- Conditions
- Periodontitis, Chronic
- Interventions
- Hydrogen Peroxide Gel, 13 weeks, Hydrogen Peroxide Gel, 26 weeks, Scaling and Root planing group
- Drug · Other
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Loma Linda, California
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Showing 25–48
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- Conditions
- Chronic Periodontitis
- Interventions
- Scaling and root planing, Scaling and root planing with solution
- Procedure
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 30 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Lincoln, Nebraska
- Conditions
- Cardiovascular Disease, Coronary Heart Disease, Myocardial Infarction, Cerebrovascular Accident
- Interventions
- Periodontal Treatment: SRP, Referral
- Procedure
- Lead sponsor
- University at Buffalo
- Other
- Eligibility
- Up to 75 Years
- Enrollment
- 303 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2005
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Periodontitis, Infant, Premature
- Interventions
- Periodontal scaling and root planing, Scaling and root planing
- Procedure
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 16 Years and older · Female only
- Enrollment
- 823 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Periodontitis (Stage 3)
- Interventions
- Emanate Perio PODS
- Device
- Lead sponsor
- McGuire Institute
- Industry
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 8
- States / cities
- Fullerton, California • New London, Connecticut • Boston, Massachusetts + 5 more
- Conditions
- Periodontal Disease
- Interventions
- Periodontal therapy
- Other
- Lead sponsor
- The Forsyth Institute
- Other
- Eligibility
- 25 Years and older
- Enrollment
- 157 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2017
- U.S. locations
- 5
- States / cities
- Edwardsville, Illinois • Cambridge, Massachusetts • Ann Arbor, Michigan + 2 more
- Conditions
- Periodontal Disease
- Interventions
- Periodontal Scaling and Root Planing
- Procedure
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Periodontal Disease, Periodontitis
- Interventions
- Scaling and root planing
- Procedure
- Lead sponsor
- Texas A&M University
- Other
- Eligibility
- Not listed
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Periodontitis
- Interventions
- PerioSept(r)
- Drug
- Lead sponsor
- Geistlich Pharma AG
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Diabetes, Periodontitis
- Interventions
- Hyperbaric Oxygen therapy, Conventional Wound Therapies
- Device · Other
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 35 Years to 80 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- Diabetes Mellitus, Type II, Periodontitis
- Interventions
- Chlorhexidine gluconate oral rinse, Scaling & Root Planing, Soft Picks
- Drug · Procedure · Device
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 25 Years and older
- Enrollment
- 116 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2021
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Periodontal Diseases, Periodontitis, Apical, Chronic Nonsuppurative, Suppuration of Gingival Crevice
- Interventions
- Scaling and Root Planing, Diode Laser + Scaling and Root Planing
- Procedure
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 30 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- Lincoln, Nebraska
- Conditions
- Periodontal Diseases, Premature Birth
- Interventions
- Scaling and root planing
- Procedure
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- Female only
- Enrollment
- 2,100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2009
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Periodontitis Chronic Generalized Severe, Periodontitis Chronic Generalized Moderate
- Interventions
- leukocyte platelet rich fibrin (L-PRF), Scaling and Root Planing
- Biological · Procedure
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Cardiovascular Diseases, Diabetes Type 2
- Interventions
- Subgingival chlorhexidine irrigation, Dental Supplies, Periodonal Treatment
- Drug · Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 786 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina • Kannapolis, North Carolina
- Conditions
- Periodontal Disease, Stroke, TIA
- Interventions
- Intensive dental treatment, Standard dental treatment, Arestin
- Procedure · Drug
- Lead sponsor
- University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina • Columbia, South Carolina
- Conditions
- Periodontal Diseases, Dental Diseases
- Interventions
- Scaling and root planing
- Procedure
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Periodontal Diseases
- Interventions
- BioXclude™
- Procedure
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2027
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Snoring, Mouth Breathing, Daytime Sleepiness, Periodontitis
- Interventions
- Oral appliance therapy plus scaling and root planing on left or right of mouth
- Device
- Lead sponsor
- Texas A&M University
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Periodontitis, Diabetes Mellitus Type 2
- Interventions
- local antibiotic application of topical minocycline, Scaling and Root Planing
- Drug · Procedure
- Lead sponsor
- Case Western Reserve University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Inflammation, Periodontal Disease, Gingivitis
- Interventions
- Plaque disclosing toothpaste, Non-plaque disclosing toothpaste
- Other
- Lead sponsor
- Marshfield Clinic Research Foundation
- Other
- Eligibility
- 21 Years to 84 Years
- Enrollment
- 112 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Marshfield, Wisconsin
- Conditions
- Periodontitis
- Interventions
- scaling and root planing, local tetracycline, systemic metronidazole and amoxicillin, surgery, local antibiotics and systemic metronidazole and amoxicillin, local tetracycline and periodontal surgery, periodontal surgery and systemic metronidazole and amoxicillin, surgery, local tetracycline, systemic metronidazole and amoxicillin
- Other · Drug
- Lead sponsor
- The Forsyth Institute
- Other
- Eligibility
- 20 Years and older
- Enrollment
- 187 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2004
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Periodontitis, Attachment Loss, Periodontal
- Interventions
- Minimally invasive periodontal therapy with use of Emdogain, Minimally invasive periodontal therapy without the use of Emdogain
- Procedure
- Lead sponsor
- Texas A&M University
- Other
- Eligibility
- 30 Years to 75 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Obesity, Periodontitis
- Interventions
- Non-surgical periodontal therapy will be administered
- Procedure
- Lead sponsor
- Louisiana State University Health Sciences Center in New Orleans
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana