat white meat diet, Low saturated fat non meat diet
Other
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
30 Years to 65 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Sep 2, 2026, 5:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Menu to Meal (M2M) Menu Labeling Intervention Study

NCT07329452
View directory record Official record
Conditions
Behavior, Eating
Interventions
Paper menu, Digital menu condition
Behavioral
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bryan, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 2, 2026, 5:59 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Daily Egg Consumption and Cognitive Function in Older Adults

NCT05460624
View directory record Official record
Conditions
Cognition
Interventions
Egg-containing breakfast, Typical American-style breakfast excluding eggs
Other
Lead sponsor
Indiana University
Other
Eligibility
65 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 27, 2023 · Synced Sep 2, 2026, 5:59 PM EDT
Active, not recruiting Not applicable Interventional

Physical Activity and Nutrition to Halt Elevated Risk in the Pancreas Interception Center

NCT06712797
View directory record Official record
Conditions
Pancreatic Ductal Adenocarcinoma, Intraductal Papillary Mucinous Neoplasm
Interventions
Physical Activity (PA), Nutrition (N)
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 2, 2026, 5:59 PM EDT